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CDS information : MUP_00210

Location

Organism	Mycobacterium ulcerans
Strain	Agy99
Entry name	Mycolactone
Contig	BX649209
Start / Stop / Direction	16,609 / 16,872 / + [in whole cluster] 16,609 / 16,872 / + [in contig]
Location	16609..16872 [in whole cluster] 16609..16872 [in contig]
Type	CDS
Length	264 bp (87 aa)

Annotation

Category
Product
Product (GenBank)	possible transcriptional regulatory protein
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	MUP021, -, len: 87 aa. Possible transcriptional regulatory protein, similar to other possible WhiB-like regulatory proteins e.g. O69649\|Rv3681c Probable whiB4 from M. tuberculosis (118 aa), fasta scores: opt: 141, E(): 0.001, (44.681% identity in 47 aa overlap); P96215\|Rv3862c Possible whiB6 from M. tuberculosis (116 aa), fasta scores: opt: 133, E(): 0.0054, (29.412% identity in 85 aa overlap). Also weakly similar to other putative regulatory proteins e.g. Q9S2B9 Putative regulatory protein from Streptomyces coelicolor (112 aa), fasta scores: opt: 115, E(): 0.11, (34.211% identity in 76 aa overlap). Contains a Pfam match to entry PF02467 Transcription factor WhiB.

Sequence

>[possible transcriptional regulatory protein]
MTAANPVKLGVGLCVYDDEDKWFSGYSSNRKAAAICANCPIIVSCAERALRLQVTDGVWV
TVVMPGSRHTDALEQARARLRRVIEHY

>[possible transcriptional regulatory protein]
ATGACCGCGGCGAACCCCGTAAAACTCGGTGTCGGCCTTTGCGTGTATGACGACGAAGAC
AAGTGGTTCAGCGGCTACAGTTCCAATCGAAAAGCGGCTGCGATCTGTGCGAACTGCCCG
ATCATCGTCAGCTGCGCCGAGAGGGCTCTTCGGCTGCAAGTCACCGACGGTGTCTGGGTA
ACGGTGGTCATGCCCGGTTCACGTCACACCGATGCTCTCGAGCAAGCGCGTGCACGCCTG
CGTCGAGTTATCGAGCACTACTGA

Feature

BLASTP Database:UniProtKB:2010_04	show BLAST table
InterPro Database:interpro:26.0	IPR003482 Transcription factor WhiB (Family) PF02467 Whib
SignalP	No significant hit
TMHMM	No significant hit

MUP_00200 MUP_00220

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