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CDS information : Teicp2_00450


close this sectionLocation

Organism
StrainATCC 31121 (=NBRC 13999)
Entry nameTeicoplanin
Contig
Start / Stop / Direction79,108 / 80,205 / + [in whole cluster]
79,108 / 80,205 / + [in contig]
Location79108..80205 [in whole cluster]
79108..80205 [in contig]
TypeCDS
Length1,098 bp (365 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.1 modification addition of extender units
Productputative aminotransferase
Product (GenBank)HpgT aminotransferase
Genetcp36
hpgT
Gene (GenBank)tcp36
EC number2.6.1.-
Keyword
  • Hpg
  • Dpg
Note
Note (GenBank)
Reference
ACC
PmId
[14702401] Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus. (Microbiology. , 2004)
Related Reference
ACC
Q6ZZH0
NITE
Teicp_00380
PmId
[15113000] Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase. (Chem Biol. , 2004)
ACC
O52815
NITE
Chlor_00180
PmId
[11137816] Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics. (Chem Biol. , 2000)
ACC
Q939Y4
NITE
Balhi_00210
PmId
[11495926] A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine. (J Biol Chem. , 2001)

close this sectionSequence

selected fasta
>putative aminotransferase [HpgT aminotransferase]
MESSALRKSELHPSISDPVLDTMNFLNEVTLRYPEAISFAPGRPYDGFFQTEEVLAHLRR
FLDHLADQGASPAQVRTAVYQYGPTAGQIREIIADSLRRDEGIDVPAESIVVTVGAQEAM
MLVVRALIRDPRDVLLVPSPCYVGITGVARLLDVTLGPVPESPDGFSLENVAAAIRAQRA
AGRRPRAFYLVPDHANPSGTTLSESDRAGLLHLAAKEDLLILEDTPYRLVSPGEPVRTLK
ALDRRRSVVHLGSYSKTIFPGARVGFAVADQTVVGDDGRTGLLADELSKIKSMVTVNTSS
LSQAVVAGALLAAGGRVSELNAKAAGHYGDAMRRVLDRLADRLPAARRAELGARIRTDEA
GTTGA
selected fasta
>putative aminotransferase [HpgT aminotransferase]
GTGGAATCGTCTGCGCTGCGCAAGTCGGAATTGCATCCGAGCATTTCGGACCCGGTTCTG
GACACGATGAATTTCCTCAACGAGGTGACCCTGCGCTATCCCGAGGCGATCTCGTTCGCG
CCGGGCCGCCCGTACGACGGCTTCTTCCAGACCGAGGAGGTCCTCGCCCACCTGCGCCGC
TTTCTCGACCACCTGGCCGACCAGGGCGCCTCGCCCGCGCAGGTGCGCACGGCGGTCTAC
CAGTACGGCCCGACCGCCGGCCAGATCCGCGAGATCATCGCCGACTCGCTGCGCCGGGAC
GAGGGGATCGACGTGCCGGCCGAGTCCATCGTGGTCACCGTCGGCGCGCAGGAGGCGATG
ATGCTGGTCGTCCGCGCGCTGATCCGTGACCCGCGGGACGTGCTGCTGGTGCCCAGCCCC
TGCTACGTGGGCATCACCGGGGTGGCCCGGCTGCTCGACGTGACGCTCGGCCCGGTGCCC
GAGTCGCCGGACGGCTTCTCCCTGGAGAACGTGGCGGCGGCGATCCGGGCGCAGCGGGCC
GCCGGGCGCCGGCCGCGAGCCTTCTACCTGGTGCCCGACCACGCCAACCCGTCCGGCACC
ACGCTGTCCGAGTCGGACCGGGCCGGGTTGCTGCACCTGGCCGCGAAGGAGGATCTGCTG
ATCCTGGAGGACACCCCGTACCGGCTGGTCAGCCCCGGCGAGCCGGTGCGCACGCTGAAG
GCGCTGGACCGCCGCCGCTCGGTGGTGCACCTGGGGTCGTACTCAAAAACGATCTTTCCG
GGCGCGCGGGTGGGCTTCGCCGTGGCCGACCAGACGGTGGTCGGCGACGACGGCCGGACC
GGCCTGCTCGCCGACGAGCTCTCGAAGATCAAGAGCATGGTGACGGTCAACACCTCGTCG
CTGAGCCAGGCGGTGGTGGCCGGCGCGCTGCTCGCGGCCGGCGGCCGGGTCTCCGAGCTG
AACGCCAAGGCGGCCGGGCACTACGGCGACGCCATGCGCCGGGTGCTCGACCGGCTCGCC
GACCGGTTGCCCGCGGCGCGGCGCGCGGAGCTGGGCGCGCGGATCCGTACCGACGAGGCG
GGGACGACGGGCGCGTAA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR004839 Aminotransferase, class I/classII (Domain)
 [80-324]  8.70000000000003e-18 PF00155
PF00155   Aminotran_1_2
IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (Domain)
 [75-310]  1.29999999999998e-47 G3DSA:3.40.640.10
G3DSA:3.40.640.10   PyrdxlP-dep_Trfase_major_sub1
IPR015424 Pyridoxal phosphate-dependent transferase, major domain (Domain)
 [1-361]  2.39999798157265e-54 SSF53383
SSF53383   PyrdxlP-dep_Trfase_major
SignalP No significant hit
TMHMM No significant hit