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CDS information : Virg_00350


close this sectionLocation

Organism
StrainMAFF 10-06014
Entry nameVirginiamycin
Contig
Start / Stop / Direction103,614 / 104,264 / + [in whole cluster]
373 / 1,023 / + [in contig]
Location103614..104264 [in whole cluster]
373..1023 [in contig]
TypeCDS
Length651 bp (216 aa)
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close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative TetR family transcriptional regulator
Product (GenBank)BarB
Gene
Gene (GenBank)barB
EC number
Keyword
Note
  • This ORF is involved in both virginiamycin M and virginiamycin S biosynthesis.
Note (GenBank)
Reference
ACC
PmId
[14647980] Identification by gene deletion analysis of barB as a negative regulator controlling an early process of virginiamycin biosynthesis in Streptomyces virginiae. (Arch Microbiol. , 2004)

close this sectionSequence

selected fasta
>putative TetR family transcriptional regulator [BarB]
MTPKQERAFRTRTQLVLSAAEAFDRQGFATASLTAISNSAGVSNGALHFHFESKEALAAA
VEAEAAERMRTIVDGAARRGASALQALVDTSHAVMLRLRQDVVVRAGFRLSGDAARQATH
DLPEHWRQSVVRLLERAGRDGSLTSAVTPSDVAGVVTATVLGFGVLARFDSAWLASGSLS
GFWKLMLPMIAAGPVERGELDCRPAVPADVRRAPAV
selected fasta
>putative TetR family transcriptional regulator [BarB]
TTGACACCCAAACAGGAACGCGCCTTCCGCACCCGCACCCAGCTGGTGCTCTCGGCGGCC
GAGGCCTTCGATCGGCAGGGTTTCGCGACGGCCTCGCTCACCGCCATCAGCAACAGCGCC
GGTGTCAGTAACGGGGCCCTGCACTTCCACTTCGAGAGCAAGGAAGCGCTCGCCGCCGCC
GTCGAAGCGGAGGCGGCCGAGCGGATGCGGACGATCGTCGACGGAGCGGCCCGGAGGGGC
GCTTCCGCGCTCCAGGCCCTGGTCGACACCAGTCACGCCGTCATGCTCCGGCTGCGCCAG
GACGTGGTGGTGCGCGCCGGGTTCCGGCTCAGCGGCGATGCGGCCCGACAGGCCACCCAC
GACCTCCCGGAGCACTGGCGCCAGAGTGTCGTGCGGCTGCTGGAGCGGGCCGGCCGGGAC
GGCTCGCTGACCTCGGCCGTGACGCCCTCGGACGTCGCCGGGGTCGTGACGGCCACCGTC
CTCGGATTCGGCGTGCTGGCGAGGTTCGACTCCGCCTGGCTGGCCTCCGGATCCCTCTCC
GGGTTCTGGAAGCTGATGCTCCCCATGATCGCGGCCGGTCCGGTCGAGCGCGGCGAACTG
GACTGCCGGCCCGCCGTGCCGGCCGACGTCCGGCGCGCGCCCGCCGTCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09
show BLAST table
InterPro
Database:interpro:38.0
IPR001647 DNA-binding HTH domain, TetR-type (Domain)
 [15-28]  6.80000200614765e-08 PR00455 [36-59]  6.80000200614765e-08 PR00455
PR00455   HTHTETR
 [17-61]  1.4e-12 PF00440
PF00440   TetR_N
 [9-69]  PS50977
PS50977   HTH_TETR_2
IPR009057 Homeodomain-like (Domain)
 [1-87]  2.2999993566538e-15 SSF46689
SSF46689   Homeodomain_like
IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal (Domain)
 [81-194]  1.89999859865865e-21 SSF48498
SSF48498   TetR_like_C
IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal (Domain)
 [10-194]  9e-37 G3DSA:1.10.357.10
G3DSA:1.10.357.10   TetR_C
IPR023772 DNA-binding HTH domain, TetR-type, conserved site (Conserved_site)
 [27-57]  PS01081
PS01081   HTH_TETR_1
SignalP No significant hit
TMHMM No significant hit