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CDS information : Dynm_00210


close this sectionLocation

Organism
StrainATCC 53710 (=NBRC 15963)
Entry nameDynemicin
Contig
Start / Stop / Direction34,326 / 33,652 / - [in whole cluster]
34,326 / 33,652 / - [in contig]
Locationcomplement(33652..34326) [in whole cluster]
complement(33652..34326) [in contig]
TypeCDS
Length675 bp (224 aa)
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close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative HxlR family transcriptional regulator
Product (GenBank)DynU8
GenedynU8
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • putative transcriptional regulator; CalU8-like protein
Reference
ACC
PmId
[18328078] The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. (FEMS Microbiol Lett. , 2008)
Related Reference
ACC
Q8GMD6
NITE
C1027_00570
PmId
[21250756] Improvement of the enediyne antitumor antibiotic C-1027 production by manipulating its biosynthetic pathway regulation in Streptomyces globisporus. (J Nat Prod. , 2011)
Family/Domain
FD
IPR002577

close this sectionSequence

selected fasta
>putative HxlR family transcriptional regulator [DynU8]
MGLLKDRRTYDQQCGLAYALDVLGERWTLLIVRELLIRPRRYGELLDALQGIGTNLLADR
LGFLVEAGLVRPLDPQRRTAGYALTELGERMREPVLSLARFGLTYAAHQPPPAASVTRPA
WAILATDAMLDDTRAPGIDEVYGFDVDGEQFHVVVEGGRAVLHPTAAPDATLHVKTDAKT
FFQLGVRRLDPLEAVLAGSVQVSGPPAAMSRCLRLLGLAGNPLG
selected fasta
>putative HxlR family transcriptional regulator [DynU8]
ATGGGGCTGCTGAAGGACCGACGCACCTACGACCAACAGTGCGGACTGGCCTATGCGCTG
GACGTTCTCGGCGAACGCTGGACTTTGCTGATCGTCCGGGAGCTGCTGATCCGGCCCCGT
CGCTACGGCGAACTCCTCGATGCTTTGCAAGGAATCGGCACCAACCTTCTGGCCGACCGG
CTCGGCTTCCTCGTCGAAGCGGGGCTGGTCCGGCCGCTCGATCCGCAGCGGCGGACCGCG
GGCTACGCGCTGACCGAGTTGGGTGAGCGGATGCGGGAGCCGGTGCTGAGCCTGGCCCGG
TTCGGCCTGACCTACGCCGCCCACCAGCCGCCGCCGGCCGCTTCGGTGACCCGGCCGGCC
TGGGCGATCCTCGCCACCGACGCGATGCTCGACGACACCCGCGCCCCCGGGATCGACGAG
GTCTACGGCTTCGACGTCGACGGCGAGCAGTTCCACGTCGTGGTGGAGGGCGGCCGGGCG
GTCCTGCACCCCACCGCCGCGCCCGACGCGACACTCCACGTGAAGACCGACGCGAAGACC
TTCTTCCAGCTCGGGGTGCGGCGGCTGGACCCGCTGGAGGCGGTGCTCGCCGGCTCGGTG
CAGGTCTCCGGGCCGCCGGCCGCCATGTCGCGCTGCCTGCGGCTGCTCGGCCTGGCCGGC
AACCCGCTCGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR002577 Helix-turn-helix, HxlR type (Domain)
 [22-108]  6e-13 PF01638
PF01638   HxlR
 [14-110]  PS51118
PS51118   HTH_HXLR
IPR003033 SCP2 sterol-binding domain (Domain)
 [108-217]  6.59999852526375e-10 SSF55718
SSF55718   SCP2
 [133-210]  5.5e-07 PF02036
PF02036   SCP2
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [13-97]  2.2e-06 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
SignalP No significant hit
TMHMM No significant hit