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CDS information : Mith_00130


close this sectionLocation

Organism
StrainATCC 12956
Entry nameMithramycin
Contig
Start / Stop / Direction16,025 / 16,477 / + [in whole cluster]
16,025 / 16,477 / + [in contig]
Location16025..16477 [in whole cluster]
16025..16477 [in contig]
TypeCDS
Length453 bp (150 aa)
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close this sectionAnnotation

Category5.4 hypothetical protein
Producthypothetical protein
Product (GenBank)cyclase
Gene
Gene (GenBank)mtmX
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[8654997] Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin. (Gene. , 1996)
Related Reference
ACC
Q2PA04
NITE
Stref_00110
PmId
[16751529] Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin. (Appl Environ Microbiol. , 2006)
ACC
Q9ZAT9
NITE
Adria_00050
PmId
[9864344] Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene. (J Bacteriol. , 1999)
[10631513] A two-plasmid system for the glycosylation of polyketide antibiotics: bioconversion of epsilon-rhodomycinone to rhodomycin D. (Chem Biol. , 1999)
ACC
Q53925
NITE
Actino_00020
PmId
[17227452] Possible involvement of ActVI-ORFA in transcriptional regulation of actVI tailoring-step genes for actinorhodin biosynthesis. (FEMS Microbiol Lett. , 2007)

close this sectionSequence

selected fasta
>hypothetical protein [cyclase]
MTAPTETQPHSSAGFGSLYAEIQQFYARHMQLLDGGAADEWAADFTEDASFSVPTVPAPV
VGRDALAAAVRRTAESLASTGEQHRHWPGVFDVRPRRDGSVVVHSYTTVYASPRGGESRV
HRVCTCTDVLVREDGRLLVRSREVIRDDLR
selected fasta
>hypothetical protein [cyclase]
GTGACCGCGCCGACCGAGACACAGCCGCACTCCTCCGCCGGGTTCGGCTCCCTGTACGCG
GAGATCCAGCAGTTCTACGCCCGCCACATGCAGCTCCTCGACGGGGGAGCCGCCGACGAG
TGGGCGGCCGACTTCACCGAGGACGCGTCGTTCTCGGTGCCGACCGTGCCGGCACCGGTG
GTGGGCCGGGACGCCCTGGCAGCCGCGGTGCGGCGCACCGCCGAGTCCCTGGCCTCCACT
GGTGAGCAGCACCGCCACTGGCCCGGCGTCTTCGACGTCCGGCCGCGGCGGGACGGCTCC
GTGGTGGTCCACTCGTACACCACCGTGTACGCCTCACCGCGTGGCGGGGAGTCCCGCGTG
CACCGCGTCTGCACCTGCACGGACGTCCTGGTCCGCGAGGATGGCCGGCTGCTCGTGCGG
TCCCGCGAGGTCATCCGTGACGACCTGCGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
No significant hit
SignalP No significant hit
TMHMM No significant hit