Alanine racemization(NFUNC_0063) |
| 必須 | A | ALR (NRULE_0228) | Alanine racemase | EY7_389_00060 |
|---|
Artificial lacto-N-biose biosynthesis(NFUNC_0026) |
| 必須 | A | SP (NRULE_0109) | Sucrose phosphorylase | EY7_356_00020 |
|---|
GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | |
GALE (NRULE_0111) | UDP-glucose 4-epimerase | EY7_421_00010 EY7_801_00030 |
LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase | |
Chlorocatechol degradation (beta-ketoadipate pathway)(NFUNC_0104) |
| 必須 | A | PCAI (NRULE_0072) | 3-oxoadipate CoA-transferase subunit A | |
|---|
PCAJ (NRULE_0073) | 3-oxoadipate CoA-transferase subunit B | |
PCAF (NRULE_0074) | Beta-ketoadipyl-CoA thiolase | |
CLCA (NRULE_0382) | Chlorocatechol 1,2-dioxygenase | |
CLCD (NRULE_0383) | Dienelactone hydrolase | EY7_166_00010 |
CLCE (NRULE_0384) | Maleylacetate reductase | |
CLCB (NRULE_0387) | Chloromuconate cycloisomerase | |
| B | CATB2 (NRULE_0053) | (Chloro)muconate cycloisomerase | |
PCAI (NRULE_0072) | 3-oxoadipate CoA-transferase subunit A | |
PCAJ (NRULE_0073) | 3-oxoadipate CoA-transferase subunit B | |
PCAF (NRULE_0074) | Beta-ketoadipyl-CoA thiolase | |
CLCA (NRULE_0382) | Chlorocatechol 1,2-dioxygenase | |
CLCD (NRULE_0383) | Dienelactone hydrolase | EY7_166_00010 |
CLCE (NRULE_0384) | Maleylacetate reductase | |
| 任意 | | CLCF (NRULE_0385) | Chloromuconolactone dehalogenase | |
|---|
Dihydroxy aromatic compounds degradation (via meta-cleavage pathway)(NFUNC_0011) |
| 必須 | A | EDIO (NRULE_0058) | extradiol dioxygenase | EY7_143_00010 |
|---|
METAH (NRULE_0059) | meta-cleavage compound hydrolase | |
HPDH (NRULE_0063) | 2-hydroxypent-2,4-dienoate hydratase | |
HOA (NRULE_0064) | 4-hydroxy-2-oxovalerate aldolase | |
ACDH (NRULE_0065) | Acetaldehyde dehydrogenase | |
| B | EDIO (NRULE_0058) | extradiol dioxygenase | EY7_143_00010 |
2HMSD (NRULE_0060) | 2-hydroxymuconic semialdehyde dehydrogenase | |
4OT (NRULE_0061) | 4-oxalocrotonate tautomerase | EY7_1048_00020 |
4OD (NRULE_0062) | 4-oxalocrotonate decarboxylase | |
HPDH (NRULE_0063) | 2-hydroxypent-2,4-dienoate hydratase | |
HOA (NRULE_0064) | 4-hydroxy-2-oxovalerate aldolase | |
ACDH (NRULE_0065) | Acetaldehyde dehydrogenase | |
Folate biosynthesis(NFUNC_0044) |
| 必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | |
|---|
DHPS (NRULE_0144) | Dihydropteroate synthase | |
FOLM (NRULE_0146) | Dihydrofolate reductase FolM | |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | EY7_1058_00040 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | EY7_1058_00030 |
FOLC (NRULE_0160) | Bifunctional protein FolC | EY7_711_00010 EY7_705_00010 EY7_330_00010 EY7_1058_00010 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
| B | GLAT (NRULE_0142) | Glutamine amidotransferase | |
DHPS (NRULE_0144) | Dihydropteroate synthase | |
FOLA (NRULE_0147) | Dihydrofolate reductase | EY7_569_00020 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | EY7_1058_00040 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | EY7_1058_00030 |
FOLC (NRULE_0160) | Bifunctional protein FolC | EY7_711_00010 EY7_705_00010 EY7_330_00010 EY7_1058_00010 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
| C | GLAT (NRULE_0142) | Glutamine amidotransferase | |
DHPS (NRULE_0144) | Dihydropteroate synthase | |
DFR2 (NRULE_0148) | Dihydrofolate reductase type 2 | |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | EY7_1058_00040 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | EY7_1058_00030 |
FOLC (NRULE_0160) | Bifunctional protein FolC | EY7_705_00010 EY7_1058_00010 EY7_711_00010 EY7_330_00010 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
Human milk oligosaccharides metabolism(NFUNC_0083) |
| 必須 | A | LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase | |
|---|
| 任意 | | NAHK (NRULE_0256) | N-acetylhexosamine 1-kinase | |
|---|
| | GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | |
| | GALE (NRULE_0111) | UDP-glucose 4-epimerase | EY7_421_00010 EY7_801_00030 |
Metal-binding protein(NFUNC_0105) |
| 必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | |
|---|
| B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | |
| C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | EY7_413_00010 |
| D | MNTR (NRULE_0327) | DtxR family transcriptional regulator MntR | |
| E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | |
| F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | |
| G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR | |
| H | NIKR (NRULE_0331) | Nickel-responsive transcriptional regulator NikR | |
| I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | |
| J | SMTA (NRULE_0009) | Metallothionein | |
Molybdate transport (ABC transporter)(NFUNC_0097) |
| 必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | EY7_413_00010 |
|---|
| 任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | |
|---|
| | MODB (NRULE_0325) | Molybdate ABC transporter permease protein | |
| | MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | |
Naphthalene degradation (via hydroxylation by dioxygenase)(NFUNC_0067) |
| 必須 | A | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit | |
|---|
RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit | |
CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase | |
EDIO (NRULE_0058) | extradiol dioxygenase | EY7_143_00010 |
NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase | |
NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | |
NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase | |
NAHG (NRULE_0190) | Salicylate hydroxylase | |
| B | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit | |
RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit | |
CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase | |
EDIO (NRULE_0058) | extradiol dioxygenase | EY7_143_00010 |
NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase | |
NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | |
NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase | |
NAGG (NRULE_0191) | Salicylate 5-hydroxylase alpha subunit | |
NAGH (NRULE_0192) | Salicylate 5-hydroxylase beta subunit | |
| 任意 | | FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
|---|
| | FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | |
| | FDR2 (NRULE_0057) | Ferredoxin reductase | |
(R)-pantothenate biosynthesis(NFUNC_0030) |
| 必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | |
|---|
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | EY7_283_00030 EY7_956_00010 EY7_429_00010 |
PANC (NRULE_0118) | Pantothenate synthetase | |
Riboflavin biosynthesis(NFUNC_0058) |
| 必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | EY7_758_00050 |
|---|
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | EY7_758_00060 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | EY7_758_00070 |
RIBE (NRULE_0204) | Riboflavin synthase | EY7_758_00040 |
| 任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | EY7_813_00090 |
|---|
Trehalose biosynthesis (from maltose)(NFUNC_0034) |
| 必須 | A | MAPA (NRULE_0126) | Maltose phosphorylase | EY7_785_00010 |
|---|
TREP (NRULE_0127) | Alpha,alpha-trehalose phosphorylase | |
| B | TRES (NRULE_0128) | Trehalose synthase | |
Uptake of osmoprotectant(NFUNC_0061) |
| 必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | |
|---|
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | EY7_729_00030 |
| B | EHUB (NRULE_0216) | Ectoine ABC transporter substrate-binding protein | |
EHUC (NRULE_0217) | Ectoine ABC transporter permease protein | |
EHUD (NRULE_0218) | Ectoine ABC transporter permease protein | |
EHUA (NRULE_0219) | Ectoine ABC transporter ATP-binding protein | |
| C | BCCT (NRULE_0220) | BCCT family transporter | |
| D | PROP (NRULE_0221) | Osmoprotectant transporter | |
| E | OPUE (NRULE_0222) | Sodium/proline symporter | |
| F | TEAA (NRULE_0223) | TRAP transporter substrate-binding protein TeaA | |
TEAB (NRULE_0224) | TRAP transporter small transmembrane protein TeaB | |
TEAC (NRULE_0225) | TRAP transporter large transmembrane protein TeaC | |
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060) |
| 必須 | A | EPD (NRULE_0208) | D-erythrose-4-phosphate dehydrogenase | |
|---|
PDXB (NRULE_0209) | Erythronate-4-phosphate dehydrogenase | |
SERC (NRULE_0210) | Phosphoserine aminotransferase | EY7_163_00010 |
PDXA (NRULE_0211) | 4-hydroxythreonine-4-phosphate dehydrogenase | |
PDXJ (NRULE_0212) | Pyridoxine 5'-phosphate synthase | |
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059) |
| 必須 | A | PDXS (NRULE_0206) | Pyridoxal biosynthesis lyase PdxS | |
|---|
PDXT (NRULE_0207) | Glutamine amidotransferase subunit PdxT | EY7_342_00010 EY7_958_00020 |
