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CDS information : Madu_00400


close this sectionLocation

Organism
StrainATCC 39144
Entry nameMaduropeptin
Contig
Start / Stop / Direction60,834 / 61,589 / + [in whole cluster]
60,834 / 61,589 / + [in contig]
Location60834..61589 [in whole cluster]
60834..61589 [in contig]
TypeCDS
Length756 bp (251 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative AraC family transcriptional regulator
Product (GenBank)transcription regulatory protein
Gene
Gene (GenBank)mdpR2
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[17918933] Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis. (J Am Chem Soc. , 2007)
Related Reference
ACC
Q8GME4
NITE
C1027_00490
PmId
[19159491] Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027. (BMC Microbiol. , 2009)
[20551990] Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027. (J Antibiot (Tokyo). , 2010)

close this sectionSequence

selected fasta
>putative AraC family transcriptional regulator [transcription regulatory protein]
MDARTTDSIKRVIETIHHNIGEKITIDDMARTAMFSKFHFTRLFQRATGVSPGRFLSAVR
LQEAKRLLLTTELSVTEISHRVGYTSVGTFSSRFKSSVGLSPSAYRELTGYAPHITDAPP
AKGRNASVVHGEIVPPPSDDETGPVFLGLFPDTIPQGNPVRCTVLPRPGRFKLENVPDGC
WYLLAQSVRPGYEEVLGDLPPIVGAHGPITMHGEPVVRLVEVRLRPMQTLDPPVLLALLD
ARRTALHAAAG
selected fasta
>putative AraC family transcriptional regulator [transcription regulatory protein]
ATGGACGCGCGCACGACGGACAGCATTAAGCGGGTCATCGAAACCATTCATCACAATATC
GGGGAGAAGATCACGATCGACGACATGGCCCGCACCGCGATGTTCAGTAAATTCCACTTT
ACCCGACTCTTCCAGCGAGCGACCGGCGTCTCACCAGGAAGATTCCTCTCCGCAGTCCGC
CTGCAGGAGGCGAAACGGCTGCTGCTCACCACGGAACTCAGCGTCACCGAGATCAGCCAC
CGCGTCGGATACACCAGCGTCGGCACCTTCAGTTCCCGTTTCAAGAGCAGCGTGGGCCTT
TCGCCCAGCGCCTATCGCGAGTTGACGGGCTACGCGCCGCACATCACCGACGCGCCCCCG
GCAAAAGGGCGCAACGCCAGCGTGGTGCACGGGGAGATAGTGCCGCCGCCGTCGGACGAC
GAAACCGGCCCGGTCTTTCTGGGGCTGTTTCCCGACACCATCCCGCAGGGGAATCCGGTC
CGCTGCACGGTGCTCCCCCGGCCGGGCCGCTTCAAGCTGGAGAACGTTCCCGACGGCTGC
TGGTACCTGCTCGCCCAGTCGGTCCGGCCGGGCTACGAGGAGGTCCTCGGCGACCTGCCC
CCGATCGTCGGAGCGCACGGGCCCATCACGATGCACGGGGAACCGGTCGTCCGGCTGGTG
GAGGTGCGGCTGCGGCCGATGCAGACGCTGGATCCCCCCGTGCTGCTCGCCCTGCTCGAC
GCGCGGCGCACGGCGCTGCACGCCGCGGCGGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR009057 Homeodomain-like (Domain)
 [5-59]  8.49999999999995e-26 G3DSA:1.10.10.60 [60-107]  1.3e-21 G3DSA:1.10.10.60
G3DSA:1.10.10.60   Homeodomain-rel
 [5-56]  5.29999657550189e-11 SSF46689 [59-107]  8.29999581180007e-14 SSF46689
SSF46689   Homeodomain_like
IPR018060 DNA binding HTH domain, AraC-type (Domain)
 [10-108]  PS01124
PS01124   HTH_ARAC_FAMILY_2
 [23-106]  7.90003079443025e-34 SM00342
SM00342   HTH_ARAC
IPR018062 HTH domain AraC-type, conserved site (Conserved_site)
 [60-102]  PS00041
PS00041   HTH_ARAC_FAMILY_1
IPR020449 Transcription regulator HTH, AraC- type (Family)
 [75-90]  2.19999900980708e-06 PR00032 [90-106]  2.19999900980708e-06 PR00032
PR00032   HTHARAC
SignalP No significant hit
TMHMM No significant hit