Alanine racemization(NFUNC_0063) |
必須 | A | ALR (NRULE_0228) | Alanine racemase | ECL_01514 ECL_00311 |
Anthranilate biosynthesis(NFUNC_0038) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | ECL_04737 ECL_01728 |
TRPE (NRULE_0143) | Anthranilate synthase component I | ECL_01729 |
Aromatic azo compounds degradation(NFUNC_0073) |
必須 | A | AZOR (NRULE_0236) | FMN-dependent NADH-azoreductase | ECL_02091 |
Arsenical resistance(NFUNC_0004) |
必須 | A | ARSB1 (NRULE_0015) | Arsenical pump membrane protein | ECL_00466 ECL_02870 ECL_A099 |
ARSC1 (NRULE_0017) | Arsenate reductase | ECL_00465 ECL_02871 ECL_03781 ECL_A100 |
B | ARSB1 (NRULE_0015) | Arsenical pump membrane protein | ECL_00466 ECL_02870 ECL_A099 |
ARSC2 (NRULE_0018) | Arsenate reductase | ECL_00469 ECL_00464 ECL_03833 |
D | ARSB2 (NRULE_0016) | Arsenite resistance protein ArsB | ECL_03834 |
ARSC1 (NRULE_0017) | Arsenate reductase | ECL_A100 ECL_00465 ECL_02871 ECL_03781 |
E | ARSB2 (NRULE_0016) | Arsenite resistance protein ArsB | ECL_03834 |
ARSC2 (NRULE_0018) | Arsenate reductase | ECL_00464 ECL_03833 ECL_00469 |
任意 | | ARSA (NRULE_0014) | Arsenical pump-driving ATPase | ECL_A098 ECL_A102 ECL_00467 |
| ARSD (NRULE_0020) | Arsenical resistance operon trans-acting repressor ArsD | ECL_00468 ECL_A103 ECL_A097 |
| ARSH (NRULE_0021) | ArsH protein | ECL_03832 ECL_A105 ECL_00459 |
Bacitracin resistance(NFUNC_0022) |
必須 | A | UPPP (NRULE_0097) | Undecaprenyl-diphosphatase | ECL_04383 |
Beta-lactam antibiotic resistance(NFUNC_0033) |
必須 | C | BLAC (NRULE_0124) | Beta-lactamase class C | ECL_00553 |
Betaine biosynthesis (from choline)(NFUNC_0049) |
必須 | A | BETA (NRULE_0175) | Choline dehydrogenase | ECL_03123 |
Biotin biosynthesis(NFUNC_0051) |
必須 | A | BIOF (NRULE_0182) | 8-amino-7-oxononanoate synthase | ECL_02960 |
BIOA (NRULE_0183) | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | ECL_02962 |
BIOD (NRULE_0184) | ATP-dependent dethiobiotin synthetase BioD | ECL_02958 ECL_02219 |
BIOB (NRULE_0185) | Biotin synthase | ECL_02961 |
Cephalosporin resistance(NFUNC_0048) |
必須 | A | BLAC (NRULE_0124) | Beta-lactamase class C | ECL_00553 |
Folate biosynthesis(NFUNC_0044) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | ECL_01728 ECL_04737 |
DHPS (NRULE_0144) | Dihydropteroate synthase | ECL_03814 ECL_04556 |
FOLM (NRULE_0146) | Dihydrofolate reductase FolM | ECL_02267 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | ECL_03652 ECL_04384 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | ECL_00946 |
FOLC (NRULE_0160) | Bifunctional protein FolC | ECL_03664 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | ECL_01492 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | ECL_02540 |
B | GLAT (NRULE_0142) | Glutamine amidotransferase | ECL_01728 ECL_04737 |
DHPS (NRULE_0144) | Dihydropteroate synthase | ECL_04556 ECL_03814 |
FOLA (NRULE_0147) | Dihydrofolate reductase | ECL_00846 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | ECL_03652 ECL_04384 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | ECL_00946 |
FOLC (NRULE_0160) | Bifunctional protein FolC | ECL_03664 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | ECL_01492 |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | ECL_02540 |
Fosfomycin resistance(NFUNC_0023) |
必須 | A | FOSA (NRULE_0098) | Glutathione transferase FosA | ECL_00705 |
Macrolide antibiotic resistance(NFUNC_0045) |
必須 | B | RLMA (NRULE_0165) | 23S rRNA (guanine-N(1))-methyltransferase | ECL_01482 |
C | MACA (NRULE_0166) | Macrolide-specific efflux protein MacA | ECL_02771 |
MACB (NRULE_0167) | Macrolide export ATP-binding/permease protein MacB | ECL_00381 ECL_02770 |
Mercury resistance(NFUNC_0005) |
必須 | A | MERA (NRULE_0008) | Mercuric reductase | ECL_A232 ECL_03824 ECL_A045 |
Metal-binding protein(NFUNC_0105) |
必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | ECL_02976 ECL_02972 ECL_02648 ECL_04172 |
B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | ECL_02976 |
C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | ECL_05060 ECL_02974 ECL_03176 ECL_03257 ECL_01119 ECL_03753 |
E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | ECL_01254 |
F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | ECL_00321 |
G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR | ECL_04669 |
I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | ECL_03880 |
Molybdate transport (ABC transporter)(NFUNC_0097) |
必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | ECL_03176 ECL_05060 ECL_03753 ECL_03257 ECL_02974 ECL_01119 |
任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | ECL_02976 |
| MODB (NRULE_0325) | Molybdate ABC transporter permease protein | ECL_02973 |
| MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | ECL_02972 |
(R)-pantothenate biosynthesis(NFUNC_0030) |
必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | ECL_00943 |
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | ECL_00945 |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | ECL_03147 ECL_01182 |
PANC (NRULE_0118) | Pantothenate synthetase | ECL_00944 |
Phenol degradation(NFUNC_0028) |
必須 | B | PHEA1 (NRULE_0083) | Aromatic ring hydroxylase | ECL_00750 |
任意 | | FDR1 (NRULE_0032) | Oxygenase electron transfer component | ECL_02779 ECL_01062 ECL_02149 |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | ECL_02669 ECL_04264 ECL_04266 |
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | ECL_02627 ECL_03076 ECL_01887 ECL_00749 |
Polymyxin resistance(NFUNC_0036) |
必須 | A | ARNA (NRULE_0132) | Bifunctional polymyxin resistance protein ArnA | ECL_04861 |
ARNB (NRULE_0133) | UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase | ECL_04863 |
ARNC (NRULE_0134) | Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase | ECL_04862 |
ARND (NRULE_0135) | Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | ECL_04860 |
ARNE (NRULE_0136) | Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE | ECL_04858 |
ARNF (NRULE_0137) | Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF | ECL_04857 |
ARNT (NRULE_0138) | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | ECL_04859 |
Riboflavin biosynthesis(NFUNC_0058) |
必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | ECL_04376 |
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | ECL_01744 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | ECL_01172 |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | ECL_01173 |
RIBE (NRULE_0204) | Riboflavin synthase | ECL_02345 |
任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | ECL_00833 |
Trehalose biosynthesis (from maltooligosaccharide)(NFUNC_0037) |
必須 | A | TREY (NRULE_0140) | Maltooligosyl trehalose synthase | ECL_01950 |
TREZ (NRULE_0141) | Malto-oligosyltrehalose trehalohydrolase | ECL_01949 |
任意 | | GLGX (NRULE_0139) | Glycogen debranching enzyme | ECL_01951 ECL_04793 |
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031) |
必須 | A | TPS (NRULE_0119) | Trehalose-phosphate synthase | ECL_01398 |
TPP (NRULE_0120) | Trehalose-6-phosphate phosphatase | ECL_01397 |
Uptake of osmoprotectant(NFUNC_0061) |
必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | ECL_04019 |
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | ECL_04018 |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | ECL_04017 ECL_02216 |
C | BCCT (NRULE_0220) | BCCT family transporter | ECL_02496 ECL_03120 |
D | PROP (NRULE_0221) | Osmoprotectant transporter | ECL_00368 |
E | OPUE (NRULE_0222) | Sodium/proline symporter | ECL_02618 |
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) |
必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase | ECL_04247 |
PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase | ECL_03669 |
SERC (NRULE_0210) | Phosphoserine aminotransferase | ECL_02746 |
PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | ECL_01996 ECL_00850 |
PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | ECL_03902 |