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CDS information : Heda_00220


close this sectionLocation

Organism
StrainATCC 15422
Entry nameHedamycin
Contig
Start / Stop / Direction32,368 / 31,640 / - [in whole cluster]
32,368 / 31,640 / - [in contig]
Locationcomplement(31640..32368) [in whole cluster]
complement(31640..32368) [in contig]
TypeCDS
Length729 bp (242 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productputative NDP-hexose N,N-dimethyltransferase
Product (GenBank)N,N-dimethyltransferase
GenehedH
Gene (GenBank)
EC number2.1.1.-
Keyword
Note
Note (GenBank)
  • orf11
Reference
ACC
PmId
[15271354] The hedamycin locus implicates a novel aromatic PKS priming mechanism. (Chem Biol. , 2004)
Related Reference
ACC
Q9ZGH6
NITE
Pikro_00100
PmId
[9770448] A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. (Proc Natl Acad Sci U S A. , 1998)
[12119032] Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine. (Biochemistry. , 2002)

close this sectionSequence

selected fasta
>putative NDP-hexose N,N-dimethyltransferase [N,N-dimethyltransferase]
MYGTEFAEIYDLVYAARGKDYAGECAEVVRHVRARRPDAASLLDVACGTGAHLALLRDEF
AVVEGLELSEHMIARARAGLPDVPVHQGDMRGFRTGRAYDALTCMFSSIGYVGSPEDLGR
ALSSMARHLTPGGVLVLEPWYFPEAFLPEYIADDLVRTGDRVVARVSYSAREGDRVPIVV
HYVDALKGRGIRHFTDVHRMSLFTREQYRTAFERAGCSVEYVEGGPFRCGLFVGVREDGP
PA
selected fasta
>putative NDP-hexose N,N-dimethyltransferase [N,N-dimethyltransferase]
GTGTACGGAACGGAGTTCGCCGAGATCTACGACCTGGTCTACGCCGCGCGCGGCAAGGAC
TACGCCGGCGAGTGCGCGGAGGTGGTGCGGCATGTGCGGGCACGCCGCCCGGACGCCGCC
TCCCTGCTGGACGTGGCGTGCGGAACGGGTGCCCATCTGGCCCTGCTGCGGGACGAGTTC
GCGGTGGTGGAGGGGCTCGAACTGTCCGAGCACATGATCGCCCGGGCGCGGGCCGGCCTG
CCGGACGTGCCGGTCCACCAGGGCGACATGCGCGGCTTCCGCACCGGTCGCGCGTACGAC
GCGCTCACGTGCATGTTCAGCTCCATCGGGTACGTCGGCTCGCCGGAGGACCTCGGCCGG
GCGCTGAGCAGCATGGCGCGGCATCTGACGCCCGGCGGGGTGCTGGTCCTCGAACCCTGG
TACTTCCCCGAGGCGTTCCTGCCCGAGTACATCGCGGACGACCTGGTCCGGACGGGGGAC
CGGGTCGTGGCGCGGGTGTCGTACTCGGCGCGGGAGGGCGACCGGGTGCCGATCGTGGTG
CACTACGTCGACGCCCTCAAGGGCCGCGGCATCCGGCACTTCACGGACGTGCACCGCATG
AGCCTGTTCACGCGGGAGCAGTACCGGACCGCCTTCGAGCGGGCGGGCTGCTCCGTGGAG
TACGTCGAGGGCGGCCCGTTCCGCTGCGGTCTCTTCGTCGGCGTGCGCGAAGACGGGCCG
CCGGCGTAG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
No significant hit
SignalP
 [1-34]  0.041 Signal
Bacteria, Gram-negative   
 [1-15]  0.074 Signal
Eukaryota   
TMHMM No significant hit