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Herb_00290 Herb_00290   last last

CDS information : Herb_00300


close this sectionLocation

Organism
StrainAM 3672
Entry nameHerbimycin A
Contig
Start / Stop / Direction85,764 / 82,921 / - [in whole cluster]
85,764 / 82,921 / - [in contig]
Locationcomplement(82921..85764) [in whole cluster]
complement(82921..85764) [in contig]
TypeCDS
Length2,844 bp (947 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative LuxR family transcriptional regulator
Product (GenBank)HbmRI
Gene
Gene (GenBank)hbmRI
EC number
Keyword
Note
Note (GenBank)
  • putative transcriptional regulator; LuxR-type
Reference
ACC
PmId
[16085885] Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption. (Appl Environ Microbiol. , 2005)
Related Reference
ACC
Q06BL2
NITE
Gelda_00130
PmId
[18214443] The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997. (Arch Microbiol. , 2008)

close this sectionSequence

selected fasta
>putative LuxR family transcriptional regulator [HbmRI]
MSMGLTDYQSELRGVLDMAARGNGGLLKVTGGPGVGKTSLLGSLKEQAAESGAVCLMASG
FADDTAIPFNIVEQLIWSSAFTDELDVVARWRTAGERYSEAEPGILRSLVREISDVLHRI
AGGKQLIIAVDDAEHADYPSLMCLLHIARHASGTRTLVVMTCGQSHQLCVGTHGFHELYK
IKIDTLPESGVGHLLERHGDADLADRIRASCHAVSGGNPRLVKALLRDHLQAAPGGSETD
VTVGAEFQETYRGCLLSHPALLQVAQALAVLDRYGGPGRVASLLACGRERATRAITVMNS
AGLLEDGRFRHPAARYITLETLSAEDRARLSAKAAELLYADGADPIAVAELLVTADRTPD
QKDVTVLWHAAQKNLDHGRTEEAIAGLRLAARADLGRREHMDILMALVGALWSSNPATAE
PELDRLMAAIREEFPADIPEQYLCFLLFMVLWFGRFSDGEEAFKWLSGGGDTDNASSMAA
LRVTRQWATFLKPALIHDFPDQASSAGEVDGLWAANLEHGLQLSVDELGMEIGHFQDPRQ
VADFSPDTMHLLSPSNHFWFAYAYACRMVWALAARGEAETADRLCGALFTAAGNLNMKTP
GAVALAMRAYIRCRHGDFTSAIDLAGTALKSIPPRGWGVAIGLPLSVLVAAHTAIGRLDE
AQRYLHYWVPKEMFDSVVGLEYLRARGQYCLATNRPYAALNDFMVSGMLMDQWPVDFGDL
APWRIDAAEAYLRVQEPAEAKRLALEELKLSPDRPLSTRGRALRVLAMAEDPDKRRLLLY
QSAKCLREHGDRFELARTLAELSQDFLSTGETQQARGTWHEAQKLMDECGISAQHESRRD
LVVDGAESPADARLPEPAGDTGEPEESDPAASAEGAEQPVLSEAEWRVATLAASGMSNRQ
IAKSLYITVSTVEQHLTRIYRKLSVGNRQELSRRLWQLIGATGSSSC
selected fasta
>putative LuxR family transcriptional regulator [HbmRI]
ATGAGTATGGGACTGACAGATTATCAATCAGAGCTTCGCGGCGTCCTCGACATGGCAGCA
CGAGGAAACGGCGGGCTTCTCAAAGTGACCGGGGGACCCGGTGTCGGAAAGACCTCCTTA
TTGGGCAGTCTGAAGGAGCAGGCGGCCGAATCGGGTGCGGTCTGTCTTATGGCGTCCGGA
TTCGCGGACGACACCGCGATCCCGTTCAATATAGTGGAACAGCTCATCTGGTCGTCCGCG
TTCACGGATGAATTGGACGTCGTGGCGCGCTGGAGGACCGCCGGAGAGCGGTATTCGGAA
GCCGAACCCGGCATACTGAGAAGCCTGGTCCGAGAGATATCCGATGTGCTGCACCGCATC
GCGGGCGGCAAGCAACTGATCATCGCGGTTGACGATGCCGAGCATGCCGACTACCCCTCC
CTCATGTGCCTGCTGCATATCGCCAGGCATGCCTCCGGCACCCGTACGCTCGTCGTGATG
ACCTGCGGGCAGAGTCATCAGTTGTGTGTCGGCACTCACGGCTTCCATGAGCTCTACAAG
ATCAAGATCGATACACTCCCGGAATCCGGGGTCGGACACCTGCTGGAGCGGCACGGCGAC
GCCGACCTGGCCGACCGGATCCGCGCCTCCTGCCACGCCGTCAGCGGTGGCAACCCACGG
CTGGTCAAGGCCCTGCTGCGGGACCATCTCCAGGCCGCTCCGGGCGGGTCGGAGACGGAT
GTCACCGTCGGCGCGGAGTTCCAGGAGACCTATCGCGGGTGCCTGTTGTCCCATCCGGCG
TTGCTCCAGGTGGCACAGGCCCTCGCGGTGCTGGACCGGTACGGCGGCCCGGGGCGGGTG
GCCAGTCTGCTCGCCTGCGGCCGGGAACGCGCGACCCGGGCCATCACCGTCATGAACTCC
GCCGGACTGCTGGAGGACGGACGGTTCCGGCACCCCGCGGCGCGATACATCACGCTGGAG
ACGCTGTCGGCGGAGGACCGGGCCCGGCTCAGCGCGAAAGCGGCCGAACTTCTGTATGCC
GACGGGGCCGATCCGATCGCGGTGGCGGAACTCCTGGTCACCGCCGACAGAACGCCCGAC
CAAAAAGACGTCACCGTGCTCTGGCACGCGGCCCAGAAGAATCTCGACCACGGCCGTACG
GAGGAAGCGATCGCGGGCCTGCGGCTCGCCGCCCGCGCGGACCTCGGCCGGCGCGAGCAC
ATGGACATTCTCATGGCGCTGGTCGGCGCGTTATGGTCCAGCAATCCGGCGACCGCCGAA
CCCGAACTGGACCGCCTGATGGCCGCGATACGGGAGGAATTCCCCGCGGACATCCCGGAA
CAGTATCTGTGCTTCCTGCTCTTCATGGTGCTCTGGTTCGGCCGGTTCAGCGATGGGGAA
GAAGCCTTCAAGTGGCTTTCGGGCGGTGGTGACACCGATAACGCCTCCAGCATGGCCGCT
CTGCGGGTGACCCGGCAGTGGGCCACCTTCCTCAAACCGGCCCTGATCCATGACTTCCCC
GACCAGGCTTCCTCGGCCGGGGAAGTCGACGGACTGTGGGCGGCCAACCTGGAGCACGGT
CTTCAGCTCTCCGTCGACGAACTGGGCATGGAGATCGGGCATTTCCAGGATCCCCGGCAG
GTGGCGGACTTCTCTCCCGACACCATGCATCTGTTGTCGCCCTCCAACCACTTCTGGTTC
GCCTACGCATACGCCTGCCGGATGGTCTGGGCATTGGCCGCGAGAGGCGAAGCGGAAACG
GCGGACCGGCTGTGCGGCGCGCTTTTCACCGCGGCCGGCAACTTGAACATGAAGACGCCC
GGCGCCGTCGCCCTGGCCATGCGCGCCTACATCAGATGCCGCCATGGGGACTTCACCTCG
GCCATCGATCTCGCCGGCACCGCGCTGAAGTCCATCCCCCCGCGCGGCTGGGGCGTCGCC
ATCGGATTGCCGCTCTCCGTTCTGGTGGCGGCCCACACCGCCATCGGCAGACTCGATGAG
GCCCAGCGATATCTGCATTACTGGGTGCCGAAGGAAATGTTCGACAGCGTTGTCGGGTTG
GAGTACCTCCGGGCCCGTGGACAGTACTGCCTGGCCACCAACCGCCCCTACGCAGCGCTG
AACGACTTCATGGTGAGCGGGATGCTGATGGACCAGTGGCCCGTGGACTTCGGCGACCTG
GCGCCCTGGCGTATCGACGCCGCCGAGGCGTATCTGCGTGTCCAGGAGCCGGCGGAGGCC
AAAAGACTCGCCCTGGAGGAACTCAAGCTGTCGCCCGACCGCCCCTTGAGCACCCGCGGC
CGGGCGCTGCGCGTTCTGGCCATGGCCGAAGACCCGGACAAGCGCAGGCTGCTCCTGTAT
CAGTCCGCCAAGTGTCTGCGCGAGCACGGCGACCGTTTCGAACTCGCCCGTACGCTCGCC
GAGCTCAGCCAGGACTTCCTCAGCACCGGGGAAACCCAGCAGGCCCGCGGCACCTGGCAT
GAGGCGCAGAAGCTGATGGACGAGTGCGGGATCAGCGCCCAGCACGAGAGCCGCAGGGAC
CTCGTCGTGGATGGCGCCGAGAGCCCCGCGGACGCGCGACTGCCGGAACCCGCCGGGGAT
ACCGGGGAGCCCGAGGAGTCGGACCCCGCCGCCTCGGCCGAAGGCGCGGAGCAGCCCGTT
CTCTCGGAGGCCGAGTGGCGCGTGGCGACCCTGGCCGCGTCGGGGATGTCCAACCGGCAG
ATCGCCAAGAGCCTCTACATCACGGTCAGCACCGTGGAGCAGCATCTGACCCGCATCTAC
CGAAAGCTCTCGGTCGGAAATCGGCAGGAGCTGTCGCGTCGGCTGTGGCAGCTCATCGGA
GCCACCGGATCGTCCTCCTGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000792 Transcription regulator LuxR, C-terminal (Domain)
 [895-922]  PS00622
PS00622   HTH_LUXR_1
 [878-935]  2.30000440726534e-21 SM00421
SM00421   HTH_LUXR
 [881-895]  1.49999977583352e-08 PR00038 [895-911]  1.49999977583352e-08 PR00038 [911-923]  1.49999977583352e-08 PR00038
PR00038   HTHLUXR
 [874-939]  PS50043
PS50043   HTH_LUXR_2
 [879-932]  8.60000000000001e-14 PF00196
PF00196   GerE
IPR011990 Tetratricopeptide-like helical (Domain)
 [572-840]  1.7e-14 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [877-937]  2.90000000000001e-19 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
 [859-938]  1.89999859865864e-16 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP No significant hit
TMHMM No significant hit
Herb_00290 Herb_00290   last last