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CDS information : Kirro_00310


close this sectionLocation

Organism
StrainTü365
Entry nameKirromycin
Contig
Start / Stop / Direction91,056 / 92,255 / + [in whole cluster]
91,056 / 92,255 / + [in contig]
Location91056..92255 [in whole cluster]
91056..92255 [in contig]
TypeCDS
Length1,200 bp (399 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.3 modification reduction
Productputative cytochrome P450
Product (GenBank)putative cytochrome P450 hydroxylase
Gene
Gene (GenBank)kirOI
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[18291322] Molecular analysis of the kirromycin biosynthetic gene cluster revealed beta-alanine as precursor of the pyridone moiety. (Chem Biol. , 2008)
Related Reference
ACC
A6YRR3
PmId
[19376895] Characterization of P450 FcpC, the enzyme responsible for bioconversion of diosgenone to isonuatigenone in Streptomyces virginiae IBL-14. (Appl Environ Microbiol. , 2009)

close this sectionSequence

selected fasta
>putative cytochrome P450 [putative cytochrome P450 hydroxylase]
MSETVRPVDGLPMTRGTCPFDPAPELAELREEQPVARMVFPDGHLGWLITGYDEVRRLLA
ARGMSSRGDLLRTPIPLPMAGNRTELAPGMFTAMDPPEHTHYRRRLTAWFSARRTRTMEP
RLTEHVDLYLGRMIEEGGPTDLVAAFAEPVAGLVICELLGVPADRRDVFVKGIKALLTVH
SSAEEAIAGWQNVGGQLMELIRAKREEPTDDLLGTLVSDGAFSDEELATIGSVLLVGGYD
TSKNMIALGTFALLAHPDQYAALAADPGLGAGAVEELLRYVTVMHAGSIRAAGADMDFDG
HHFTEGDAVSLSLAAANRDPSLCEDPDRLDITRPPVAHLSFGYGIHQCVGQQLARLELRI
AFEGLARRLPGLRLAIPEDQVRTNPESIIYGVHELPVTW
selected fasta
>putative cytochrome P450 [putative cytochrome P450 hydroxylase]
GTGTCCGAGACCGTTCGTCCCGTCGACGGCCTGCCCATGACCCGTGGCACGTGCCCGTTC
GACCCCGCACCCGAGCTCGCCGAGCTGCGCGAGGAGCAGCCGGTGGCCCGCATGGTCTTC
CCGGACGGCCACCTCGGCTGGCTGATCACCGGCTACGACGAGGTCCGCCGGCTCCTCGCC
GCCCGGGGCATGAGCTCGCGCGGCGACCTGCTGCGCACGCCGATCCCGCTGCCGATGGCC
GGGAACCGGACCGAACTGGCGCCGGGGATGTTCACGGCGATGGACCCGCCGGAGCACACC
CACTACCGGCGCCGGCTGACCGCCTGGTTCTCGGCCCGCCGCACCCGGACGATGGAGCCG
AGGCTGACCGAGCACGTCGACCTGTATCTCGGCAGGATGATCGAGGAAGGCGGACCCACC
GACCTGGTCGCCGCGTTCGCCGAGCCGGTCGCCGGGCTGGTGATCTGCGAGCTGCTCGGT
GTTCCCGCCGACCGGCGGGACGTGTTCGTCAAGGGCATCAAGGCGCTGCTGACCGTCCAC
TCCAGCGCGGAGGAGGCGATCGCCGGCTGGCAGAACGTGGGCGGGCAGCTGATGGAGCTG
ATCCGCGCCAAACGCGAGGAGCCCACCGACGACCTGCTCGGCACGCTGGTCTCCGACGGC
GCTTTCAGCGACGAGGAGCTGGCGACCATCGGCAGCGTGCTGCTCGTGGGCGGCTACGAC
ACCAGCAAGAACATGATCGCGCTGGGCACCTTCGCCCTGCTGGCACACCCCGACCAGTAC
GCGGCGCTGGCCGCGGACCCGGGCCTGGGCGCGGGCGCGGTGGAGGAACTGCTGCGTTAC
GTGACGGTCATGCACGCCGGCTCGATCCGCGCGGCCGGCGCCGACATGGACTTCGACGGG
CACCACTTCACCGAGGGAGACGCCGTGTCCCTGTCGCTGGCCGCGGCCAACCGGGACCCG
TCGCTCTGCGAGGACCCGGACCGCCTGGACATCACCCGGCCGCCGGTGGCGCACCTGTCG
TTCGGTTACGGCATCCACCAGTGCGTCGGCCAGCAACTGGCCCGCCTTGAGCTGCGGATC
GCGTTCGAGGGGCTGGCCCGGCGGCTGCCCGGGCTGCGGCTGGCGATCCCCGAGGACCAG
GTCCGCACCAACCCCGAATCGATCATCTACGGCGTCCACGAGCTGCCGGTGACATGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001128 Cytochrome P450 (Family)
 [237-254]  5.09999882439977e-06 PR00385 [272-283]  5.09999882439977e-06 PR00385 [339-348]  5.09999882439977e-06 PR00385 [348-359]  5.09999882439977e-06 PR00385
PR00385   P450
 [17-399]  5.00000000000001e-94 G3DSA:1.10.630.10
G3DSA:1.10.630.10   Cyt_P450
 [273-365]  1.6e-14 PF00067
PF00067   p450
 [7-399]  2.0000139277205e-88 SSF48264
SSF48264   Cytochrome_P450
IPR002397 Cytochrome P450, B-class (Family)
 [94-105]  4.30000170645869e-48 PR00359 [141-157]  4.30000170645869e-48 PR00359 [158-173]  4.30000170645869e-48 PR00359 [195-217]  4.30000170645869e-48 PR00359 [272-283]  4.30000170645869e-48 PR00359 [290-317]  4.30000170645869e-48 PR00359 [318-333]  4.30000170645869e-48 PR00359 [339-348]  4.30000170645869e-48 PR00359 [348-359]  4.30000170645869e-48 PR00359
PR00359   BP450
IPR017972 Cytochrome P450, conserved site (Conserved_site)
 [341-350]  PS00086
PS00086   CYTOCHROME_P450
SignalP No significant hit
TMHMM No significant hit