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CDS information : Griseu_00030


close this sectionLocation

Organism
StrainK-63
Entry nameGriseusin
Contig
Start / Stop / Direction2,809 / 3,078 / + [in whole cluster]
2,809 / 3,078 / + [in contig]
Location2809..3078 [in whole cluster]
2809..3078 [in contig]
TypeCDS
Length270 bp (89 aa)
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close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase acyl carrier protein subunit
Product (GenBank)acyl carrier protein
Gene
Gene (GenBank)
EC number
Keyword
  • type II PKS
Note
Note (GenBank)
  • ORF3
Reference
ACC
PmId
[8169211] Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus. (J Bacteriol. , 1994)
[9108302] Post-translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins. (FEBS Lett. , 1997)
[9738947] Acylation of Streptomyces type II polyketide synthase acyl carrier proteins. (FEBS Lett. , 1998)
Related Reference
ACC
Q56165
NITE
Jado_00100
PmId
[7881555] Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230. (Microbiology. , 1994)
[9224566] Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides. (Chem Biol. , 1997)

close this sectionPKS/NRPS Module

ACP7..80

close this sectionSequence

selected fasta
>polyketide synthase acyl carrier protein subunit [acyl carrier protein]
MSKQEFTLEDLKRILLEGAGADEGVDLDGDILDTDFEELGYESLALLETGGRIEREYGIT
LDDDVLADSRTPRSLIAAINAAFQGLVEA
selected fasta
>polyketide synthase acyl carrier protein subunit [acyl carrier protein]
GTGTCCAAGCAGGAGTTCACCCTCGAAGACCTCAAGCGCATCCTTCTGGAAGGCGCCGGC
GCGGACGAGGGCGTCGACCTCGACGGCGACATCCTCGACACCGATTTCGAGGAACTCGGC
TACGAGTCGCTGGCGTTGCTGGAGACCGGCGGCCGGATCGAGCGCGAGTACGGGATCACG
CTCGACGACGACGTGCTCGCCGACAGCCGCACGCCGCGCTCGCTGATAGCCGCCATCAAC
GCCGCGTTCCAGGGCCTCGTCGAGGCCTGA
ACP7..80
ACP19..240

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR006162 Phosphopantetheine attachment site (PTM)
 [38-53]  PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
 [3-82]  8.80000265836278e-15 SSF47336
SSF47336   ACP_like
 [4-82]  7.59999999999998e-17 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
 [31-79]  6.40000000000001e-10 PF00550
PF00550   PP-binding
 [7-80]  PS50075
PS50075   ACP_DOMAIN
SignalP
 [1-21]  0.059 Signal
Eukaryota   
TMHMM No significant hit