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CDS information : Rifam_00600


close this sectionLocation

Organism
StrainS699
Entry nameRifamycin
Contig
Start / Stop / Direction102,476 / 102,967 / + [in whole cluster]
102,476 / 102,967 / + [in contig]
Location102476..102967 [in whole cluster]
102476..102967 [in contig]
TypeCDS
Length492 bp (163 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.2 modification addition of starter unit
Productputative aminodehydroquinate dehydratase
Product (GenBank)aminodehydroquinate dehydratase
Gene
Gene (GenBank)rifJ
EC number
Keyword
  • AHBA
Note
Note (GenBank)
  • RifJ
Reference
ACC
PmId
[9512878] Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699. (Chem Biol. , 1998)
[11278540] Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699. (J Biol Chem. , 2001)
Related Reference
ACC
P43877
PmId
[8170389] Characterization of a 3-dehydroquinase gene from Actinobacillus pleuropneumoniae with homology to the eukaryotic genes qa-2 and QUTE. (Mol Microbiol. , 1994)

close this sectionSequence

selected fasta
>putative aminodehydroquinate dehydratase [aminodehydroquinate dehydratase]
MVQAPCRTRCVPLPDVLLLNGPNLGVLGRREPEIYGTDTLADIEKAVAEEVRPRGWTVVP
VQRDGEGELVGAIHQHRDTTVGAIVNPGALMIAGWSLRDALASYEPPWIEVHLSNVWARE
QFRHDSVIAPLASGVVVGLGAFGYRLAAQALLHLSAESPNGLR
selected fasta
>putative aminodehydroquinate dehydratase [aminodehydroquinate dehydratase]
GTGGTCCAGGCCCCCTGCCGAACGAGGTGTGTCCCGTTGCCCGACGTCCTGCTGCTGAAC
GGTCCCAACCTGGGTGTGCTGGGCCGGCGCGAGCCCGAGATCTACGGCACCGACACGCTC
GCCGACATCGAAAAGGCGGTCGCCGAGGAGGTGCGGCCCCGCGGCTGGACCGTCGTCCCG
GTCCAGCGCGACGGCGAGGGCGAGCTGGTCGGCGCGATCCACCAGCACCGCGACACGACG
GTCGGCGCGATCGTCAACCCCGGTGCGCTGATGATCGCCGGCTGGAGCCTGCGCGACGCG
CTGGCCAGCTACGAGCCGCCGTGGATCGAGGTCCACCTGAGCAACGTGTGGGCGCGCGAG
CAGTTCCGGCACGACTCGGTCATCGCCCCGCTGGCGAGCGGGGTGGTGGTCGGCCTCGGC
GCCTTCGGCTACCGCCTGGCCGCACAGGCGTTGCTGCACCTGTCCGCCGAATCGCCGAAT
GGGCTCCGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001874 Dehydroquinase, class II (Family)
 [14-156]  2.89999999999999e-54 G3DSA:3.40.50.9100
G3DSA:3.40.50.9100   DHquinase_II
 [12-157]  3.19999899046355e-65 PIRSF001399
PIRSF001399   DHquinase_II
 [15-152]  4.6e-49 PF01220
PF01220   DHquinase_II
 [8-156]  3.49999466863949e-49 SSF52304
SSF52304   DHquinase_II
 [29-160]  PD004527
PD004527   DHquinase_II
IPR018509 Dehydroquinase, class II, conserved site (Conserved_site)
 [19-36]  PS01029
PS01029   DEHYDROQUINASE_II
SignalP No significant hit
TMHMM
 [126-148]  Transmembrane (i-o)
Transmembrane 1