遺伝子 : Serine/alanine racemase (VANTG)

遺伝子情報

ID	NRULE_0272
遺伝子ID	VANTG
作成日	2014/07/04
タンパク質名	Protein name Full Serine/alanine racemase EC EC 5.1.1.-
遺伝子名	vanTG
遺伝子条件	HAMAP; MF_01201; hit=1ANDBLASTP; Q6WRY3; hit=1; score=2900; pid=78
参照	Gene Ontology GO GO:0016021, C:integral component of membrane, IEA:InterPro GO:0008784, F:alanine racemase activity, IEA:InterPro GO:0030170, F:pyridoxal phosphate binding, IEA:InterPro GO:0016747, F:transferase activity, transferring acyl groups other than amino-acyl groups, IEA:InterPro GO:0006522, P:alanine metabolic process, IEA:InterPro GO:0046677, P:response to antibiotic, IEA:InterPro Family and domain databases HAMAP MF_01201, Ala_racemase, 1 InterPro IPR002656, Acyl_transf_3 IPR000821, Ala_racemase IPR009006, Ala_racemase/Decarboxylase_C IPR011079, Ala_racemase_C IPR001608, Ala_racemase_N IPR020622, Ala_racemase_pyridoxalP-BS IPR029066, PLP-binding_barrel IPR011248, Serine/alanine_racemase Pfam PF01757, Acyl_transf_3, 1 PF00842, Ala_racemase_C, 1 PF01168, Ala_racemase_N, 1 PIRSF PIRSF036464, Ser_ala_racem, 1 PRINTS PR00992, ALARACEMASE SMART SM01005, Ala_racemase_C, 1 TIGRFAMs TIGR00492, alr, 1 PROSITE PS00395, ALANINE_RACEMASE, 1
配列の特徴	Q6WRY3 Enterococcus faecalis (Streptococcus faecalis). BINDING 380 Sulfate. BINDING 463 Chloride 1. BINDING 471 Chloride 1; via amide nitrogen. BINDING 541 Chloride 2; via amide nitrogen. BINDING 542 Sulfate. BINDING 654 Chloride 1.
注釈	Catalytic activity L-alanine = D-alanine Cofactor Pyridoxal phosphate (By similarity)
参考文献	Q6WRY3 Enterococcus faecalis (Streptococcus faecalis). 14617152 The vanG glycopeptide resistance operon from Enterococcus faecalis revisited. (Mol Microbiol. 2003)

関与する機能

機能名
Vancomycin resistance (via D-Ala-D-Ser precursor)

該当CDS