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CDS information : Nysta_00190


close this sectionLocation

Organism
StrainATCC 11455 (=NBRC 15452)
Entry nameNystatin
Contig
Start / Stop / Direction117,033 / 119,816 / + [in whole cluster]
117,033 / 119,816 / + [in contig]
Location117033..119816 [in whole cluster]
117033..119816 [in contig]
TypeCDS
Length2,784 bp (927 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
ProductLuxR family transcriptional regulator
Product (GenBank)NysRIII
Gene
Gene (GenBank)nysRIII
EC number
Keyword
Note
Note (GenBank)
  • transcriptional regulator
Reference
ACC
PmId
[10873841] Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway. (Chem Biol. , 2000)
[14973031] In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. (J Bacteriol. , 2004)

close this sectionSequence

selected fasta
>LuxR family transcriptional regulator [NysRIII]
MLLERENELARIRAALDAAEAGDSSLLLINGPLGSGRSALLRRIPELAGDGTRVLRASAA
WRERDFPFGIARQLFDHLLSGAGGAGPAERTAGAEHFSRLMDTGDRPTGTGPALEVSQAV
LQGAQALLADASAERRLLILVDDLQWADGPSLRWLAHLTRRLHGLRALLVCTLADGDHRG
RYPLVREVAGAAHTVLRLAPLSRDATRVLLAGPQGRPPQDALVRAVYEASRGNPLFLTAF
RSALRATGRPPGGDHFGAVRELSPTVLRDRLAGHLRIQPQPVREVAVAVAALGDHSDPVL
LAQLAGVDEIGFAGARRALVDAGLLARGRDVRFVHGVVRDAVDSLLTLDERERSHDDAAD
LLYRCGRPAEQVAGHLLAVVHPGRPWSEAVLRSAAHNALRAGRPADAARYLRRALLHHRT
QDGCRARILVDLATAERALDPDACVRHVSQAVALLDTSRDRAAAVLRIPPSLLAAPSPSA
VELVRQAAAGLDEPGQRDEEGADELALRLEAWLRHSGHENPVELASSVARLRRMGARPPV
DSVAERELVAVLLSAGALSGRLSAAEIADTGNRILEREPATAAHAHTPLPLVMLSLFVAE
SVQGVASWLASEQHTRRRYATGADDVLLTAERAFVLVTQGRPAAAREHVERALVMDAGDW
SEPAVMMFAAVAFELRDPALSERILERIRDRRPAGLALTATGQMLQAAVDVHFGRGRDAL
DTLLACGRRLETVGWRNSALLPWRPYAIGLHQRLGETDAALQLAEDELRWAREWGATTNL
GRALRLKGWLLQDEGLDLLRESVEILRASSYATELARTLVVLGRRLPGGPEAEAVLREAA
GIAAACGVPWLAERAELGLGSAIVPPVATLTPSERRVASLVSRGLTNQAIATELGVSSRA
VEKHLTSAYRKLGVSGRRELVNALPGR
selected fasta
>LuxR family transcriptional regulator [NysRIII]
ATGCTTCTTGAGCGGGAGAACGAACTGGCCCGGATCCGGGCCGCCCTGGACGCCGCGGAA
GCGGGCGACTCCTCGCTCCTCCTGATCAACGGTCCCCTCGGCAGCGGGCGTTCGGCGCTG
CTGCGCCGGATACCGGAGCTGGCCGGCGACGGCACCCGCGTCCTGCGGGCCAGCGCCGCC
TGGCGGGAACGCGACTTCCCCTTCGGGATCGCCCGCCAACTCTTCGACCACCTGCTGTCC
GGGGCGGGCGGCGCAGGGCCGGCCGAACGCACCGCCGGGGCAGAGCACTTCAGCCGACTG
ATGGACACCGGCGACCGCCCTACCGGGACCGGCCCCGCCCTGGAGGTCTCCCAGGCAGTG
CTCCAGGGCGCCCAGGCGCTGCTCGCCGACGCGTCCGCGGAGCGGCGCCTGCTGATCCTG
GTCGACGACCTCCAGTGGGCCGACGGCCCGTCCCTGCGCTGGCTGGCCCACCTCACCCGG
CGGCTGCACGGCCTGCGGGCGCTGCTGGTGTGCACGCTGGCCGACGGCGACCACCGGGGC
AGGTACCCCCTGGTCCGGGAGGTCGCCGGCGCCGCGCACACCGTCCTGCGCCTGGCGCCG
CTGTCCCGGGACGCCACCCGCGTCCTGCTCGCCGGGCCCCAGGGCCGGCCGCCGCAGGAC
GCACTGGTGCGCGCCGTGTACGAGGCGTCCAGGGGCAACCCGCTGTTCCTGACCGCCTTC
CGGAGCGCTCTGCGCGCCACCGGAAGGCCGCCCGGCGGCGACCACTTCGGCGCCGTCCGG
GAGCTGAGCCCGACGGTGCTGCGCGATCGGCTCGCGGGCCATCTGCGGATCCAGCCGCAG
CCGGTGCGCGAGGTCGCGGTGGCGGTGGCCGCGCTGGGCGACCACAGCGATCCGGTGCTG
CTCGCCCAGCTCGCCGGGGTCGATGAAATCGGTTTCGCCGGTGCCCGCCGCGCGCTGGTG
GACGCCGGCCTGTTGGCCCGGGGACGGGACGTCCGCTTCGTCCACGGCGTCGTCCGCGAT
GCGGTGGACTCCCTGCTCACCCTCGACGAGCGGGAACGCTCGCACGACGACGCCGCCGAT
CTGCTGTACCGCTGCGGGCGGCCGGCCGAGCAGGTCGCCGGCCATCTGCTGGCCGTGGTC
CACCCGGGCCGGCCCTGGTCGGAGGCGGTCCTGCGCTCCGCGGCCCACAACGCGCTGCGC
GCCGGCCGGCCCGCCGACGCGGCCCGGTACCTGCGCCGCGCCCTGCTGCACCACCGCACC
CAGGACGGCTGCCGCGCCCGCATCCTGGTCGATCTGGCCACCGCCGAGCGCGCCCTCGAC
CCCGATGCCTGTGTACGCCACGTCAGCCAGGCGGTCGCGCTGCTGGACACCTCGCGGGAT
CGGGCCGCCGCCGTGTTGCGCATCCCGCCGTCCCTGCTCGCCGCCCCCAGCCCGTCCGCC
GTCGAGTTGGTGCGGCAGGCCGCCGCCGGGCTCGACGAACCGGGGCAGCGGGACGAGGAG
GGAGCCGACGAACTCGCCCTGCGCCTGGAGGCGTGGCTGCGGCACTCCGGCCACGAGAAC
CCCGTCGAGCTGGCGTCCTCGGTGGCGCGGCTGCGGCGCATGGGGGCACGGCCGCCGGTG
GACAGCGTCGCCGAACGCGAGTTGGTCGCCGTGCTGTTGAGTGCGGGCGCGCTCAGCGGC
CGGCTCAGCGCCGCGGAGATCGCCGACACCGGCAACCGCATCCTCGAACGTGAGCCGGCC
ACCGCCGCCCATGCCCACACCCCGCTGCCGCTGGTGATGCTCTCGCTGTTCGTCGCCGAG
TCCGTGCAGGGCGTGGCCTCCTGGCTGGCCAGCGAACAGCACACCCGGCGCCGGTACGCG
ACCGGCGCGGACGATGTGCTGCTGACCGCCGAGCGGGCCTTCGTCCTGGTGACGCAGGGC
CGCCCGGCCGCCGCGCGGGAGCACGTCGAACGCGCCCTGGTCATGGACGCCGGCGACTGG
TCGGAACCCGCCGTCATGATGTTCGCCGCGGTCGCCTTCGAACTGCGCGACCCGGCCTTG
AGCGAACGCATCCTGGAACGGATCCGCGACCGCCGGCCGGCCGGACTGGCGCTCACCGCC
ACCGGTCAGATGCTCCAGGCCGCCGTCGACGTGCACTTCGGCCGGGGGCGGGACGCCCTG
GACACGCTGCTGGCCTGTGGCCGACGCCTGGAGACCGTGGGATGGCGCAATTCCGCACTG
CTGCCCTGGCGTCCGTATGCAATCGGGCTGCACCAGCGGCTCGGCGAGACCGATGCCGCG
CTGCAACTCGCCGAGGACGAGCTGAGGTGGGCCCGGGAGTGGGGTGCGACGACGAACCTG
GGCCGGGCCCTGCGCCTGAAGGGCTGGCTGTTGCAGGACGAGGGACTGGATCTGCTGCGT
GAGAGCGTCGAGATCCTCCGCGCTTCGTCCTACGCGACGGAACTGGCGCGCACCCTCGTC
GTCCTCGGGCGTCGGCTGCCGGGTGGGCCGGAGGCCGAGGCGGTGTTGCGGGAGGCCGCG
GGGATCGCCGCCGCCTGTGGTGTTCCCTGGCTCGCCGAACGGGCCGAACTCGGTCTGGGC
AGTGCCATCGTGCCGCCGGTCGCCACCCTGACCCCCAGCGAGCGGCGAGTGGCGTCGCTG
GTGAGCCGGGGCCTGACCAACCAGGCCATCGCGACCGAACTCGGTGTGAGCTCCCGGGCG
GTGGAGAAGCACCTCACCAGCGCCTATCGCAAGCTCGGCGTCTCCGGCCGCCGCGAGTTG
GTGAATGCGCTCCCGGGTCGTTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000792 Transcription regulator LuxR, C-terminal (Domain)
 [870-884]  2.00000075217457e-06 PR00038 [884-900]  2.00000075217457e-06 PR00038 [900-912]  2.00000075217457e-06 PR00038
PR00038   HTHLUXR
 [867-924]  4.40000933643891e-21 SM00421
SM00421   HTH_LUXR
 [863-927]  PS50043
PS50043   HTH_LUXR_2
 [868-922]  6.50000000000001e-13 PF00196
PF00196   GerE
IPR011990 Tetratricopeptide-like helical (Domain)
 [620-878]  2.7e-09 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [879-923]  1e-18 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
 [848-924]  9.20000434662057e-16 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP No significant hit
TMHMM No significant hit