Alanine racemization(NFUNC_0063) |
必須 | A | ALR (NRULE_0228) | Alanine racemase | Xcel_0673 |
n-alkane hydroxylation(NFUNC_0008) |
必須 | A | CYP153 (NRULE_0041) | Cytochrome P450 CYP153 | |
B | ALKB (NRULE_0024) | Alkane 1-monooxygenase | |
C | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit | |
MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit | |
FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
MME (NRULE_0033) | Multicomponent monooxygenase effector protein | |
任意 | | RUBA (NRULE_0039) | Rubredoxin | |
| RUBB (NRULE_0040) | Rubredoxin reductase | |
| MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit | |
| MMG2 (NRULE_0030) | Multicomponent monooxygenase gamma subunit | |
| MMG3 (NRULE_0031) | Multicomponent monooxygenase gamma subunit | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_1306 Xcel_1359 Xcel_2010 Xcel_2768 |
D-allose biosynthesis(NFUNC_0077) |
必須 | A | LRHI (NRULE_0242) | L-rhamnose isomerase | Xcel_0886 |
Aminoglycoside resistance (by aminoglycoside N-acetyltransferase)(NFUNC_0041) |
必須 | A | AAC3 (NRULE_0149) | Aminoglycoside N(3')-acetyltransferase | Xcel_0724 |
B | AAC6 (NRULE_0150) | Aminoglycoside N(6')-acetyltransferase | |
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043) |
必須 | A | APH6 (NRULE_0155) | Streptomycin 6-kinase | Xcel_0261 |
B | APH3 (NRULE_0156) | Aminoglycoside 3'-phosphotransferase | |
C | APH7 (NRULE_0157) | Hygromycin-B 7''-O-kinase | |
D | HPH (NRULE_0174) | Hygromycin-B 4-O-kinase | |
Ampicillin resistance(NFUNC_0046) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | |
任意 | | BLAB (NRULE_0123) | Metallo-beta-lactamase | |
| BLAD (NRULE_0125) | Beta-lactamase class D | Xcel_3275 |
Aniline degradation (conversion into catechol)(NFUNC_0075) |
必須 | A | ATDA1 (NRULE_0240) | Gamma-glutamylanilide synthetase | |
ATDA3 (NRULE_0357) | Aniline dioxygenase large subunit | |
ATDA4 (NRULE_0358) | Aniline dioxygenase small subunit | |
任意 | | ATDA2 (NRULE_0241) | Putative gamma-glutamylanilide hydrolase | |
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_2768 Xcel_1359 Xcel_1306 Xcel_2010 |
| FDR2 (NRULE_0057) | Ferredoxin reductase | |
Anthranilate biosynthesis(NFUNC_0038) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | Xcel_0017 |
TRPE (NRULE_0143) | Anthranilate synthase component I | |
Anthranilate degradation (via hydroxylation)(NFUNC_0018) |
必須 | A | ANTA (NRULE_0044) | Anthranilate 1,2-dioxygenase large subunit | |
ANTB (NRULE_0045) | Anthranilate 1,2-dioxygenase small subunit | |
任意 | | ANTC (NRULE_0081) | Anthranilate 1,2-dioxygenase electron transfer component | |
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_1359 Xcel_1306 Xcel_2010 Xcel_2768 |
| FDR2 (NRULE_0057) | Ferredoxin reductase | |
Aromatic hydrocarbon degradation (via hydroxylation by dioxygenase)(NFUNC_0016) |
必須 | A | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit | |
RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit | |
CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase | |
任意 | | FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_1359 Xcel_1306 Xcel_2010 Xcel_2768 |
| FDR2 (NRULE_0057) | Ferredoxin reductase | |
Artificial lacto-N-biose biosynthesis(NFUNC_0026) |
必須 | A | SP (NRULE_0109) | Sucrose phosphorylase | |
GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | |
GALE (NRULE_0111) | UDP-glucose 4-epimerase | Xcel_3082 |
LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase | |
Bacitracin resistance(NFUNC_0022) |
必須 | A | UPPP (NRULE_0097) | Undecaprenyl-diphosphatase | Xcel_1478 |
Benzoate degradation (via hydroxylation by dioxygenase)(NFUNC_0017) |
必須 | A | BENA (NRULE_0046) | Benzoate 1,2-dioxygenase alpha subunit | |
BENB (NRULE_0047) | Benzoate 1,2-dioxygenase beta subunit | |
BEND (NRULE_0082) | 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase | |
任意 | | BENC (NRULE_0055) | Benzoate 1,2-dioxygenase electron transfer component | |
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_1359 Xcel_2768 Xcel_2010 Xcel_1306 |
| FDR2 (NRULE_0057) | Ferredoxin reductase | |
Beta-lactam antibiotic resistance(NFUNC_0033) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | |
B | BLAB (NRULE_0123) | Metallo-beta-lactamase | |
C | BLAC (NRULE_0124) | Beta-lactamase class C | |
D | BLAD (NRULE_0125) | Beta-lactamase class D | Xcel_3275 |
Chloramphenicol resistance(NFUNC_0025) |
必須 | A | CAT1 (NRULE_0107) | Chloramphenicol acetyltransferase | Xcel_3311 |
B | CAT4 (NRULE_0108) | Chloramphenicol acetyltransferase | |
Dibenzothiophene degradation (via desulfurization)(NFUNC_0029) |
必須 | A | DSZA (NRULE_0103) | Dibenzothiophene-5,5-dioxide monooxygenase | |
DSZB (NRULE_0104) | 2'-hydroxybiphenyl-2-sulfinate desulfinase | |
DSZC (NRULE_0105) | Dibenzothiophene monooxygenase | |
任意 | | FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_1979 Xcel_0311 |
Folate biosynthesis(NFUNC_0044) |
必須 | A | GLAT (NRULE_0142) | Glutamine amidotransferase | Xcel_0017 |
DHPS (NRULE_0144) | Dihydropteroate synthase | Xcel_0978 Xcel_2985 |
FOLM (NRULE_0146) | Dihydrofolate reductase FolM | |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | Xcel_2984 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | Xcel_2984 |
FOLC (NRULE_0160) | Bifunctional protein FolC | Xcel_1149 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
B | GLAT (NRULE_0142) | Glutamine amidotransferase | Xcel_0017 |
DHPS (NRULE_0144) | Dihydropteroate synthase | Xcel_2985 Xcel_0978 |
FOLA (NRULE_0147) | Dihydrofolate reductase | Xcel_2833 |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | Xcel_2984 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | Xcel_2984 |
FOLC (NRULE_0160) | Bifunctional protein FolC | Xcel_1149 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
C | GLAT (NRULE_0142) | Glutamine amidotransferase | Xcel_0017 |
DHPS (NRULE_0144) | Dihydropteroate synthase | Xcel_0978 Xcel_2985 |
DFR2 (NRULE_0148) | Dihydrofolate reductase type 2 | |
FOLB (NRULE_0158) | Dihydroneopterin aldolase | Xcel_2984 |
FOLK (NRULE_0159) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | Xcel_2984 |
FOLC (NRULE_0160) | Bifunctional protein FolC | Xcel_1149 |
PABB (NRULE_0161) | Para-aminobenzoate synthase component I | |
PABC (NRULE_0162) | Aminodeoxychorismate lyase | |
Gentamicin resistance(NFUNC_0053) |
必須 | A | ANT2 (NRULE_0153) | 2''-aminoglycoside nucleotidyltransferase | |
任意 | | AAC3 (NRULE_0149) | Aminoglycoside N(3')-acetyltransferase | Xcel_0724 |
Human milk oligosaccharides metabolism(NFUNC_0083) |
必須 | A | LNBP (NRULE_0112) | 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase | |
任意 | | NAHK (NRULE_0256) | N-acetylhexosamine 1-kinase | |
| GALT (NRULE_0110) | Galactose-1-phosphate uridylyltransferase | |
| GALE (NRULE_0111) | UDP-glucose 4-epimerase | Xcel_3082 |
4-hydroxyphenylacetate degradation(NFUNC_0068) |
必須 | A | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component | |
HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
B | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component | |
HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
C | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_0311 Xcel_1979 |
HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
D | HPAB1 (NRULE_0085) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_0311 Xcel_1979 |
HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
E | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_1979 Xcel_0311 |
HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
F | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_1979 Xcel_0311 |
HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
G | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component | |
HPAD2 (NRULE_0194) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
H | HPAB2 (NRULE_0086) | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | |
HPAC (NRULE_0102) | 4-hydroxyphenylacetate 3-monooxygenase reductase component | |
HPAD1 (NRULE_0193) | Homoprotocatechuate 2,3-dioxygenase | |
HPAE (NRULE_0195) | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase | |
HPAF (NRULE_0196) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase | |
HPAG (NRULE_0197) | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase | |
HPAH (NRULE_0198) | 2-oxo-hepta-3-ene-1,7-dioate hydratase | |
HPAI (NRULE_0199) | 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase | |
Kanamycin resistance(NFUNC_0052) |
必須 | A | ANT4 (NRULE_0152) | Kanamycin nucleotidyltransferase | |
B | ANT2 (NRULE_0153) | 2''-aminoglycoside nucleotidyltransferase | |
C | APH3 (NRULE_0156) | Aminoglycoside 3'-phosphotransferase | |
任意 | | AAC3 (NRULE_0149) | Aminoglycoside N(3')-acetyltransferase | Xcel_0724 |
| AAC6 (NRULE_0150) | Aminoglycoside N(6')-acetyltransferase | |
Macrolide antibiotic resistance(NFUNC_0045) |
必須 | A | ERM (NRULE_0164) | rRNA adenine N-6-methyltransferase | |
B | RLMA (NRULE_0165) | 23S rRNA (guanine-N(1))-methyltransferase | |
C | MACA (NRULE_0166) | Macrolide-specific efflux protein MacA | |
MACB (NRULE_0167) | Macrolide export ATP-binding/permease protein MacB | |
D | ERE (NRULE_0168) | Erythromycin esterase | |
E | MPH (NRULE_0169) | Macrolide 2'-phosphotransferase | Xcel_2821 |
F | MGT (NRULE_0170) | Macrolide glycosyltransferase | |
Metal-binding protein(NFUNC_0105) |
必須 | A | MOP (NRULE_0322) | Putative molybdenum-binding protein | Xcel_2807 Xcel_2810 |
B | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | |
C | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | Xcel_2808 Xcel_2993 |
D | MNTR (NRULE_0327) | DtxR family transcriptional regulator MntR | |
E | CUER (NRULE_0328) | Copper-responsive transcriptional regulator CueR | |
F | SOXR (NRULE_0329) | Redox-sensitive transcriptional activator SoxR | |
G | ZNTR (NRULE_0330) | Zinc-responsive transcriptional regulator ZntR | |
H | NIKR (NRULE_0331) | Nickel-responsive transcriptional regulator NikR | |
I | ISCR (NRULE_0332) | Rrf2 family transcriptional regulator IscR | |
J | SMTA (NRULE_0009) | Metallothionein | |
Molybdate transport (ABC transporter)(NFUNC_0097) |
必須 | A | MODA (NRULE_0324) | Molybdate ABC transporter substrate-binding protein | Xcel_2993 Xcel_2808 |
任意 | | MODE (NRULE_0323) | Putative molybdate-dependent transcriptional regulator | |
| MODB (NRULE_0325) | Molybdate ABC transporter permease protein | Xcel_2809 |
| MODC (NRULE_0326) | Molybdate ABC transporter ATP-binding protein | |
Naphthalene degradation (via hydroxylation by dioxygenase)(NFUNC_0067) |
必須 | A | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit | |
RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit | |
CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase | |
EDIO (NRULE_0058) | extradiol dioxygenase | |
NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase | |
NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | |
NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase | |
NAHG (NRULE_0190) | Salicylate hydroxylase | |
B | RHDA (NRULE_0048) | Ring-hydroxylating dioxygenase alpha subunit | |
RHDB (NRULE_0049) | Ring-hydroxylating dioxygenase beta subunit | |
CDDH (NRULE_0056) | Cis-dihydrodiol dehydrogenase | |
EDIO (NRULE_0058) | extradiol dioxygenase | |
NAHD (NRULE_0171) | 2-hydroxychromene-2-carboxylate isomerase | |
NAHE (NRULE_0172) | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | |
NAHF (NRULE_0173) | Salicylaldehyde dehydrogenase | |
NAGG (NRULE_0191) | Salicylate 5-hydroxylase alpha subunit | |
NAGH (NRULE_0192) | Salicylate 5-hydroxylase beta subunit | |
任意 | | FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_1306 Xcel_1359 Xcel_2010 Xcel_2768 |
| FDR2 (NRULE_0057) | Ferredoxin reductase | |
(R)-pantothenate biosynthesis(NFUNC_0030) |
必須 | A | PAND (NRULE_0115) | Aspartate 1-decarboxylase | Xcel_1645 |
PANB (NRULE_0116) | 3-methyl-2-oxobutanoate hydroxymethyltransferase | Xcel_1646 |
PANE (NRULE_0117) | 2-dehydropantoate 2-reductase | |
PANC (NRULE_0118) | Pantothenate synthetase | Xcel_1644 |
Penicillin resistance(NFUNC_0047) |
必須 | A | BLAA (NRULE_0122) | Beta-lactamase class A | |
B | BLAD (NRULE_0125) | Beta-lactamase class D | Xcel_3275 |
任意 | | BLAB (NRULE_0123) | Metallo-beta-lactamase | |
Phenol degradation(NFUNC_0028) |
必須 | A | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit | |
MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit | |
MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit | |
B | PHEA1 (NRULE_0083) | Aromatic ring hydroxylase | |
C | PHEA2 (NRULE_0084) | Aromatic ring hydroxylase | |
任意 | | FDR2 (NRULE_0057) | Ferredoxin reductase | |
| FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
| MME (NRULE_0033) | Multicomponent monooxygenase effector protein | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_2010 Xcel_2768 Xcel_1359 Xcel_1306 |
| FADR1 (NRULE_0101) | NADH-dependent flavin reductase | Xcel_0311 Xcel_1979 |
Riboflavin biosynthesis(NFUNC_0058) |
必須 | A | RIBB (NRULE_0200) | 3,4-dihydroxy-2-butanone 4-phosphate synthase | Xcel_1728 |
RIBA (NRULE_0201) | GTP cyclohydrolase-2 | Xcel_1728 |
RIBD (NRULE_0202) | Riboflavin biosynthesis protein RibD | |
RIBH (NRULE_0203) | 6,7-dimethyl-8-ribityllumazine synthase | Xcel_1729 |
RIBE (NRULE_0204) | Riboflavin synthase | Xcel_1727 |
任意 | | RIBF (NRULE_0205) | Riboflavin biosynthesis protein RibF | Xcel_1215 |
Streptomycin resistance(NFUNC_0054) |
必須 | A | ANT6 (NRULE_0151) | Aminoglycoside 6-adenylyltransferase | |
B | ANT3 (NRULE_0154) | Streptomycin 3''-adenylyltransferase | |
C | APH6 (NRULE_0155) | Streptomycin 6-kinase | Xcel_0261 |
任意 | | APH3 (NRULE_0156) | Aminoglycoside 3'-phosphotransferase | |
Toluene degradation (conversion into protocatechuate via p-cresol)(NFUNC_0007) |
必須 | A | MMA (NRULE_0027) | Multicomponent monooxygenase alpha subunit | |
MMB (NRULE_0028) | Multicomponent monooxygenase beta subunit | |
FDR1 (NRULE_0032) | Oxygenase electron transfer component | |
MME (NRULE_0033) | Multicomponent monooxygenase effector protein | |
PCHF (NRULE_0035) | 4-cresol dehydrogenase flavoprotein subunit | |
PCHC (NRULE_0036) | 4-cresol dehydrogenase cytochrome c subunit | |
PCHA (NRULE_0037) | p-hydroxybenzaldehyde dehydrogenase | |
POBA (NRULE_0038) | p-hydroxybenzoate hydroxylase | |
任意 | | MMG1 (NRULE_0029) | Multicomponent monooxygenase gamma subunit | |
| MMG2 (NRULE_0030) | Multicomponent monooxygenase gamma subunit | |
| MMG3 (NRULE_0031) | Multicomponent monooxygenase gamma subunit | |
| FDX1 (NRULE_0034) | Putative Rieske-type ferredoxin | Xcel_2768 Xcel_1306 Xcel_1359 Xcel_2010 |
Trehalose biosynthesis (from maltooligosaccharide)(NFUNC_0037) |
必須 | A | TREY (NRULE_0140) | Maltooligosyl trehalose synthase | |
TREZ (NRULE_0141) | Malto-oligosyltrehalose trehalohydrolase | |
任意 | | GLGX (NRULE_0139) | Glycogen debranching enzyme | Xcel_2413 |
Trehalose biosynthesis (from maltose)(NFUNC_0034) |
必須 | A | MAPA (NRULE_0126) | Maltose phosphorylase | |
TREP (NRULE_0127) | Alpha,alpha-trehalose phosphorylase | |
B | TRES (NRULE_0128) | Trehalose synthase | Xcel_2418 |
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031) |
必須 | A | TPS (NRULE_0119) | Trehalose-phosphate synthase | Xcel_2949 |
TPP (NRULE_0120) | Trehalose-6-phosphate phosphatase | Xcel_2949 |
Uptake of osmoprotectant(NFUNC_0061) |
必須 | A | OPUAC (NRULE_0213) | Osmoprotectant ABC transporter substrate-binding protein | |
OPUAB (NRULE_0214) | Osmoprotectant ABC transporter permease protein | |
OPUAA (NRULE_0215) | Osmoprotectant ABC transporter ATP-binding protein | Xcel_2529 |
B | EHUB (NRULE_0216) | Ectoine ABC transporter substrate-binding protein | |
EHUC (NRULE_0217) | Ectoine ABC transporter permease protein | |
EHUD (NRULE_0218) | Ectoine ABC transporter permease protein | |
EHUA (NRULE_0219) | Ectoine ABC transporter ATP-binding protein | |
C | BCCT (NRULE_0220) | BCCT family transporter | Xcel_2261 |
D | PROP (NRULE_0221) | Osmoprotectant transporter | |
E | OPUE (NRULE_0222) | Sodium/proline symporter | |
F | TEAA (NRULE_0223) | TRAP transporter substrate-binding protein TeaA | |
TEAB (NRULE_0224) | TRAP transporter small transmembrane protein TeaB | |
TEAC (NRULE_0225) | TRAP transporter large transmembrane protein TeaC | |
Vancomycin resistance (via D-Ala-D-Lac precursor)(NFUNC_0089) |
必須 | A | VANA (NRULE_0265) | D-alanine--D-lactate ligase | |
VANH (NRULE_0266) | D-specific alpha-keto acid dehydrogenase | |
VANX (NRULE_0267) | D-alanyl-D-alanine dipeptidase | |
任意 | | VANYA (NRULE_0274) | D-alanyl-D-alanine carboxypeptidase | |
| VANYB (NRULE_0275) | D-alanyl-D-alanine carboxypeptidase | |
| VANYD (NRULE_0276) | D-alanyl-D-alanine carboxypeptidase | |
| VANY (NRULE_0277) | D-alanyl-D-alanine carboxypeptidase | |
| VANYN (NRULE_0278) | D-alanyl-D-alanine dipeptidase/D-alanyl-D-alanine carboxypeptidase | |
| VANRA (NRULE_0279) | Two-component system response regulator VanR | |
| VANRB (NRULE_0280) | Two-component system response regulator VanR | |
| VANRD (NRULE_0282) | Putative two-component system response regulator VanR | |
| VANR (NRULE_0284) | Two-component system response regulator VanR | Xcel_1424 |
| VANSA (NRULE_0285) | Two-component system histidine kinase VanS | |
| VANSB (NRULE_0286) | Two-component system histidine kinase VanS | |
| VANSD (NRULE_0288) | Putative two-component system histidine kinase VanS | |
| VANSM (NRULE_0289) | Putative two-component system histidine kinase VanS | |
| VANS (NRULE_0290) | Two-component system histidine kinase VanS | Xcel_1425 |
| VANZ (NRULE_0291) | Teicoplanin resistance protein | |
| VANW (NRULE_0292) | Putative vancomycin resistance protein | |
| VANJ (NRULE_0295) | Teicoplanin resistance protein | |
| VANK (NRULE_0296) | Glycyltransferase VanK | |
| MURF2 (NRULE_0297) | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-lactate ligase | |
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059) |
必須 | A | PDXS (NRULE_0206) | Pyridoxal biosynthesis lyase PdxS | Xcel_1662 |
PDXT (NRULE_0207) | Glutamine amidotransferase subunit PdxT | Xcel_1664 |