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CDS information : Griseo_00070


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Organism
StrainJP95
Entry nameGriseorhodin A
Contig
Start / Stop / Direction6,920 / 8,485 / + [in whole cluster]
6,920 / 8,485 / + [in contig]
Location6920..8485 [in whole cluster]
6920..8485 [in contig]
TypeCDS
Length1,566 bp (521 aa)
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close this sectionAnnotation

Category5.1 general function
Productputative acyl-CoA carboxylase beta subunit
Product (GenBank)putative transcarboxylase component of acyl-CoA carboxylase GrhG
Gene
Gene (GenBank)grhG
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[12323376] A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A. (Chem Biol. , 2002)
Related Reference
ACC
O86517
PmId
[11526020] Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). (Appl Environ Microbiol. , 2001)
[12048195] Kinetic and structural analysis of a new group of Acyl-CoA carboxylases found in Streptomyces coelicolor A3(2). (J Biol Chem. , 2002)
ACC
O54028
PmId
[9428714] Methylmalonyl-CoA decarboxylase from Propionigenium modestum--cloning and sequencing of the structural genes and purification of the enzyme complex. (Eur J Biochem. , 1997)
ACC
Q9X4K7
PmId
[10589718] Genetic and biochemical characterization of the alpha and beta components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2). (Microbiology. , 1999)
[12048195] Kinetic and structural analysis of a new group of Acyl-CoA carboxylases found in Streptomyces coelicolor A3(2). (J Biol Chem. , 2002)

close this sectionSequence

selected fasta
>putative acyl-CoA carboxylase beta subunit [putative transcarboxylase component of acyl-CoA carboxylase GrhG]
MTTETAAASDPTAELAQLKQEAADGPDEQATARQHAKGKLTARERIDLLLDEGSFQEIEA
LRRHRASGFGLENKRPYTDGVVTGWGTVHGRTVFVYAHDFRIFGGALGEAHAAKIHKIMD
MALAAGAPLVSLNDGAGARIQEGVTALAGYGGIFRRNTLASGVIPQISVMLGPCAGGAAY
SPALTDFIFMVRGTSQMFITGPDVVKAVTGEEITQNGLGGADVHAAVSGVAAFAHDDEAA
CLEDVRFLLSLLPSNNRETAPHRAPDDPADRPTDALRDLVPANPNQAYDVRAVIEEIVDD
GEFFEIQPDWASNIVCALTRLDGHVTGVVANQPAAFAGVLDIHASEKAARFVQFCDAFSI
PLVTLVDVPGFLPGVDQEHGGVIRHGAKLLYAYCNATVPRVQLITRKAYGGAYIVMDSRS
IGADVSLAWPTNEIAVMGAEGAANVIFRREIAAADDPDAVRAQRIKQYRTELMHPYYAAE
RGLVDDVIDPAATRSALIGALAMLRPKYTDLPSRKHGNPPV
selected fasta
>putative acyl-CoA carboxylase beta subunit [putative transcarboxylase component of acyl-CoA carboxylase GrhG]
GTGACCACCGAGACCGCCGCCGCATCCGACCCGACCGCCGAACTCGCCCAGCTCAAACAG
GAGGCCGCCGACGGCCCCGACGAGCAGGCCACGGCCCGGCAGCACGCGAAGGGGAAGCTG
ACCGCGCGAGAGCGCATCGACCTGCTCCTCGACGAAGGCTCGTTCCAGGAGATCGAGGCC
CTGCGCAGACACCGCGCGAGCGGCTTCGGCCTGGAGAACAAACGCCCGTACACCGACGGT
GTCGTGACCGGCTGGGGAACGGTGCACGGGCGGACCGTGTTCGTGTACGCCCACGACTTC
CGGATCTTCGGCGGCGCCCTCGGCGAGGCGCACGCCGCCAAGATCCACAAGATCATGGAC
ATGGCGCTCGCGGCGGGGGCCCCGCTGGTGTCCCTGAACGACGGGGCGGGCGCGCGTATC
CAGGAGGGCGTCACCGCGCTGGCCGGCTACGGCGGCATCTTCCGCCGCAACACCCTCGCC
TCCGGGGTGATCCCGCAGATCTCCGTGATGCTCGGCCCGTGCGCCGGGGGCGCCGCGTAC
TCGCCCGCGCTCACCGACTTCATCTTCATGGTGCGCGGGACCTCGCAGATGTTCATCACC
GGACCGGACGTCGTCAAGGCGGTCACCGGCGAGGAGATCACCCAGAACGGACTGGGCGGG
GCCGACGTCCACGCGGCGGTGTCCGGTGTGGCGGCGTTCGCCCACGACGACGAGGCCGCC
TGCCTGGAGGACGTACGGTTCCTGCTCTCGCTGCTGCCGTCCAACAACCGCGAGACCGCT
CCGCACCGGGCCCCGGACGATCCGGCCGACCGCCCCACCGACGCCCTGCGGGACCTGGTC
CCCGCCAACCCCAACCAGGCGTACGACGTACGGGCGGTGATCGAGGAGATCGTCGACGAC
GGTGAGTTCTTCGAGATCCAGCCGGACTGGGCGTCCAACATCGTCTGCGCGCTGACCCGG
CTCGACGGGCATGTGACGGGCGTCGTCGCCAACCAGCCCGCCGCGTTCGCCGGGGTGCTC
GACATCCACGCCAGCGAGAAGGCGGCCCGCTTCGTGCAGTTCTGCGACGCGTTCTCGATC
CCGCTGGTGACCCTGGTCGACGTGCCCGGCTTCCTGCCGGGGGTGGACCAGGAGCACGGC
GGCGTCATCCGCCACGGCGCGAAGCTGCTCTACGCCTACTGCAACGCGACCGTTCCGCGC
GTGCAGTTGATCACGCGCAAGGCGTACGGCGGCGCGTACATCGTCATGGACTCCCGCTCC
ATCGGCGCGGACGTCTCGCTGGCCTGGCCGACGAACGAGATCGCGGTCATGGGCGCGGAG
GGGGCCGCCAACGTCATCTTCCGGCGGGAGATCGCCGCGGCGGACGACCCGGACGCCGTA
CGGGCCCAGCGGATCAAGCAGTACCGGACGGAGTTGATGCACCCGTACTACGCGGCCGAG
CGCGGCCTGGTGGACGACGTCATCGACCCGGCGGCGACCCGCTCCGCGCTCATCGGCGCG
CTCGCCATGCTCCGGCCCAAGTACACGGACCTGCCGTCCCGCAAGCACGGCAACCCCCCG
GTGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000022 Carboxyl transferase (Domain)
 [33-518]  PF01039
PF01039   Carboxyl_trans
IPR011762 Acetyl-coenzyme A carboxyltransferase, N-terminal (Domain)
 [14-228]  PS50980
PS50980   COA_CT_NTER
IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal (Domain)
 [229-513]  PS50989
PS50989   COA_CT_CTER
SignalP No significant hit
TMHMM No significant hit