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CDS information : Sch475_00240


close this sectionLocation

Organism
StrainSCC-2136
Entry nameSch 47554
Contig
Start / Stop / Direction37,175 / 35,871 / - [in whole cluster]
37,175 / 35,871 / - [in contig]
Locationcomplement(35871..37175) [in whole cluster]
complement(35871..37175) [in contig]
TypeCDS
Length1,305 bp (434 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productputative pyridoxamine 5'-monophosphate-dependent NDP-hexose C-3 dehydratase
Product (GenBank)putative NDP-hexose 3-dehydratase
Gene
Gene (GenBank)schS3
EC number
Keyword
  • amicetose
Note
Note (GenBank)
Reference
ACC
PmId
[17085966] Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: cloning, sequencing, and characterization. (Mol Cells. , 2006)
Related Reference
ACC
Q9ALN8
NITE
Spino_00050
PmId
[17076492] Characterization of SpnQ from the spinosyn biosynthetic pathway of Saccharopolyspora spinosa: mechanistic and evolutionary implications for C-3 deoxygenation in deoxysugar biosynthesis. (J Am Chem Soc. , 2006)
[18345667] In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa. (J Am Chem Soc. , 2008)

close this sectionSequence

selected fasta
>putative pyridoxamine 5'-monophosphate-dependent NDP-hexose C-3 dehydratase [putative NDP-hexose 3-dehydratase]
MSDPKETVLDAVRAYHEVSTPAREFVPGTTEIWPSGAVLEVEDRVALVEAALDMRIAAGR
SQRKFESAFARRMKRRKAHLTNSGSSANLLAVSALTSSHLEDRRLRPGDEIITVAAGFPT
TVNPILQNGLVPVFVDVDLTTYNATADKVAAAIGPKTRAIIIAHALGNPFEVTAIAQLAE
EHDLFLIEDNCDAVGSLYDGQLTGTFGDMTTVSFYPAHHLTMGEGGCVLTSNLALARIVE
SLRDWGRDCWCEPGENDKCLKRFKYQMGTLPAGYDHKYIFSHVGYNLKATDIQAALGLTQ
LAKLDDFIDARKRNWRRLREGLDGVPGLILPEATPRSDPSWFGFVITVDPEAPFGRAELV
SHLEDRKIGTRRLFAGNLTRHPAYIDQPHRVVGDLTNSDIITEHTFWIGVYPALTDEMLD
YVTASIKEFVAARG
selected fasta
>putative pyridoxamine 5'-monophosphate-dependent NDP-hexose C-3 dehydratase [putative NDP-hexose 3-dehydratase]
ATGAGCGACCCCAAGGAAACGGTGCTCGACGCGGTCCGCGCGTACCACGAAGTCAGCACA
CCGGCACGGGAGTTCGTGCCCGGCACGACGGAGATCTGGCCCTCGGGCGCGGTCCTCGAG
GTGGAGGACCGGGTGGCGCTGGTGGAAGCCGCCCTCGACATGCGGATCGCCGCCGGGCGC
AGCCAGCGCAAATTCGAGTCGGCGTTCGCCCGGCGGATGAAGCGGCGCAAGGCCCATCTC
ACCAACTCCGGCTCCTCGGCGAACCTCCTCGCCGTCTCGGCGCTCACCTCGTCCCATCTG
GAGGACCGGCGGCTGAGGCCGGGCGACGAGATCATCACCGTCGCGGCGGGCTTCCCCACC
ACGGTCAACCCGATCCTGCAGAACGGGCTCGTACCGGTCTTCGTCGATGTGGACCTGACG
ACGTACAACGCGACCGCGGACAAGGTGGCCGCCGCCATCGGGCCCAAGACCCGGGCGATC
ATCATCGCGCACGCGCTCGGCAACCCCTTCGAGGTCACCGCGATCGCCCAACTCGCCGAG
GAACACGACCTGTTCCTCATCGAGGACAACTGTGACGCGGTCGGCTCGCTGTACGACGGA
CAGCTCACCGGCACCTTCGGCGACATGACCACGGTCAGCTTCTACCCGGCGCACCACCTC
ACGATGGGCGAGGGCGGCTGTGTGCTGACCTCGAACCTGGCGCTCGCCCGGATCGTGGAG
TCGCTGCGGGACTGGGGCCGGGACTGCTGGTGCGAGCCGGGCGAGAACGACAAGTGCCTC
AAGCGGTTCAAGTACCAGATGGGCACCCTGCCGGCCGGCTACGACCACAAGTACATCTTC
TCGCACGTCGGTTACAACCTGAAGGCCACCGACATCCAGGCCGCCCTCGGTCTGACCCAG
CTCGCCAAGCTCGACGACTTCATCGACGCCCGCAAGCGCAACTGGCGGCGGCTGCGCGAG
GGCCTGGACGGCGTACCCGGGCTGATCCTGCCCGAGGCCACGCCCCGCTCCGACCCGAGC
TGGTTCGGATTCGTCATCACCGTGGACCCCGAAGCCCCGTTCGGCCGGGCGGAGTTGGTG
TCCCACCTGGAGGACCGCAAGATCGGCACCCGGCGGCTGTTCGCCGGCAATCTCACCCGG
CATCCCGCCTACATCGACCAGCCCCACCGTGTGGTCGGCGACCTGACCAACAGCGACATC
ATCACCGAGCACACGTTCTGGATCGGGGTCTACCCGGCGCTCACCGACGAGATGCTCGAC
TACGTGACCGCCTCGATCAAGGAGTTCGTGGCCGCGCGCGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase (Family)
 [1-434]  2.39999798157263e-112 PIRSF000390
PIRSF000390   PLP_StrS
 [44-426]  8.29999999999993e-100 PF01041
PF01041   DegT_DnrJ_EryC1
IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (Domain)
 [32-302]  4.40000000000003e-69 G3DSA:3.40.640.10
G3DSA:3.40.640.10   PyrdxlP-dep_Trfase_major_sub1
IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (Domain)
 [303-427]  4.70000000000003e-51 G3DSA:3.90.1150.10
G3DSA:3.90.1150.10   PyrdxlP-dep_Trfase_major_sub2
IPR015424 Pyridoxal phosphate-dependent transferase, major domain (Domain)
 [29-433]  1.19999063421924e-96 SSF53383
SSF53383   PyrdxlP-dep_Trfase_major
SignalP No significant hit
TMHMM No significant hit