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CDS information : Conca_00110


close this sectionLocation

Organism
StrainATCC 27449 (=NBRC 13477)
Entry nameConcanamycin A
Contig
Start / Stop / Direction77,903 / 78,181 / + [in whole cluster]
77,903 / 78,181 / + [in contig]
Location77903..78181 [in whole cluster]
77903..78181 [in contig]
TypeCDS
Length279 bp (92 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.1 modification addition of extender units
Productputative acyl carrier protein
Product (GenBank)methoxymalonate biosynthesis protein
Gene
Gene (GenBank)
EC number
Keyword
  • methoxymalonyl-ACP
Note
Note (GenBank)
  • ORF 2*
Reference
ACC
PmId
[16207901] Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. (Microbiology. , 2005)
Related Reference
ACC
Q8KUG2
NITE
Ansam_00160
PmId
[11960423] Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. (J Am Chem Soc. , 2002)
[11996558] Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B. (J Am Chem Soc. , 2002)
Family/Domain
FD
IPR009081

close this sectionSequence

selected fasta
>putative acyl carrier protein [methoxymalonate biosynthesis protein]
MNVMTMPSEGTVEKELLDFLHVRTKTVWEEDTDLFAAGGLSSLFAMELVVHLEKSYGIAI
RGADLRLDNFRTVTGMAALVRRLRAAAGDGGE
selected fasta
>putative acyl carrier protein [methoxymalonate biosynthesis protein]
ATGAACGTCATGACCATGCCATCCGAAGGGACCGTGGAGAAGGAACTCCTCGACTTCCTG
CACGTACGCACCAAGACCGTCTGGGAAGAGGACACCGACCTCTTCGCGGCCGGCGGACTC
TCGTCCCTGTTCGCCATGGAACTCGTCGTCCACCTGGAGAAGTCCTACGGCATCGCGATC
CGGGGCGCCGATCTGCGGCTGGACAACTTCCGTACCGTCACGGGAATGGCGGCACTGGTC
CGCCGTCTGCGCGCGGCAGCCGGGGACGGCGGTGAGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR009081 Acyl carrier protein-like (Domain)
 [4-84]  5.59999989417023e-12 SSF47336
SSF47336   ACP_like
 [8-81]  PS50075
PS50075   ACP_DOMAIN
 [13-82]  2e-12 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
 [16-80]  6.00000000000001e-07 PF00550
PF00550   PP-binding
SignalP No significant hit
TMHMM No significant hit