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CDS information : Pyrlo_00160


close this sectionLocation

Organism
StrainATCC 31673 (=NBRC 14294)
Entry namePyrrolomycin
Contig
Start / Stop / Direction18,641 / 20,395 / + [in whole cluster]
18,641 / 20,395 / + [in contig]
Location18641..20395 [in whole cluster]
18641..20395 [in contig]
TypeCDS
Length1,755 bp (584 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category3.4 other modification
Productputative halogenase
Product (GenBank)halogenase
Gene
Gene (GenBank)pyr16
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[17158935] Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065. (Antimicrob Agents Chemother. , 2007)
Related Reference
ACC
Q71ME2
PmId
[15321684] A novel halogenase gene from the pentachloropseudilin producer Actinoplanes sp. ATCC 33002 and detection of in vitro halogenase activity. (FEMS Microbiol Lett. , 2004)
ACC
Q9X3Q8
NITE
Pyolu_00010
PmId
[10094695] Characterization of the pyoluteorin biosynthetic gene cluster of Pseudomonas fluorescens Pf-5. (J Bacteriol. , 1999)
[16162666] Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. (Proc Natl Acad Sci U S A. , 2005)

close this sectionSequence

selected fasta
>putative halogenase [halogenase]
MPRSTRTTKSTKIERPDTDVVILGSGLAGAAMAAVLSRNGANVLILDAGTHPRFAIGEST
IPYTSMLMRLVSERYDVPEIKYLTTFENVQGKITSTCGIKKNFGFLYHREGERQKYHEAH
QFPIPRITHIENHFFRQDIDAWMLNVAVKYGARIQQRTRIVDVAFDDAGGTLTDDQGRTY
RTRFVVDASGFRSPLAEKLDLRDQPTRMRHHSRSIFTHMVGVPDYDDLLPKVSHGHPTRW
AQGTLHHIYEGGWGWVIPFNNHARATNPLVSVGFSFDPRIHPDFDGTPEEEFRAFIDRFP
DIRRQFVDATAVRPWVRTGRLQYSSSKTVGARWCLTSHAAGFVDALFSRGLSNSFEIINA
LTWRLLEALRDDDFTEERFEYVQRLEQGLLDFNDNLVANAYTSFGHYDLWDTWFRVWSLG
QILATFEINSTYAKFLESHDVRDLTRLEGIAPDGSIPSYAPARELMNFVSDQVSQVQEKR
NDAGVAAKAIMEALQKADFVPPAFGLADADNRWFNASTKKVMETIKWARNSAPREIGTLV
DEGLTLFIKKRLSRDEFDLAEEAKHIVAAWPVIGRKFRSPSLSY
selected fasta
>putative halogenase [halogenase]
ATGCCCAGGAGCACCAGGACCACAAAGTCGACCAAGATCGAGCGCCCAGACACCGATGTG
GTGATCCTCGGCTCCGGGCTCGCCGGAGCGGCGATGGCCGCGGTGCTGTCCCGCAACGGT
GCCAATGTACTGATCCTCGATGCGGGCACCCACCCGCGGTTCGCCATTGGGGAATCGACC
ATCCCGTATACGTCCATGCTCATGCGTCTGGTCAGTGAGCGGTATGACGTTCCCGAGATC
AAGTACCTCACCACGTTCGAGAACGTGCAGGGAAAGATCACCAGTACCTGCGGCATCAAG
AAGAACTTCGGGTTCCTCTACCACCGCGAGGGCGAGCGCCAGAAGTACCACGAGGCGCAC
CAGTTCCCGATCCCGCGGATCACGCACATCGAGAACCACTTCTTCCGCCAGGACATCGAT
GCCTGGATGCTCAATGTCGCGGTGAAGTACGGCGCCCGTATCCAACAGCGCACCCGCATC
GTGGACGTGGCGTTCGACGACGCCGGTGGCACCCTCACCGATGACCAGGGCAGGACCTAC
CGGACCCGGTTCGTGGTGGACGCGAGCGGCTTCAGGTCCCCCCTGGCCGAGAAGCTCGAC
CTGCGTGACCAGCCCACCCGGATGCGGCACCACTCGCGCTCGATCTTCACCCACATGGTG
GGCGTGCCGGACTACGACGACCTGCTGCCGAAGGTCTCCCACGGTCACCCCACCCGGTGG
GCCCAGGGCACCCTGCACCACATCTACGAGGGCGGCTGGGGCTGGGTCATCCCGTTCAAC
AACCACGCCCGGGCGACCAACCCGCTGGTCAGCGTCGGGTTCAGCTTCGACCCGCGGATC
CACCCGGACTTCGACGGCACCCCGGAGGAGGAGTTCCGGGCCTTCATCGACCGTTTCCCC
GACATCCGGCGCCAGTTCGTCGACGCCACCGCGGTCCGCCCCTGGGTGCGCACCGGCCGG
TTGCAGTACTCCTCGAGCAAGACCGTCGGTGCCCGCTGGTGCCTGACCTCGCACGCGGCC
GGCTTCGTGGACGCGCTGTTCTCCCGGGGCCTGTCCAACTCCTTCGAGATCATCAACGCG
CTGACCTGGCGGCTGCTCGAGGCTCTGCGCGACGACGACTTCACCGAGGAGCGCTTCGAG
TACGTCCAGCGGCTCGAGCAGGGCCTGCTGGACTTCAACGACAACCTGGTGGCGAACGCG
TACACGTCGTTCGGCCACTACGACCTGTGGGACACCTGGTTCCGGGTCTGGTCTCTGGGG
CAGATCCTGGCCACCTTCGAGATCAACTCCACCTACGCGAAGTTCCTGGAGTCCCACGAC
GTGCGGGACCTCACCCGGCTGGAGGGGATCGCCCCCGACGGGTCCATCCCGAGCTACGCA
CCCGCCCGCGAGCTGATGAACTTCGTCAGCGACCAGGTGAGCCAGGTGCAGGAGAAGCGC
AACGACGCGGGGGTGGCCGCCAAGGCCATCATGGAGGCGTTGCAGAAGGCGGACTTCGTG
CCGCCGGCGTTCGGCCTGGCCGACGCGGACAACCGCTGGTTCAACGCGAGCACCAAGAAG
GTCATGGAGACCATCAAGTGGGCCCGCAACTCCGCACCCAGGGAGATCGGGACGCTGGTG
GACGAGGGCCTGACCCTGTTCATCAAGAAGCGGCTGTCCCGCGACGAGTTCGACCTCGCC
GAGGAGGCCAAGCACATCGTGGCCGCCTGGCCCGTGATCGGTAGGAAGTTCCGTTCCCCG
TCGCTGTCGTACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR003042 Aromatic-ring hydroxylase-like (Domain)
 [19-41]  2.2999993566538e-06 PR00420 [181-196]  2.2999993566538e-06 PR00420
PR00420   RNGMNOXGNASE
SignalP
 [1-33]  0.995 Signal
Bacteria, Gram-negative   
 [1-33]  0.723 Signal
Bacteria, Gram-positive   
 [1-33]  0.23 Signal
Eukaryota   
TMHMM
 [20-37]  Transmembrane (i-o)
Transmembrane 1