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CDS information : Strply_00120


close this sectionLocation

Organism
StrainNRRL 2433 (=NBRC 13058)
Entry nameStreptolydigin
Contig
Start / Stop / Direction15,342 / 14,101 / - [in whole cluster]
15,342 / 14,101 / - [in contig]
Locationcomplement(14101..15342) [in whole cluster]
complement(14101..15342) [in contig]
TypeCDS
Length1,242 bp (413 aa)
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close this sectionAnnotation

Category3.3 modification reduction
Productputative cytochrome P450
Product (GenBank)cytochrome P450
Gene
Gene (GenBank)slgO2
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[19875077] Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives. (Chem Biol. , 2009)
[22569159] Novel compounds produced by Streptomyces lydicus NRRL 2433 engineered mutants altered in the biosynthesis of streptolydigin. (J Antibiot (Tokyo). , 2012)
Related Reference
ACC
P33271
PmId
[1732208] Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase. (J Bacteriol. , 1992)

close this sectionSequence

selected fasta
>putative cytochrome P450 [cytochrome P450]
MSERTPVADAFGDADFMQDPHAVYRRLREQGPVHRTTLPKGVPLFGGLPVWVVSTYSAVR
AALTDPRLSTDLKHTSALFARHGTDTAGGAFGAVLARHMLHSDQPDHTRLRKLVNKAFTP
GAVDRLRPRIEDITSGLLDAMKGREQVDLLEEFAFPLPVTVICELLGVPEADRADFTRWS
QRLVSGPSAEEVAAAQASMVGYLTELTAAKRAEPQDDILSALVQARDEGDRLADSELVPM
AFLLLVGGHETTTNLIGNGTLHLLRDRTKLRALLDDPALLPNAVEEFLRFEGPIKHATFR
YTTDEVEVDGVRIPAGELVLVSLVSANRDGERFTDPDRLDLTRAPGGNLAFGHGIHYCVG
APLARLEAQIAFRQLLERYPDMELAAEPAELYWRASTLMRGLHSLPVRLGGGG
selected fasta
>putative cytochrome P450 [cytochrome P450]
ATGAGCGAGCGGACACCGGTCGCGGACGCCTTCGGCGACGCCGACTTCATGCAGGACCCG
CACGCGGTCTACCGGCGGCTGCGCGAGCAGGGCCCGGTGCACCGCACCACGCTCCCCAAG
GGCGTACCGCTCTTCGGCGGGCTGCCGGTGTGGGTGGTCAGCACGTACTCCGCGGTGCGG
GCCGCGCTGACCGACCCCCGGCTGAGCACCGACCTCAAACACACCAGCGCGCTGTTCGCC
CGGCACGGCACCGACACCGCCGGCGGCGCGTTCGGCGCGGTGCTCGCCCGGCACATGCTC
CACTCCGACCAGCCGGACCACACCCGGCTGCGCAAACTGGTCAACAAGGCGTTCACCCCG
GGCGCCGTGGACCGGCTGCGGCCGCGCATCGAGGACATCACCAGCGGCCTGCTGGACGCC
ATGAAGGGGCGCGAACAGGTCGACCTGCTGGAGGAGTTCGCCTTCCCGCTGCCGGTCACC
GTCATCTGCGAACTGCTCGGCGTCCCCGAGGCCGACCGGGCCGACTTCACGCGCTGGTCC
CAGCGCCTGGTCTCCGGCCCCTCCGCCGAGGAGGTCGCCGCCGCCCAGGCGTCGATGGTC
GGCTACCTGACCGAGCTGACCGCGGCCAAGCGCGCCGAGCCGCAGGACGACATCCTCAGC
GCCCTGGTCCAGGCCCGCGACGAGGGCGACCGCCTCGCCGACAGCGAACTGGTCCCGATG
GCGTTCCTGCTGCTGGTCGGCGGACACGAGACGACCACCAACCTGATCGGCAACGGCACC
CTCCATCTGCTGCGCGACCGCACCAAGCTGCGTGCCCTGCTCGACGATCCGGCCCTGCTG
CCCAACGCGGTCGAGGAGTTCCTGCGGTTCGAAGGGCCCATCAAGCACGCCACGTTCCGG
TACACCACCGACGAGGTCGAGGTGGACGGCGTCCGCATCCCCGCCGGGGAACTGGTCCTC
GTTTCACTGGTGTCCGCCAATCGCGACGGCGAGCGCTTCACCGACCCGGACCGGCTCGAC
CTGACCCGCGCGCCCGGCGGCAACCTGGCCTTCGGCCACGGCATCCACTACTGCGTCGGC
GCGCCCCTCGCCCGCCTCGAAGCGCAGATCGCCTTCCGCCAACTCCTTGAACGCTACCCG
GACATGGAGCTGGCGGCCGAGCCGGCCGAGCTGTACTGGCGGGCCAGCACCCTGATGCGG
GGCCTGCACTCGCTGCCCGTCCGCCTCGGGGGCGGCGGATGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001128 Cytochrome P450 (Family)
 [13-409]  1.20000000000001e-120 G3DSA:1.10.630.10
G3DSA:1.10.630.10   Cyt_P450
 [15-409]  1.90000694315261e-105 SSF48264
SSF48264   Cytochrome_P450
 [191-379]  1.8e-18 PF00067
PF00067   p450
IPR002397 Cytochrome P450, B-class (Family)
 [102-113]  4.50001022902825e-61 PR00359 [148-164]  4.50001022902825e-61 PR00359 [165-180]  4.50001022902825e-61 PR00359 [201-223]  4.50001022902825e-61 PR00359 [282-293]  4.50001022902825e-61 PR00359 [300-327]  4.50001022902825e-61 PR00359 [328-343]  4.50001022902825e-61 PR00359 [349-358]  4.50001022902825e-61 PR00359 [358-369]  4.50001022902825e-61 PR00359
PR00359   BP450
IPR017972 Cytochrome P450, conserved site (Conserved_site)
 [351-360]  PS00086
PS00086   CYTOCHROME_P450
SignalP No significant hit
TMHMM No significant hit