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CDS information : FR008_00060


close this sectionLocation

Organism
StrainFR-008
Entry nameFR-008
Contig
Start / Stop / Direction13,315 / 10,298 / - [in whole cluster]
13,315 / 10,298 / - [in contig]
Locationcomplement(10298..13315) [in whole cluster]
complement(10298..13315) [in contig]
TypeCDS
Length3,018 bp (1,005 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
ProductLuxR family transcriptional regulator
Product (GenBank)FscRIV
Gene
Gene (GenBank)fscRIV
EC number
Keyword
Note
Note (GenBank)
  • putative transcriptional regulator
Reference
ACC
PmId
[14652074] Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex. (Chem Biol. , 2003)
[25575546] Production of the antibiotic FR-008/candicidin in Streptomyces sp. FR-008 is co-regulated by two regulators, FscRI and FscRIV, from different transcription factor families. (Microbiology. , 2015)
Related Reference
ACC
Q9L4W1
NITE
Nysta_00170
PmId
[14973031] In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. (J Bacteriol. , 2004)

close this sectionSequence

selected fasta
>LuxR family transcriptional regulator [FscRIV]
MWLRWAGDRSRGAAPGRSGSAGPPSLAPSDARESPVPHRSRAVPPAPPLVGRAHQLDVLA
RHADAARAGRPRLVLLDGPAGIGKTALLRAALAEDGPLAGMTTLYGSCRAVDVATGYSGV
RALFGGLGLTGRKGRTSPLLVGGARRALPALAADPGELDADPGSTFSVLQGLYWLAANLM
ADGPLVLVLDDVHWCDERSLRWLDFLLRRADGLPLLVVAAHRTGTGLTAPDALADLVAHH
LPASLGLGPLDTAEVAELTAHSFPEQDPLPSFVGRLLSVTGGSPLEIVRLLRDLRSAGLG
PDDTGTARLAQAGGKVVAASVRGVLEHQPDWVRQVARAVAVLGDEDRTYLAALGRVSVVH
VEEAVEILRDAGLIHPGHLELSHDLVRAAVLDAVGASGVAVLRRRAARLLSDVGRSPEEI
ATQLLLVPGTPDDWAVSVLRDAAAQAEQRGACEAAARYLERVREAEPKDPDVLSRLGKAL
AETDPARSVTLLHEAHSLTTDVRARAATAVQLGLTCLAVQQSPDGARALTEALDALDAEL
GPEPEPADRELRTLTESALLIVGSDEKATLPDILRRTEGLTPQPGDTPAQRQQLAMLSVL
SAAEGGGAEETVGRARRALRAPGVPLGVWSLLPTSLALSLADENEAAEEVLETVLRGSGD
TAAVWTYVLALSTRSLFRLENGAVPDAMADAQTALEILGQERWGDTATMPHTAYASVLTE
RGDPGRALEALDAIKRPHLDRFVWEYHWYLMARGRALAADGDLDGALQVFGSCGASMAEA
GLTNPVLAPWWLETACLLGEAGRGEEAGRAAAHGTRLAERWGTRRALGYAALARGAAARG
TARTGALREAVALLADSPARSGHARGLLLLGRALVEDGAVREGREHLREAVGLARRCGCV
ALARRARDELIAAGGRMREVTASPLDMLTGTERTVAGLVASGAGNREVAESLFVTVRTVE
LHLTSVYRKLGVARRGDLTEALREAGATARPAAERRPGHAKRRNP
selected fasta
>LuxR family transcriptional regulator [FscRIV]
ATGTGGCTCCGGTGGGCAGGTGACCGGTCCCGGGGCGCCGCCCCGGGCCGTTCCGGTTCC
GCCGGGCCGCCGTCCCTGGCCCCGTCCGACGCGAGGGAGAGCCCTGTGCCTCACCGGTCC
CGTGCCGTGCCCCCGGCCCCGCCCCTCGTCGGCAGGGCCCACCAGCTCGACGTCCTCGCC
CGGCACGCGGACGCCGCCCGCGCGGGAAGACCCCGCCTGGTGCTCCTGGACGGTCCCGCC
GGAATCGGCAAGACCGCACTGCTGCGCGCCGCCCTGGCCGAGGACGGCCCCCTCGCCGGC
ATGACCACCCTGTACGGCTCCTGCCGCGCCGTCGACGTCGCCACGGGCTACAGCGGGGTC
CGCGCCCTGTTCGGCGGACTCGGCCTGACCGGCCGCAAGGGCCGTACCTCGCCGCTCCTT
GTCGGCGGCGCCCGGCGCGCGCTGCCCGCCCTCGCCGCCGACCCGGGGGAGCTGGACGCC
GACCCCGGCAGCACCTTCTCCGTCCTCCAGGGCCTGTACTGGCTCGCGGCCAACCTCATG
GCGGACGGCCCCCTGGTGCTCGTCCTCGACGACGTCCACTGGTGCGACGAGCGGTCCCTG
CGCTGGCTCGACTTCCTGCTGCGCCGCGCGGACGGCCTGCCGCTGCTCGTCGTCGCCGCC
CACCGCACCGGCACCGGCCTCACCGCTCCCGACGCCCTCGCCGACCTGGTCGCCCACCAC
CTGCCGGCCTCACTCGGGCTCGGCCCGCTGGACACCGCCGAGGTGGCGGAGCTGACCGCC
CACTCCTTCCCGGAGCAGGACCCCCTGCCGTCGTTCGTCGGCCGCCTCCTCTCCGTGACC
GGCGGCAGCCCGCTGGAGATCGTCCGGCTCCTGCGCGACCTGCGCTCCGCCGGACTGGGC
CCCGACGACACCGGGACGGCACGCCTCGCCCAGGCCGGCGGGAAGGTCGTCGCCGCCTCC
GTCCGGGGTGTGCTGGAACACCAGCCGGACTGGGTGCGCCAGGTCGCGCGTGCCGTGGCC
GTGCTCGGCGACGAGGACCGGACGTACCTGGCCGCCCTCGGCAGGGTCTCCGTCGTCCAC
GTGGAGGAGGCCGTGGAGATCCTGCGCGACGCCGGGCTGATCCACCCCGGCCACCTGGAG
CTCTCCCACGACCTGGTGCGCGCCGCGGTCCTCGACGCCGTCGGCGCGTCGGGCGTCGCC
GTCCTGCGCAGACGCGCCGCCCGGCTCCTCAGCGACGTCGGACGGTCCCCCGAGGAGATC
GCCACGCAGCTGCTGCTGGTCCCGGGCACCCCCGACGACTGGGCGGTCTCCGTGCTCCGG
GACGCCGCCGCCCAGGCCGAACAGCGCGGCGCCTGTGAGGCCGCCGCCCGCTACCTGGAG
CGCGTCCGCGAGGCCGAGCCGAAGGACCCCGACGTCCTCTCCCGGCTCGGCAAGGCGCTG
GCCGAGACCGACCCGGCCCGCTCGGTGACCCTGCTGCACGAGGCCCACTCCCTGACCACG
GACGTCCGCGCCCGCGCCGCCACAGCGGTTCAGCTGGGCCTGACCTGCCTCGCCGTGCAG
CAGTCGCCGGACGGTGCCCGGGCCCTCACCGAGGCGCTGGACGCCCTCGACGCCGAGCTG
GGTCCCGAGCCCGAACCCGCCGACCGCGAACTGCGCACCCTCACGGAGTCGGCCCTGCTG
ATCGTGGGCTCCGACGAGAAGGCCACCCTGCCCGACATCCTGCGCCGGACCGAGGGCCTC
ACCCCGCAGCCGGGGGACACCCCCGCCCAGCGTCAGCAACTCGCCATGCTGAGTGTGCTC
TCCGCCGCCGAGGGCGGGGGAGCGGAGGAGACCGTGGGCCGGGCCCGCCGCGCGCTGCGC
GCCCCCGGGGTGCCGCTGGGCGTCTGGTCACTGCTGCCCACCTCGCTCGCCCTGTCGCTG
GCCGACGAGAACGAGGCCGCCGAGGAGGTCCTGGAGACCGTGCTGCGCGGCAGCGGCGAC
ACCGCCGCGGTCTGGACGTACGTGCTCGCGCTCTCCACCCGGTCGCTGTTCCGCCTGGAG
AACGGGGCGGTGCCGGACGCGATGGCCGACGCGCAGACCGCGCTGGAGATCCTCGGCCAG
GAACGCTGGGGCGACACCGCCACGATGCCGCACACGGCGTACGCCTCCGTCCTCACCGAG
CGGGGTGATCCGGGGCGCGCGCTGGAGGCGCTGGACGCCATCAAACGCCCCCACCTGGAC
CGGTTCGTCTGGGAGTACCACTGGTACCTGATGGCGCGTGGCCGGGCGCTTGCCGCCGAC
GGCGACCTGGACGGAGCCCTGCAGGTCTTCGGGTCCTGCGGCGCCTCGATGGCGGAGGCC
GGACTCACCAACCCGGTCCTCGCGCCGTGGTGGCTGGAGACGGCCTGTCTGCTGGGCGAG
GCCGGACGCGGCGAGGAGGCGGGGCGGGCCGCCGCGCACGGCACCCGGCTCGCCGAACGC
TGGGGCACCCGCCGGGCCCTGGGGTACGCCGCGCTCGCCCGGGGCGCGGCGGCGCGCGGC
ACGGCGCGCACCGGGGCGCTGCGGGAGGCGGTCGCCCTGCTGGCGGACTCGCCCGCGCGG
AGCGGGCACGCCCGCGGCCTGTTGCTGCTGGGACGCGCCCTGGTGGAGGACGGGGCCGTG
CGGGAGGGCCGGGAGCATCTACGGGAGGCCGTCGGGCTGGCCCGGCGGTGCGGGTGCGTC
GCCCTCGCCCGGCGCGCCCGCGACGAGCTGATCGCGGCCGGCGGACGGATGCGCGAGGTC
ACCGCCTCACCGCTGGACATGCTCACCGGCACCGAGCGCACCGTGGCCGGGCTGGTCGCC
TCGGGCGCCGGCAACCGCGAAGTGGCGGAATCCCTCTTCGTCACCGTGCGGACCGTGGAA
CTCCACCTCACCAGCGTCTACCGGAAACTGGGAGTCGCCCGCCGGGGCGATCTGACCGAG
GCCCTGCGCGAGGCCGGCGCCACCGCCCGGCCGGCTGCGGAGAGGCGGCCGGGACATGCG
AAGCGGAGAAATCCATAG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000792 Transcription regulator LuxR, C-terminal (Domain)
 [928-942]  4.79999776836274e-08 PR00038 [942-958]  4.79999776836274e-08 PR00038 [958-970]  4.79999776836274e-08 PR00038
PR00038   HTHLUXR
 [921-986]  PS50043
PS50043   HTH_LUXR_2
 [926-979]  7.90000000000001e-12 PF00196
PF00196   GerE
 [925-982]  8.90000829418053e-19 SM00421
SM00421   HTH_LUXR
 [942-969]  PS00622
PS00622   HTH_LUXR_1
IPR011990 Tetratricopeptide-like helical (Domain)
 [361-390]  3.8e-13 G3DSA:1.25.40.10 [433-534]  3.8e-13 G3DSA:1.25.40.10 [650-935]  2.4e-21 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [936-986]  8.80000000000003e-17 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
 [906-992]  2.70000183580794e-16 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP No significant hit
TMHMM No significant hit