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Medem_00080 Medem_00080   Medem_00100 Medem_00100

CDS information : Medem_00090


close this sectionLocation

Organism
StrainAM-7161
Entry nameMedermycin
Contig
Start / Stop / Direction8,973 / 7,948 / - [in whole cluster]
8,973 / 7,948 / - [in contig]
Locationcomplement(7948..8973) [in whole cluster]
complement(7948..8973) [in contig]
TypeCDS
Length1,026 bp (341 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative oxidoreductase
Product (GenBank)enoyl reductase
Gene
Gene (GenBank)med-ORF29
EC number
Keyword
Note
Note (GenBank)
  • GTG start codon
Reference
ACC
PmId
[12855716] Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters. (Microbiology. , 2003)
Related Reference
ACC
Q59I44
PmId
[15781461] 2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds. (J Biol Chem. , 2005)
ACC
Q53927
NITE
Actino_00040
PmId
[7929165] DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2). (J Biol Chem. , 1994)
[10805574] Chemical characterisation of disruptants of the Streptomyces coelicolor A3(2) actVI genes involved in actinorhodin biosynthesis. (J Antibiot (Tokyo). , 2000)

close this sectionSequence

selected fasta
>putative oxidoreductase [enoyl reductase]
MLSVVMEEFGGPEVLRARQVEDPEPGPGQVLVDVAYASVTFVETQVRSGNGPFGRPALPR
VPGNGVGGRVVALGPGADPALLGTVVVTTTGGEGGYAERALARADEVVPVPPGLALKDAV
ALLADGRTALLLFRQAEVKPGEKVLVEAAAGGVGSLLVQLAVHAGARVVGAARGDRKAEL
VVSLGASYVDYSREAWLRQVRETAGGGDLDVVFDGVGGAIGTAAAGALRPGGRISLYGMA
SGADATLDEDDLAARGIRTLGLFAAPGPAETHPLIGEALRLAADGVLAPVVGQVFPLAAA
AEAHAAIEARATVGKTLLAVGAQEGDTYGTGAAGGATNGDR
selected fasta
>putative oxidoreductase [enoyl reductase]
GTGCTGTCCGTGGTGATGGAGGAGTTCGGAGGACCGGAGGTCCTGCGGGCTCGACAGGTG
GAGGATCCGGAGCCCGGCCCCGGCCAGGTGCTGGTCGACGTGGCGTACGCGAGCGTCACC
TTCGTCGAGACCCAGGTGCGCTCCGGCAACGGCCCCTTCGGCCGCCCCGCGCTCCCCCGG
GTGCCGGGCAACGGTGTGGGCGGCCGCGTCGTCGCCCTCGGCCCGGGTGCGGACCCCGCC
CTGCTCGGCACGGTCGTGGTCACCACGACCGGCGGCGAGGGCGGCTACGCCGAACGCGCC
CTGGCCCGGGCCGACGAGGTCGTCCCGGTCCCGCCCGGCCTCGCCCTCAAGGACGCGGTC
GCCCTGCTCGCCGACGGCCGCACCGCTCTCCTGCTCTTCCGTCAGGCGGAGGTCAAGCCG
GGCGAGAAGGTCCTCGTGGAGGCCGCGGCCGGCGGTGTCGGCAGCCTCCTGGTCCAGCTG
GCCGTGCACGCCGGCGCCCGCGTGGTCGGTGCCGCGCGCGGCGACCGGAAGGCCGAGCTG
GTCGTCTCCCTCGGCGCCTCCTACGTCGACTACTCGCGGGAGGCGTGGCTCCGCCAGGTC
CGGGAGACGGCCGGCGGCGGCGACCTCGACGTCGTCTTCGACGGGGTGGGCGGCGCCATC
GGCACCGCGGCGGCGGGCGCGCTGCGCCCCGGAGGGCGCATCAGCCTGTACGGCATGGCG
AGCGGCGCGGACGCCACGCTCGACGAGGACGACCTCGCCGCCCGGGGCATCCGCACCCTC
GGGCTCTTCGCCGCGCCGGGCCCCGCCGAGACCCACCCCCTCATCGGAGAGGCCCTGCGG
CTCGCGGCGGACGGCGTCCTCGCGCCGGTCGTCGGCCAGGTCTTCCCGCTCGCCGCGGCG
GCCGAGGCGCACGCGGCCATCGAGGCGCGGGCCACCGTGGGGAAGACCCTGCTCGCCGTC
GGCGCCCAGGAGGGCGACACGTACGGCACCGGCGCCGCCGGCGGCGCGACGAACGGCGAC
CGATGA

close this sectionFeature

BLASTP
Database:UniProtKB:2010_04 		show BLAST table
InterPro
Database:interpro:26.0
IPR011032 GroES-like (Domain)
[1-144] 4e-30 SSF50129
SSF50129   GroES_like
IPR013149 Alcohol dehydrogenase, zinc-binding (Domain)
[152-274] 3.3e-21 PF00107
PF00107   ADH_zinc_N
IPR016040 NAD(P)-binding domain (Domain)
[104-295] 2.60000517657743e-39 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
[113-285] 8.9e-36 SSF51735
SSF51735   NAD(P)-bd
SignalP
[1-17] 0.093 Signal
Eukaryota   
TMHMM No significant hit
Medem_00080 Medem_00080   Medem_00100 Medem_00100
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