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CDS information : Rubra_00500


close this sectionLocation

Organism
StrainNRRL 3061 (=NBRC 14000)
Entry nameRubradirin
Contig
Start / Stop / Direction91,448 / 92,320 / + [in whole cluster]
91,448 / 92,320 / + [in contig]
Location91448..92320 [in whole cluster]
91448..92320 [in contig]
TypeCDS
Length873 bp (290 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative transcriptional regulator
Product (GenBank)putative transcription activator
Gene
Gene (GenBank)rubRg3
EC number
Keyword
  • SARP family
Note
Note (GenBank)
Reference
ACC
PmId
[18080113] Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061. (Arch Microbiol. , 2008)
Related Reference
ACC
P25047
NITE
Adria_00210
PmId
[1729206] Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius. (J Bacteriol. , 1992)
[7868593] Functional characterization and transcriptional analysis of the dnrR1 locus, which controls daunorubicin biosynthesis in Streptomyces peucetius. (J Bacteriol. , 1995)
[8971703] Purification and characterization of the DNA-binding protein DnrI, a transcriptional factor of daunorubicin biosynthesis in Streptomyces peucetius. (Mol Microbiol. , 1996)
[16545946] Feedback regulation of doxorubicin biosynthesis in Streptomyces peucetius. (Res Microbiol. , 2006)
[20529134] Modulation of dnrN expression by intracellular levels of DnrO and daunorubicin in Streptomyces peucetius. (FEMS Microbiol Lett. , 2010)
[20158521] Daunorubicin efflux in Streptomyces peucetius modulates biosynthesis by feedback regulation. (FEMS Microbiol Lett. , 2010)
ACC
Q83X29
PmId
[12791134] The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism. (Mol Microbiol. , 2003)
[20378964] Regulation of lankamycin biosynthesis in Streptomyces rochei by two SARP genes, srrY and srrZ. (Biosci Biotechnol Biochem. , 2010)

close this sectionSequence

selected fasta
>putative transcriptional regulator [putative transcription activator]
MKFRVLGPFESSIDGTPSTPSATRVRWTLALLLLRANQVVDRGCIIQELWGENPPRRAVT
AAQTYIYHLRKMYLRCAGRPGEGEFIETRPPGYLLRCEESEIDAFVFERLSAEGAAAYAA
GDAERAARRLRQALALWRGRVLADITAGPVLTPHIRKLEEVRTRTVRTRILADLRLGRHH
ELIPELRLAAAEHPFDEWFHEQLMIALSEAGRRAEALDAYRELRRTLDQNLGIEPSHTLQ
QLQHDVLVGAVRRPDRAKEAVAHGAAHGRAGQRHRRRGPEGQARAKEAQS
selected fasta
>putative transcriptional regulator [putative transcription activator]
ATGAAATTCCGAGTACTCGGTCCCTTCGAGAGTTCGATAGACGGCACGCCGAGCACACCC
AGCGCGACCCGGGTGCGCTGGACGCTTGCCCTGCTGCTGCTGCGGGCCAACCAGGTGGTC
GACCGGGGCTGCATCATCCAGGAACTGTGGGGGGAGAACCCCCCGCGCCGGGCGGTCACC
GCGGCGCAGACGTACATCTATCACTTGCGCAAGATGTACCTGCGGTGCGCCGGCCGGCCC
GGTGAGGGCGAGTTCATCGAGACCCGCCCGCCGGGTTACCTGCTGCGGTGCGAGGAGTCG
GAGATCGACGCGTTCGTCTTCGAGCGGCTCAGTGCGGAAGGTGCCGCCGCCTACGCCGCG
GGCGACGCGGAGCGGGCGGCCCGCCGTCTGCGGCAGGCGCTCGCGCTGTGGCGCGGCCGG
GTGCTCGCCGACATCACCGCGGGCCCGGTGCTGACCCCGCACATCCGGAAGCTGGAGGAG
GTGCGCACCCGGACGGTCCGCACCCGGATCCTGGCCGACCTGCGGCTCGGCCGGCACCAC
GAACTCATCCCCGAGCTGCGGCTGGCCGCGGCCGAGCATCCCTTCGACGAGTGGTTCCAC
GAACAGCTGATGATCGCCCTGAGCGAGGCGGGCCGGCGCGCGGAAGCCCTGGACGCCTAC
CGCGAACTGCGGCGCACGCTGGACCAGAACCTGGGCATCGAACCGTCGCACACGCTCCAG
CAGCTCCAGCACGATGTGCTCGTGGGCGCCGTGCGCCGCCCGGACCGGGCCAAGGAGGCC
GTAGCGCACGGGGCGGCACACGGCCGCGCCGGACAGCGACACCGCAGGCGAGGGCCGGAA
GGCCAGGCCAGGGCGAAGGAGGCCCAGTCATGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001867 Signal transduction response regulator, C-terminal (Domain)
 [15-95]  8.50000225010472e-07 SM00862
SM00862   Trans_reg_C
 [19-95]  6.50000000000001e-10 PF00486
PF00486   Trans_reg_C
IPR005158 Bacterial transcriptional activator domain (Domain)
 [102-247]  3.29999999999997e-48 PF03704
PF03704   BTAD
 [102-247]  7.90003079443025e-54 SM01043
SM01043   BTAD
IPR011990 Tetratricopeptide-like helical (Domain)
 [110-225]  3.1e-06 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
 [29-98]  3.1e-06 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
 [1-96]  2.89999717862184e-10 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP
 [1-42]  0.295 Signal
Bacteria, Gram-positive   
TMHMM No significant hit