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CDS information : Vanco_00300


close this sectionLocation

Organism
StrainATCC 19795 (=NBRC 12806)
Entry nameVancomycin
Contig
Start / Stop / Direction60,314 / 61,423 / + [in whole cluster]
60,314 / 61,423 / + [in contig]
Location60314..61423 [in whole cluster]
60314..61423 [in contig]
TypeCDS
Length1,110 bp (369 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category2.3 modification addition of sugar moiety
Productputative dTDP-hexose C-3 aminotransferase
Product (GenBank)putative C-3 aminotransferase
Gene
Gene (GenBank)vcaB
EC number2.6.1.-
Keyword
  • L-vancosamine
Note
Note (GenBank)
Reference
ACC
Related Reference
ACC
R4T063
PmId
[24884615] Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis. (BMC Genomics. , 2014)
ACC
O52807
NITE
Chlor_00260
PmId
[11035791] Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. (Proc Natl Acad Sci U S A. , 2000)

close this sectionSequence

selected fasta
>putative dTDP-hexose C-3 aminotransferase [putative C-3 aminotransferase]
MTTRVWDYLAEYEAERLDLLDAVETVFNSGQLVLGASLRGFEAEFAAYHGVGHCVGLDNG
TNAIKLGLQALGVGPGDEVITVSNTAAPTVVAIDGTGATPVFVDVREDDFLMDTTQVEAA
ITERTKCLLPVHLYGQCVDLAPLKELAAKHGLSLLEDCAQAHGARQNGTVAGSTGDAAAF
SFYPTKVLGAYGDGGATITSDEAVERKLRRLRYYGMEERYYTVETPAHNSRLDEVQAEIL
RRKLKRLDAYVDGRRAVARRYEEGLGDTELKLPKTTPGNEHVYYVYVVRHPRRDEILERL
KAYDIHLNISYPWPVHTMTGFAHLGYGTGSLPVTEKLAGEIFSLPMYPALSTDLQDKVVH
AVREVLSAL
selected fasta
>putative dTDP-hexose C-3 aminotransferase [putative C-3 aminotransferase]
ATGACCACGCGTGTATGGGACTACCTGGCCGAATACGAGGCCGAGCGGCTCGACCTGCTC
GACGCGGTCGAGACGGTCTTCAACTCGGGCCAGCTCGTTCTCGGCGCGAGCCTGCGCGGC
TTCGAAGCGGAGTTCGCCGCCTATCACGGGGTCGGTCACTGTGTCGGCCTCGACAACGGC
ACGAACGCGATCAAGCTCGGCCTGCAGGCCCTCGGGGTCGGACCGGGCGACGAGGTGATC
ACGGTGTCGAACACCGCCGCCCCGACCGTGGTCGCCATCGACGGCACCGGCGCCACCCCG
GTCTTCGTCGACGTCCGCGAGGACGACTTCCTGATGGACACCACACAGGTCGAGGCCGCG
ATCACCGAGCGGACCAAATGCCTGCTGCCCGTGCACCTGTACGGCCAGTGCGTGGACCTG
GCCCCGCTGAAGGAACTCGCCGCGAAGCACGGACTGTCCCTTTTGGAGGATTGCGCCCAG
GCACACGGGGCCCGGCAGAACGGGACGGTCGCCGGTTCGACCGGTGACGCGGCCGCGTTC
TCCTTCTATCCCACCAAGGTGCTCGGCGCCTACGGCGACGGCGGCGCGACCATCACGTCC
GACGAAGCCGTGGAGCGCAAGCTGCGGAGGCTGCGGTACTACGGCATGGAAGAGCGTTAC
TACACGGTGGAAACGCCCGCCCACAACAGCCGTCTCGACGAGGTCCAGGCCGAGATCCTG
CGGCGCAAGCTCAAGCGGCTCGACGCCTACGTCGACGGACGCCGTGCCGTCGCCCGGCGC
TACGAAGAAGGCCTCGGCGACACCGAGCTGAAACTGCCGAAGACCACCCCCGGCAACGAG
CACGTGTACTACGTGTACGTGGTACGCCACCCGCGGCGCGACGAGATCCTCGAACGCCTC
AAGGCGTACGACATCCACCTGAACATCAGCTATCCGTGGCCGGTGCACACCATGACCGGG
TTCGCCCACCTCGGCTACGGCACGGGTTCGCTGCCGGTCACCGAGAAGCTGGCGGGCGAG
ATCTTCTCGCTCCCGATGTATCCCGCGCTTTCCACCGATCTGCAGGACAAGGTCGTCCAC
GCGGTCCGCGAAGTGCTGTCCGCCCTCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase (Family)
 [1-368]  2.89997807423186e-89 PIRSF000390
PIRSF000390   PLP_StrS
 [18-363]  2.50000000000001e-115 PF01041
PF01041   DegT_DnrJ_EryC1
IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (Domain)
 [19-246]  6.7999999999999e-75 G3DSA:3.40.640.10
G3DSA:3.40.640.10   PyrdxlP-dep_Trfase_major_sub1
IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (Domain)
 [247-367]  1.2e-37 G3DSA:3.90.1150.10
G3DSA:3.90.1150.10   PyrdxlP-dep_Trfase_major_sub2
IPR015424 Pyridoxal phosphate-dependent transferase, major domain (Domain)
 [16-369]  3.49999466863949e-101 SSF53383
SSF53383   PyrdxlP-dep_Trfase_major
SignalP No significant hit
TMHMM No significant hit