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CDS information : Teicp2_00360


close this sectionLocation

Organism
StrainATCC 31121 (=NBRC 13999)
Entry nameTeicoplanin
Contig
Start / Stop / Direction66,949 / 68,004 / + [in whole cluster]
66,949 / 68,004 / + [in contig]
Location66949..68004 [in whole cluster]
66949..68004 [in contig]
TypeCDS
Length1,056 bp (351 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.1 modification addition of extender units
Productputative phospho-2-dehydro-3-deoxyheptonate aldolase
putative 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
putative DAHP synthase
Product (GenBank)phospho-2-dehydro-3-deoxyheptonate aldolase, AroA type
Gene
Gene (GenBank)tcp27
EC number2.5.1.54
Keyword
  • Bht
  • Hpg
  • Dpg
  • Tyr
Note
Note (GenBank)
Reference
ACC
PmId
[14702401] Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus. (Microbiology. , 2004)
Related Reference
ACC
Q6ZZH9
NITE
Teicp_00290
PmId
[15113000] Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase. (Chem Biol. , 2004)
ACC
Q9WYH8
PmId
[12743122] Thermotoga maritima 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase: the ancestral eubacterial DAHP synthase? (J Biol Chem. , 2003)

close this sectionSequence

selected fasta
>putative phospho-2-dehydro-3-deoxyheptonate aldolase [phospho-2-dehydro-3-deoxyheptonate aldolase, AroA type]
MVVVMAPEATSADVDAVVRLVESVGGQAFVSRGLSRTIVGLVGDVADFEALNLGSLAGVL
RVIRVSVPYKLVSREHHPARSVIRAGGVPIGPGTLTVIAGPCAVESPEQTLEAARMARSA
GASMLRGGAFKPRTSPYSYQGLGERGLRILADVRAETGLAVVTEVIDPGSVDMVASYADM
LQIGARNMQNFALLQAVGSAGKPVLLKRGFSATIEEWLSAAEYIAQRGNLNIVLCERGIR
TFETATRNTLDISAVPVAQRLSHLPVIVDPSHSGGRRDLVVPLTRAAIAVGADGLLIDVH
PEPKTALCDGDQALPEADIREIADIVASLPAFLGREPAVPSGEFRHVPAAV
selected fasta
>putative phospho-2-dehydro-3-deoxyheptonate aldolase [phospho-2-dehydro-3-deoxyheptonate aldolase, AroA type]
ATGGTCGTTGTGATGGCGCCGGAGGCCACTTCGGCGGATGTGGACGCGGTCGTCCGGCTG
GTCGAGTCGGTGGGCGGGCAGGCGTTCGTCAGCCGCGGGCTGTCCCGGACCATCGTCGGC
CTGGTCGGCGACGTGGCCGACTTCGAGGCGCTCAACCTGGGCAGCCTGGCGGGCGTGCTG
CGGGTGATCCGGGTGTCGGTGCCGTACAAGCTGGTCAGCCGGGAGCACCACCCGGCGCGC
TCGGTGATCCGGGCCGGCGGCGTGCCGATCGGTCCCGGCACGCTGACCGTGATCGCCGGG
CCGTGCGCGGTGGAGTCCCCGGAGCAGACGCTGGAGGCGGCCCGGATGGCGCGCTCGGCC
GGGGCCTCGATGCTGCGCGGCGGGGCGTTCAAGCCGCGGACCTCACCGTACTCCTACCAG
GGGTTGGGGGAGCGGGGCCTGCGCATCCTGGCCGACGTGCGGGCCGAGACGGGGCTCGCC
GTGGTCACCGAGGTGATCGATCCCGGCAGTGTGGACATGGTCGCGTCGTACGCCGACATG
CTCCAGATCGGCGCCCGGAACATGCAGAATTTCGCGCTGCTGCAGGCGGTCGGGTCGGCC
GGCAAACCGGTGCTGCTCAAGCGCGGGTTCAGCGCCACGATCGAGGAATGGCTCAGCGCC
GCCGAGTACATCGCGCAGCGCGGCAATCTGAACATCGTGTTGTGTGAGCGCGGGATCCGG
ACGTTCGAGACCGCTACCCGTAACACGCTGGACATCAGCGCGGTGCCGGTCGCCCAGCGG
CTCTCCCACCTGCCGGTGATCGTGGATCCGTCGCACTCCGGCGGCCGCCGCGATCTGGTG
GTGCCGCTGACCCGCGCGGCGATCGCGGTGGGCGCGGACGGGTTGCTCATCGACGTCCAC
CCGGAGCCGAAGACCGCTCTGTGCGACGGTGACCAGGCGCTGCCGGAAGCCGACATCCGG
GAGATCGCCGACATCGTGGCGAGCCTGCCCGCGTTCCTGGGGCGGGAGCCGGCCGTGCCC
TCGGGTGAATTCCGACACGTTCCCGCCGCGGTGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR006218 DAHP synthetase I/KDSA (Domain)
 [88-326]  7.5e-77 PF00793
PF00793   DAHP_synth_1
IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 (Domain)
 [71-324]  8.70000000000003e-117 TIGR01361
TIGR01361   DAHP_synth_Bsub
IPR013785 Aldolase-type TIM barrel (Domain)
 [94-336]  1.69999999999998e-97 G3DSA:3.20.20.70
G3DSA:3.20.20.70   Aldolase_TIM
SignalP No significant hit
TMHMM No significant hit