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MUP_00380 MUP_00380   MUP_00400 MUP_00400

CDS information : MUP_00390


close this sectionLocation

Organism
StrainAgy99
Entry nameMycolactone
Contig
Start / Stop / Direction86,312 / 79,080 / - [in whole cluster]
86,312 / 79,080 / - [in contig]
Locationcomplement(79080..86312) [in whole cluster]
complement(79080..86312) [in contig]
TypeCDS
Length7,233 bp (2,410 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)Type I modular polyketide synthase
Gene
Gene (GenBank)mlsA2
EC number
Keyword
Note
Note (GenBank)
  • MUP039c, mlsA2, len: 2410 aa. Type I modular polyketide synthase, composed of one extender module (module 9); required for the synthesis of the mycolactone core in M. ulcerans (see Stinear et al., 2003). Similar to part of several e.g. Q9S0R8 Type I polyketide synthase AVES 1 from Streptomyces avermitilis (3972 aa), fasta scores: opt: 3342, E(): 2.1e-187, (40.556% identity in 2160 aa overlap); Q93NW8 AmphA from Streptomyces nodosus (1412 aa), fasta scores: opt: 3171, E(): 9.9e-178, (47.163% identity in 1304 aa overlap). Contains a Pfam match to entry PF00109 ketoacyl-synt: Beta-ketoacyl synthase, N-terminal domain and a Pfam match to entry PF02801 ketoacyl-synt_C: Beta-ketoacyl synthase, C-terminal domain. Contains a Pfam match entry PF00550 pp-binding: Phosphopantetheine attachment site and a Pfam match to entry PF00698 Acyl_transf: Acyl transferase domain.
Reference
ACC
PmId
[14736915] Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. (Proc Natl Acad Sci U S A. , 2004)
[18493665] The unusual macrocycle forming thioesterase of mycolactone. (Mol Biosyst. , 2008)

close this sectionPKS/NRPS Module

A9 malonyl-CoA
KS35..408
AT590..912
DH955..1128
ER1470..1773
KR1783..1963
ACP2063..2133

close this sectionSequence

selected fasta
>polyketide synthase [Type I modular polyketide synthase]
MVSTEENLRVYLKQVITDLHQMQARLRKIEKQRSERVAVVGMACRFPGGVASADQLWDLV
IAGRDVVGNFPADRGWDVEGLFDPDPDAVGKTYTRYGAFLDDAAGFDAGFFGISPREARA
MDPQQRLLLEVCWEALETAGIPAHTLAGTSTGVFVGAWAQSYGATNSDGAEGYAMTGGST
SVMSGRIAYTLGLEGPAITVDTACSSSLVAIHLACQSLRNNESQLALAGGVTVMSTPAVF
TEFSRQRGLAPDGRCKAFAATADGTGWGEGAAVLVLERLSEARRNNHPVLAIVAGSAINQ
DGASNGLTAPHGPSQQRVINQALANAGLTHDQVDAVEAHGTGTTLGDPIEASALHATYGH
HHTPDQPLWLGSIKSNIGHTQAAAGAAGVVKMIQAITHATLPATLHVDQPSPHIDWSSGT
VRLLTEPIQWPNTDHPRTAAVSSFGISGTNAHLILQQPPTPDTTQTPNTTTGSDPAVGSD
SAVGSDPAVGVLVWPLSARSAPGLSAQAARLYQHLSAHPDLDPIDVAHSLATTRSHHPHR
ATITTSIEHHSENNHDTTDALAALHALANNGTHPLLSRGLLTPQGPGKTVFVFPGQGSQY
PGMGADLYRQFPVFAHALDEVAAALNPHLDVALLEVMFSQQDTAMAQLLDQTFYAQPALF
ALGTALHRLFTHAGIHPDYLLGHSIGELTAAYAAGVLSLQDAATLVTSRGRLMQSCTPGG
TMLALQASEAEVQPLLEGLDHAVSIAAINGATSIVLSGDHDSLEQIGEHFITQDRRTTRL
QVSHAFHSPHMDPILEQFRQIAAQLTFSAPTLPILSNLTGQIARHDQLASPDYWTQQLRN
TVRFHDTVAALLGAGEQVFLELSPHPVLTQAITDTVEQAGGGGAAVPALRKDRPDAVAFA
AALGQLHCHGISPSWNVLYCQARPLTLPTYAFQHQRYWLLPTAGDFSGANTHAMHPLLDT
ATELAENRGWVFTGRISPRTQPWLNEHAVESAVLFPGTGFVELALHVADRAGYSSVNELI
VHTPLLLAGHDTADLQITVTDTDDMGRQSLNIHSHPHIGHDNTTTGDEQPEWVLHASAVL
TAQTTDHNHLPLTPVPWPPPGTAAIEVDDFYDDLAAQGYNYGPTFQGVQRIWRDHATPDV
IYAEVELPEDTDIDGYGIHPALFDAALHPLLALTQPPTNDTDDTNTADTGDQVRLPYAFT
GISLHATHATRLRVRLTRTGADAITVHTSDTTGAPVAIIDSLITRPLTTATGSAPATTAA
GLLHLSWPPHPDTTTDTDTDTDALRYQVIAEPTQQLPRYLHDLHTSTDLHTSTTEADVVV
WPVPVPSNEELQAHQASDTAVSSRIHTLTRQTLTVVQDWLTHPDTTGTRLVIVTRHGVST
SAHDPVPDLAHAAVWGLIRSAQNEHPGRFTLLDTDDNTNSDTLTTALTLPTRENQLAIRR
DTIHIPRLTRTAVLTPPDSGPWRLDTTGKGDLANLALLPTAHTALASGQIRIDVRAAGLN
FHDVVVALGLIPDDGFGGEAAGVISEIGPDVYGFAVGDAVTGMTVSGAFAPSTVADHRMV
MTIPARWSFPQAASIPVVFLTAYIALAEISGLSRGQRVLIHAGTGGVGMAAIQLAHHLGA
EVFATASAAKWSTLEALGVPRDHIASSRTLDFSNAFLDATNGAGVDVVLNCLSGEFVEAS
LALLPRGGHFVEIGKTDIRDTEVIAATHPGVIYRALDLLSVSPDHIQRTLAQLSPLFATD
TLKPLPTTNYSIYQAISALRDMSQARHTGKIVLTAPVVVDPEGTVLITGGTGTLGALFAE
HLVSAHGVRHLLLTSRRGPQAHGATDLQQRLTDLGAHVTITACDISDPEALAALVNSVPT
QHRLTAVVHTAAVLADTPVTELTGDQLDQVLAPKIDAAWQLHQLTYEHNLSAFIMFSSMA
GMIGSPGQGNYAAANTALDALADYRHRLGLPATSLAWGYWQTRTGVTAHLTDVDLARMTR
LGLMPIATSHGLALFDAALATGQPVSIPAPINTHTLARHARDNTLTPILSALITTPRRRA
ASAATDLAARLNGLSPQQQQQTLATLVAAATATVLGHHTPESISPATAFKDLGIDSLTAL
ELRNTLTHNTGLDLPPTLIFDHPTPHALTQHLHTRLTQSHTPVGPIASLLSHAIDEGKFR
AGADLLMAASNLNQSFSNMAELNQLPAVTDIADASPDGLLTLICISTSENEYARLAAANI
HSLTFAEIAAPGFYDAQLPNSIETSAEALATAITGAYANTSIVLVAHSIVCELAQATMTR
LQDADIDLVGLVLLDPLEGTNSTEDYVETVLTRIEHINAPRVGVDGYLAALGRYLQFHED
RRIPIPETRHMTLHSDTKIDRAQTPMNLLQDEAALTALKIGNWMNDTGSIAVTLRDGPVF
LGRARSVNMR
selected fasta
>polyketide synthase [Type I modular polyketide synthase]
GTGGTGTCAACTGAAGAAAACCTACGCGTTTACTTAAAACAGGTCATCACAGACCTCCAC
CAAATGCAGGCACGTCTGCGGAAGATCGAAAAGCAGAGATCAGAGCGGGTGGCGGTGGTG
GGGATGGCGTGTCGTTTCCCCGGTGGTGTCGCATCAGCGGATCAGTTGTGGGACTTGGTG
ATCGCTGGCCGTGATGTGGTGGGTAATTTTCCGGCCGATCGGGGTTGGGATGTGGAGGGA
CTGTTTGATCCCGATCCGGACGCGGTCGGCAAAACCTACACCCGTTACGGCGCGTTCCTT
GACGATGCGGCAGGTTTTGATGCCGGGTTCTTTGGGATCTCTCCACGGGAGGCACGCGCG
ATGGACCCCCAGCAGCGGCTGCTGCTGGAGGTGTGCTGGGAAGCGCTAGAAACCGCGGGT
ATTCCCGCGCACACCTTGGCCGGCACCTCCACCGGGGTATTCGTCGGAGCCTGGGCCCAG
TCCTACGGCGCCACCAACTCCGATGGCGCTGAGGGGTATGCGATGACCGGCGGCTCGACT
AGCGTCATGTCCGGCCGTATCGCCTACACCTTGGGCCTAGAAGGTCCAGCGATCACCGTT
GACACCGCCTGCTCGTCATCGCTGGTGGCAATTCACCTGGCCTGCCAATCCTTACGCAAC
AACGAATCCCAGCTAGCACTGGCCGGCGGCGTCACCGTGATGAGCACACCTGCGGTTTTC
ACCGAGTTCTCCCGCCAACGCGGCCTGGCCCCAGATGGACGCTGCAAAGCCTTCGCCGCT
ACCGCCGATGGCACCGGCTGGGGTGAAGGCGCCGCGGTCTTGGTCCTTGAACGGCTCTCC
GAGGCCCGCCGCAACAACCACCCGGTCCTTGCGATCGTCGCTGGATCGGCGATCAACCAA
GACGGCGCATCCAACGGACTGACCGCACCCCACGGCCCGTCACAACAACGCGTCATCAAC
CAAGCACTAGCCAACGCCGGCCTCACCCACGACCAGGTCGACGCCGTCGAAGCCCACGGC
ACCGGCACCACACTGGGTGACCCCATCGAAGCCAGCGCCCTACACGCCACCTACGGCCAC
CACCACACGCCCGATCAACCGCTTTGGCTGGGATCCATCAAATCCAACATCGGCCACACC
CAAGCCGCCGCCGGCGCCGCCGGTGTGGTCAAGATGATCCAAGCCATCACCCACGCCACC
TTGCCCGCCACCTTGCACGTCGACCAACCCAGCCCCCACATCGACTGGTCCAGCGGCACA
GTCCGACTCCTAACCGAGCCCATCCAATGGCCCAACACCGACCACCCCCGCACCGCGGCG
GTGTCCTCATTCGGCATCAGCGGCACCAACGCCCACCTCATCCTCCAACAACCCCCCACC
CCCGACACCACACAAACCCCCAACACCACAACAGGTTCTGATCCCGCAGTGGGTTCTGAT
TCCGCAGTGGGTTCTGATCCCGCAGTGGGTGTACTGGTGTGGCCGTTGTCAGCGCGTTCA
GCGCCGGGGTTAAGCGCACAAGCGGCCCGTCTGTACCAGCATCTCAGCGCCCACCCCGAT
CTGGATCCGATCGATGTAGCCCACAGCCTGGCTACCACACGCAGCCACCACCCCCACCGC
GCCACCATCACCACCAGCATTGAGCACCACAGCGAAAACAACCACGACACAACCGATGCG
CTGGCCGCACTGCACGCCCTGGCCAACAACGGCACACACCCCCTGCTGAGCAGAGGCCTG
CTGACCCCACAGGGCCCCGGCAAAACAGTGTTCGTGTTCCCCGGACAGGGCAGTCAATAC
CCCGGCATGGGCGCAGATCTCTACCGCCAATTCCCCGTGTTCGCCCACGCCCTCGACGAG
GTCGCTGCGGCGCTGAACCCGCATCTCGATGTTGCGTTGCTTGAGGTGATGTTCAGCCAA
CAAGACACTGCCATGGCGCAACTGCTGGACCAGACCTTCTATGCACAACCGGCGTTGTTC
GCGCTGGGAACCGCTCTACATCGATTGTTCACCCACGCCGGTATCCACCCGGACTACCTG
CTAGGCCACTCCATCGGAGAACTCACCGCGGCATACGCCGCCGGTGTGCTGTCACTGCAA
GACGCAGCCACCTTGGTCACAAGCCGAGGACGACTGATGCAATCCTGCACGCCCGGCGGG
ACGATGCTCGCACTACAAGCCAGCGAAGCAGAAGTACAACCGCTGCTTGAAGGCCTAGAC
CACGCCGTGTCCATCGCCGCGATCAACGGAGCAACGTCGATCGTACTGTCAGGAGATCAC
GACAGCCTCGAACAAATCGGCGAGCACTTCATTACCCAAGATCGACGTACCACCCGACTG
CAGGTCAGTCACGCTTTCCACTCTCCACATATGGACCCCATCCTCGAACAATTCCGCCAG
ATCGCGGCCCAACTCACCTTCAGCGCACCCACCCTGCCCATCTTGTCCAACCTCACCGGG
CAGATCGCCCGCCACGACCAACTCGCCTCACCTGACTATTGGACCCAACAGCTACGTAAC
ACTGTCCGGTTCCATGACACTGTCGCTGCCCTGCTCGGGGCGGGTGAGCAGGTTTTCCTG
GAACTTTCACCTCACCCGGTGTTGACACAAGCGATCACCGACACCGTCGAACAAGCCGGC
GGCGGCGGCGCAGCAGTGCCAGCTCTACGCAAGGATCGCCCTGATGCTGTCGCGTTCGCT
GCAGCACTCGGCCAGCTGCACTGCCATGGCATCAGCCCATCCTGGAATGTTCTTTACTGC
CAGGCCCGCCCCCTCACACTGCCCACCTACGCTTTCCAGCATCAGCGTTACTGGCTGCTG
CCCACCGCTGGTGATTTCAGCGGGGCCAATACCCACGCCATGCATCCGCTGCTAGACACC
GCCACCGAACTGGCCGAAAACCGCGGATGGGTGTTCACCGGCCGGATCAGCCCACGCACC
CAACCATGGCTAAACGAACACGCCGTCGAATCAGCCGTGCTGTTCCCAGGCACCGGATTT
GTCGAGCTAGCGCTGCATGTCGCTGACCGTGCCGGATATTCCTCGGTCAACGAACTGATC
GTGCACACCCCCCTGCTACTCGCTGGCCACGACACCGCGGATCTACAGATCACCGTCACC
GACACCGATGACATGGGCCGGCAGTCTCTTAACATCCACTCGCACCCACATATCGGCCAT
GACAACACCACCACCGGCGATGAACAACCCGAGTGGGTCCTGCATGCCAGCGCAGTCCTG
ACCGCACAAACCACCGACCACAACCACCTCCCCCTAACGCCTGTGCCGTGGCCTCCACCC
GGCACAGCCGCGATCGAGGTGGATGACTTCTACGACGACCTGGCTGCACAGGGCTACAAC
TACGGCCCGACATTCCAAGGTGTGCAACGGATATGGCGTGACCACGCCACACCCGATGTC
ATCTACGCCGAAGTTGAACTACCCGAAGACACCGACATCGACGGCTACGGCATCCACCCC
GCCCTATTCGACGCCGCTTTACACCCCCTACTCGCCCTGACCCAACCCCCCACCAACGAC
ACCGATGACACCAACACCGCAGACACCGGTGACCAGGTGCGGCTGCCCTACGCCTTTACC
GGCATCAGTTTGCACGCCACCCACGCCACCCGATTGCGGGTACGGCTGACCCGTACCGGC
GCCGATGCCATCACCGTGCACACCAGTGACACCACCGGAGCCCCGGTGGCGATCATCGAC
TCATTGATCACCCGCCCCCTCACCACCGCCACAGGGTCTGCTCCGGCAACCACAGCAGCT
GGCCTACTACACCTGAGCTGGCCACCACACCCTGACACCACGACCGACACCGACACCGAC
ACCGATGCCCTGCGGTATCAGGTGATCGCCGAACCCACTCAACAACTGCCCCGCTACCTG
CACGACCTACACACCAGCACCGACCTGCACACCAGCACCACCGAAGCAGACGTGGTTGTG
TGGCCGGTACCGGTGCCCAGCAACGAAGAGCTCCAGGCACACCAAGCATCCGACACCGCG
GTGTCTTCTCGGATACACACCCTGACCCGCCAAACACTTACCGTGGTGCAGGACTGGCTC
ACTCACCCCGACACCACCGGCACCCGACTGGTCATCGTGACCCGCCACGGCGTCAGCACC
AGTGCCCACGACCCGGTCCCCGACCTAGCCCACGCCGCAGTGTGGGGCCTGATCCGCAGC
GCCCAAAACGAACACCCCGGACGCTTCACACTGCTCGACACCGACGACAACACCAACAGC
GACACCCTCACCACCGCCCTAACCCTGCCAACCCGCGAAAACCAACTGGCCATACGCCGC
GACACCATCCACATCCCCCGCCTGACCCGCACCGCTGTCCTGACACCACCGGACAGCGGC
CCCTGGCGCCTTGACACCACCGGCAAGGGTGATCTGGCCAACCTCGCCCTGCTACCGACC
GCCCACACTGCCCTGGCCTCTGGACAAATCCGTATCGATGTCCGGGCCGCTGGTTTGAAT
TTTCACGACGTGGTCGTCGCGTTGGGGCTAATCCCCGACGACGGATTCGGCGGAGAAGCC
GCCGGGGTGATCAGCGAGATCGGTCCCGACGTCTACGGATTCGCCGTGGGTGATGCCGTG
ACCGGCATGACCGTCTCTGGTGCGTTTGCCCCCAGCACTGTCGCTGATCACCGCATGGTG
ATGACGATCCCGGCCCGGTGGTCCTTCCCCCAAGCCGCATCCATACCGGTGGTATTCCTG
ACCGCCTACATCGCTTTGGCCGAGATCTCGGGCCTAAGCCGAGGGCAACGAGTGCTGATC
CATGCCGGCACTGGCGGTGTGGGTATGGCTGCGATTCAATTGGCACACCATTTGGGTGCC
GAAGTATTCGCCACCGCCAGCGCCGCGAAATGGAGCACCCTTGAGGCACTGGGGGTACCG
CGCGACCATATCGCTTCCTCGCGTACTCTGGACTTTTCCAACGCATTCCTCGATGCCACC
AACGGCGCCGGTGTTGATGTCGTATTGAACTGCCTCAGTGGTGAATTCGTCGAAGCATCC
CTAGCCCTGCTGCCCCGCGGTGGCCATTTCGTCGAAATCGGCAAAACCGACATCCGTGAT
ACCGAGGTCATCGCCGCAACCCATCCCGGCGTCATTTACCGCGCCCTCGATCTGCTCAGC
GTCTCCCCCGATCACATCCAGCGCACACTGGCCCAACTGTCCCCACTGTTTGCCACCGAC
ACCCTAAAACCCCTACCGACCACTAATTACAGCATCTACCAAGCCATCTCGGCCTTACGT
GACATGAGTCAAGCCCGTCACACAGGCAAGATCGTGCTCACTGCGCCGGTGGTGGTAGAT
CCTGAGGGCACGGTGTTGATCACCGGGGGGACCGGGACGCTGGGTGCCTTGTTCGCCGAG
CATCTGGTTTCTGCCCATGGTGTCCGGCATCTGTTGTTGACCTCGCGGCGCGGACCTCAG
GCCCACGGTGCCACCGATCTGCAGCAGCGGCTCACCGATCTAGGTGCTCATGTCACCATC
ACGGCCTGCGATATCAGCGACCCCGAAGCACTGGCCGCCCTGGTCAATTCAGTGCCCACA
CAACACCGTTTAACCGCGGTAGTGCACACCGCCGCGGTATTGGCCGACACCCCGGTCACC
GAGTTGACCGGCGATCAACTCGACCAGGTGCTGGCCCCCAAAATCGACGCGGCATGGCAG
CTGCACCAACTCACCTACGAACACAACCTGTCTGCATTCATCATGTTCTCGTCCATGGCC
GGAATGATAGGCAGTCCCGGTCAGGGTAACTACGCGGCAGCCAACACCGCGTTAGATGCT
CTCGCCGACTACCGCCACCGCCTGGGCTTGCCCGCGACCAGCCTGGCCTGGGGCTACTGG
CAGACCCGCACCGGTGTCACCGCGCATCTAACCGATGTAGATCTAGCCCGCATGACCCGC
CTGGGTTTGATGCCCATCGCCACCAGCCACGGACTGGCCCTGTTCGATGCCGCCCTCGCC
ACCGGACAGCCCGTTTCGATACCCGCCCCGATCAACACCCACACCCTGGCCCGACACGCC
CGCGACAACACCCTGACCCCGATCCTGTCTGCGCTGATCACCACACCACGGCGCCGGGCG
GCCTCTGCCGCAACCGATCTCGCTGCCCGCCTCAACGGACTTAGCCCCCAACAGCAACAA
CAAACACTGGCCACCCTCGTGGCCGCGGCCACCGCCACCGTGCTGGGCCACCACACCCCC
GAAAGCATCAGCCCAGCCACCGCGTTCAAAGACCTCGGAATCGATTCGCTGACCGCCCTT
GAACTGCGCAACACCCTCACCCACAACACCGGCCTGGATCTGCCCCCCACCCTCATCTTC
GATCACCCCACACCCCATGCGCTAACCCAACACCTGCACACCCGACTCACCCAAAGCCAT
ACCCCGGTCGGACCAATTGCGTCCCTGCTAAGCCACGCGATCGATGAGGGCAAATTCCGT
GCCGGCGCTGACCTATTGATGGCCGCATCCAATTTGAACCAAAGTTTCAGCAATATGGCT
GAACTCAACCAGCTCCCGGCCGTGACGGACATAGCTGACGCGTCTCCTGATGGGCTACTC
ACCCTGATCTGCATCTCTACCTCAGAGAATGAGTACGCTCGCCTCGCTGCTGCGAACATT
CATTCACTGACCTTCGCTGAAATTGCGGCGCCCGGCTTTTACGACGCGCAGCTGCCAAAT
TCGATAGAGACGTCGGCAGAGGCGCTGGCAACTGCCATCACAGGCGCCTACGCAAATACG
TCCATTGTTCTGGTAGCGCACTCCATTGTCTGCGAGCTAGCTCAGGCAACGATGACACGT
CTACAAGACGCTGACATCGATCTTGTGGGTCTGGTTCTGTTGGATCCACTCGAAGGGACT
AACAGCACTGAAGATTATGTGGAGACAGTCTTGACTCGAATCGAGCATATCAATGCACCG
AGGGTCGGAGTAGACGGTTACCTTGCCGCCCTGGGCCGCTATCTCCAATTCCACGAAGAC
CGCCGAATACCAATACCGGAAACGCGGCACATGACACTGCACTCGGACACGAAAATTGAC
CGTGCCCAAACACCAATGAACTTATTACAAGATGAGGCAGCGTTGACCGCCCTCAAAATA
GGAAACTGGATGAACGACACAGGGAGTATCGCAGTAACACTGAGAGATGGACCCGTATTC
TTGGGCAGGGCCCGCTCTGTCAACATGAGGTGA
[9] KS35..408
[9] AT590..912
[9] malonyl-CoA784..788
[9] DH955..1128
[9] ER1470..1773
[9] KR1783..1963
[9] ACP2063..2133
[9] KS103..1224
[9] AT1768..2736
[9] malonyl-CoA2350..2364
[9] DH2863..3384
[9] ER4408..5319
[9] KR5347..5889
[9] ACP6187..6399

close this sectionFeature

BLASTP
Database:UniProtKB:2010_04 		show BLAST table
InterPro
Database:interpro:26.0
IPR001227 Acyl transferase domain (Domain)
[587-878] 6.80004680300071e-73 G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR006162 Phosphopantetheine attachment site (PTM)
[2091-2106] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR006163 Phosphopantetheine-binding (Domain)
[2067-2132] 5.8e-10 PF00550
PF00550   PP-binding
IPR009081 Acyl carrier protein-like (Domain)
[2063-2133] PS50075
PS50075   ACP_DOMAIN
[2055-2147] 1.9e-21 SSF47336
SSF47336   ACP_like
IPR011032 GroES-like (Domain)
[1466-1598] 1.2e-26 SSF50129
SSF50129   GroES_like
IPR013149 Alcohol dehydrogenase, zinc-binding (Domain)
[1606-1713] 1.5e-16 PF00107
PF00107   ADH_zinc_N
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
[1488-1543] 0.028 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
[1783-1961] 5.00000000000001e-59 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[35-282] 2.99999999999998e-92 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[290-408] 1.40000000000001e-41 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[590-912] 1.9e-70 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
[3-27] 1.2e-05 PF08990
PF08990   Docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[588-880] 1.8e-76 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[718-783] 3.1e-15 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[27-286] 1.79999754022378e-78 G3DSA:3.40.47.10 [296-457] 1.2000011745814e-46 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[27-287] 6.1e-79 SSF53901 [249-464] 8e-77 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1571-1748] 2.4e-41 SSF51735 [1776-2052] 6.5e-47 SSF51735
SSF51735   NAD(P)-bd
[1557-1750] 1.99999636034536e-45 G3DSA:3.40.50.720 [1784-1943] 2.30000440726539e-30 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[195-211] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[592-893] 1.59998835313644e-116 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding (Domain)
[2064-2136] 6.09999977126211e-28 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[955-1128] 8.6000633021393e-67 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase region (Region)
[37-460] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1783-1963] 8.79996401030972e-53 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
[1470-1773] SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit
MUP_00380 MUP_00380   MUP_00400 MUP_00400
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