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CDS information : Nanch_00150

Location

Organism	Streptomyces nanchangensis
Strain	NS3226
Entry name	Nanchangmycin
Contig	AF521085
Start / Stop / Direction	66,881 / 67,798 / + [in whole cluster] 66,881 / 67,798 / + [in contig]
Location	66881..67798 [in whole cluster] 66881..67798 [in contig]
Type	CDS
Length	918 bp (305 aa)

Annotation

Category	2.3 modification addition of sugar moiety
Product	putative NDP-hexose O-methyltransferase
Product (GenBank)	NanM
Gene
Gene (GenBank)	nanM
EC number	2.1.1.-
Keyword	4-O-methyl-L-rhodinose
Note
Note (GenBank)	putative methyltransferase
Reference	ACC Q7WTE8 PmId [12770825] A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. (Chem Biol. , 2003)
Related Reference	ACC Q2I754 PmId [16632249] Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tu6071: analysis of the gene cluster and generation of derivatives. (Chem Biol. , 2006)

Sequence

>putative NDP-hexose O-methyltransferase [NanM]
MAQGFQASLQWERINELWVTEEASADLTGFKSDRRNFNIALWDPTTNGIRYLRALVYELA
TRLSDDDWSKIEKVRNRDVGDPVTVRYEGRTVCLDYLQAALELGFIEKELDLGGARVLEI
GAGYGRTCHAMLSNYDLASYTIVDLKNTLGLSRAYLREVLDEKQFSKMRFVQVEDIDTGL
GPDGFDLCVNVHSFTEMTPDTVKAYLRLIDERCGAFFVKNPVGKFRDKSMDGHQKGEEAV
RLAMQTGPLRQVLDIHDSQAVAAAVPAFIEAYQPGEGWTCAANTRGMPWSYFWQALYTKT
GDDLR

>putative NDP-hexose O-methyltransferase [NanM]
ATGGCTCAGGGTTTTCAGGCCAGCCTGCAGTGGGAACGCATCAATGAACTCTGGGTTACC
GAGGAGGCGTCGGCTGATCTGACCGGCTTCAAGTCGGACCGCCGGAATTTCAATATCGCC
CTGTGGGATCCGACGACCAACGGAATCAGGTATCTGAGGGCTCTCGTCTACGAGTTGGCC
ACGCGGCTGAGCGACGACGACTGGTCGAAGATCGAGAAAGTCCGCAACCGTGACGTGGGA
GATCCGGTCACCGTCCGATACGAGGGCAGGACCGTCTGTCTGGACTATCTCCAGGCGGCG
CTCGAGCTCGGCTTCATCGAGAAGGAACTGGACCTGGGCGGCGCCCGCGTCCTGGAGATC
GGCGCCGGGTACGGCCGTACGTGCCATGCGATGCTCTCCAACTACGACCTGGCCTCCTAC
ACCATCGTCGACCTGAAGAACACCCTCGGGCTGAGCAGGGCGTATCTTCGCGAGGTCCTG
GACGAGAAGCAGTTCTCCAAGATGAGGTTCGTCCAGGTGGAGGACATCGACACGGGGCTG
GGCCCGGACGGCTTCGACCTGTGCGTCAACGTGCACTCCTTCACGGAGATGACCCCGGAC
ACCGTCAAGGCGTATCTGCGCCTGATCGACGAGAGGTGCGGGGCGTTCTTCGTGAAGAAC
CCGGTCGGAAAGTTCCGGGACAAGAGCATGGACGGCCACCAGAAGGGCGAGGAGGCCGTG
CGGCTGGCCATGCAGACCGGGCCGCTGCGGCAGGTGCTCGACATCCATGACAGCCAGGCC
GTGGCGGCCGCCGTGCCGGCCTTCATCGAGGCCTATCAGCCCGGCGAGGGATGGACGTGC
GCCGCCAACACCCGCGGCATGCCCTGGAGTTACTTCTGGCAGGCCCTCTACACGAAGACC
GGCGACGACCTTCGATAG

Feature

BLASTP Database:UniProtKB:2010_04	show BLAST table
InterPro Database:interpro:26.0	IPR003333 Cyclopropane-fatty-acyl-phospholipid synthase (Family) PF02353 CMAS
SignalP	Eukaryota
TMHMM	No significant hit

Nanch_00140 Nanch_00160

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