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CDS information : Vanco_00180


close this sectionLocation

Organism
StrainATCC 19795 (=NBRC 12806)
Entry nameVancomycin
Contig
Start / Stop / Direction45,500 / 46,726 / + [in whole cluster]
45,500 / 46,726 / + [in contig]
Location45500..46726 [in whole cluster]
45500..46726 [in contig]
TypeCDS
Length1,227 bp (408 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productputative dTDP-3-amino-4-keto-2,3,6-trideoxy-D-glucose C-3 C-methyltransferase
Product (GenBank)putative C-3 methyltransferase
Gene
Gene (GenBank)vcaC
EC number2.1.1.-
Keyword
  • L-vancosamine
Note
Note (GenBank)
Reference
ACC
Related Reference
ACC
R4SV93
PmId
[24884615] Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis. (BMC Genomics. , 2014)
ACC
P96561
NITE
Chlor_00150
PmId
[11035791] Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. (Proc Natl Acad Sci U S A. , 2000)

close this sectionSequence

selected fasta
>putative dTDP-3-amino-4-keto-2,3,6-trideoxy-D-glucose C-3 C-methyltransferase [putative C-3 methyltransferase]
MSTTSQCRICDGTVTEFIDFGRQPLSDAFVVPGDEKKEFFFRLATGICESCTMVQLMEEV
PRDLMFHEAYPYHSSGSAVMRTHFHDLAKRFLTTELTGEDPFIVELGCNDGIMLKAIAEA
GVRQLGVEPSGGVADLAAAKGIRVRKDFFEEATAADIRKNDGPADVIYAANTLCHIPYMD
SILKGVTTLLGPNGVFVFEDPYLGDIVERTSFDQIYDEHFFFFTARSVQEMARRNGLELV
DVERIPVHGGEVRYTLALAGARKPTEAVAELLAWEAERKLSEFATLERFAANVKKVKEDL
IALLTKLRAEGKRVVGYGATAKSATVTNFCGITPDLVEFISDTTPAKQGKLSPGQHIPVR
EYREFADDHPDYALLFAWNHADEIMNAEQAFRDAGGQWIRYVPNVHVS
selected fasta
>putative dTDP-3-amino-4-keto-2,3,6-trideoxy-D-glucose C-3 C-methyltransferase [putative C-3 methyltransferase]
ATGTCGACCACGTCCCAGTGCCGTATCTGTGACGGCACCGTCACCGAGTTCATCGACTTC
GGACGTCAGCCGCTTTCGGACGCGTTCGTGGTTCCCGGTGACGAGAAGAAGGAGTTCTTC
TTCCGGCTCGCCACCGGGATCTGCGAGTCCTGCACGATGGTGCAGCTGATGGAAGAGGTC
CCGCGGGACCTGATGTTCCACGAGGCATACCCCTACCACTCGTCCGGTTCGGCCGTCATG
CGCACGCATTTCCACGATCTGGCCAAACGCTTCCTGACCACGGAGCTGACCGGCGAGGAC
CCGTTCATCGTCGAACTCGGCTGCAACGACGGCATCATGCTCAAGGCCATCGCGGAGGCG
GGAGTGCGCCAGCTCGGCGTCGAACCCTCCGGCGGTGTCGCGGATCTGGCCGCGGCCAAG
GGAATCCGCGTCCGCAAGGACTTCTTCGAAGAGGCGACGGCGGCCGACATCCGGAAGAAC
GACGGCCCCGCCGACGTGATCTACGCGGCCAACACCCTGTGCCACATCCCTTACATGGAC
TCGATCCTCAAGGGCGTCACCACCTTGCTGGGCCCGAACGGCGTGTTCGTGTTCGAGGAC
CCGTACCTCGGTGACATCGTCGAGCGCACGTCGTTCGACCAGATCTACGACGAGCATTTC
TTCTTCTTCACCGCGCGCTCGGTGCAGGAGATGGCCCGGCGCAACGGGCTCGAACTCGTG
GACGTCGAGCGCATCCCGGTGCACGGCGGCGAGGTCCGCTACACCCTCGCCCTCGCCGGG
GCCCGCAAGCCGACCGAGGCCGTGGCGGAACTCCTGGCGTGGGAGGCGGAGCGCAAGCTG
TCCGAGTTCGCCACGCTGGAACGCTTCGCCGCCAACGTGAAGAAGGTCAAGGAAGACCTC
ATCGCGCTGCTGACCAAGCTCCGCGCCGAGGGCAAACGCGTCGTCGGCTACGGCGCGACG
GCCAAGAGCGCCACGGTGACCAACTTCTGTGGCATCACCCCGGATCTGGTCGAGTTCATC
TCGGACACCACTCCCGCCAAACAGGGCAAGCTCAGCCCGGGGCAGCACATCCCGGTCCGC
GAGTACCGGGAGTTCGCCGACGATCACCCCGACTACGCGCTGCTGTTCGCCTGGAACCAC
GCCGACGAGATCATGAACGCGGAGCAGGCTTTCCGTGACGCCGGTGGGCAGTGGATCCGG
TACGTGCCGAACGTGCACGTGAGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR013630 Methyltransferase putative zinc binding domain (Domain)
 [7-67]  1.69999999999999e-20 PF08421
PF08421   Methyltransf_13
IPR013691 C-methyltransferase (Domain)
 [245-403]  2.89999999999999e-56 PF08484
PF08484   Methyltransf_14
SignalP No significant hit
TMHMM No significant hit