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推定保有機能 : Saccharopolyspora spinosa

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タイプパターン 構成遺伝子 該当CDS
Acid resistance (by GABA antiporter)(NFUNC_0071)
必須A
GAD
(NRULE_0231)
Glutamate decarboxylaseSspiN1_010100019621 SspiN1_010100035499
GADC
(NRULE_0234)
Glutamate/gamma-aminobutyrate antiporter
Alanine racemization(NFUNC_0063)
必須A
ALR
(NRULE_0228)
Alanine racemaseSspiN1_010100040910
n-alkane hydroxylation(NFUNC_0008)
必須A
CYP153
(NRULE_0041)
Cytochrome P450 CYP153
B
ALKB
(NRULE_0024)
Alkane 1-monooxygenase
C
MMA
(NRULE_0027)
Multicomponent monooxygenase alpha subunit
MMB
(NRULE_0028)
Multicomponent monooxygenase beta subunit
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100038044 SspiN1_010100005705 SspiN1_010100008225 SspiN1_010100028199
MME
(NRULE_0033)
Multicomponent monooxygenase effector protein
任意 
RUBA
(NRULE_0039)
Rubredoxin
 
RUBB
(NRULE_0040)
Rubredoxin reductase
 
MMG1
(NRULE_0029)
Multicomponent monooxygenase gamma subunit
 
MMG2
(NRULE_0030)
Multicomponent monooxygenase gamma subunit
 
MMG3
(NRULE_0031)
Multicomponent monooxygenase gamma subunit
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100003433 SspiN1_010100007060 SspiN1_010100038049 SspiN1_010100037354 SspiN1_010100024527 SspiN1_010100013249 SspiN1_010100007230 SspiN1_010100007240 SspiN1_010100003423 SspiN1_010100008220
Aminoglycoside resistance (by aminoglycoside O-phosphotransferase)(NFUNC_0043)
必須A
APH6
(NRULE_0155)
Streptomycin 6-kinaseSspiN1_010100006375 SspiN1_010100015100
B
APH3
(NRULE_0156)
Aminoglycoside 3'-phosphotransferase
C
APH7
(NRULE_0157)
Hygromycin-B 7''-O-kinase
D
HPH
(NRULE_0174)
Hygromycin-B 4-O-kinase
Ampicillin resistance(NFUNC_0046)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASspiN1_010100034029
任意 
BLAB
(NRULE_0123)
Metallo-beta-lactamase
 
BLAD
(NRULE_0125)
Beta-lactamase class D
Aniline degradation (conversion into catechol)(NFUNC_0075)
必須A
ATDA1
(NRULE_0240)
Gamma-glutamylanilide synthetase
ATDA3
(NRULE_0357)
Aniline dioxygenase large subunit
ATDA4
(NRULE_0358)
Aniline dioxygenase small subunit
任意 
ATDA2
(NRULE_0241)
Putative gamma-glutamylanilide hydrolase
 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100008225 SspiN1_010100005705 SspiN1_010100038044 SspiN1_010100028199
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100007240 SspiN1_010100007230 SspiN1_010100003433 SspiN1_010100003423 SspiN1_010100038049 SspiN1_010100007060 SspiN1_010100037354 SspiN1_010100024527 SspiN1_010100013249 SspiN1_010100008220
 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100024537 SspiN1_010100003418 SspiN1_010100003953
Anthranilate biosynthesis(NFUNC_0038)
必須A
GLAT
(NRULE_0142)
Glutamine amidotransferaseSspiN1_010100013900 SspiN1_010100016231 SspiN1_010100032954 SspiN1_010100022915
TRPE
(NRULE_0143)
Anthranilate synthase component ISspiN1_010100003268
Anthranilate degradation (via hydroxylation)(NFUNC_0018)
必須A
ANTA
(NRULE_0044)
Anthranilate 1,2-dioxygenase large subunit
ANTB
(NRULE_0045)
Anthranilate 1,2-dioxygenase small subunit
任意 
ANTC
(NRULE_0081)
Anthranilate 1,2-dioxygenase electron transfer component
 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100038044 SspiN1_010100028199 SspiN1_010100008225 SspiN1_010100005705
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100037354 SspiN1_010100038049 SspiN1_010100003423 SspiN1_010100003433 SspiN1_010100007060 SspiN1_010100007230 SspiN1_010100007240 SspiN1_010100008220 SspiN1_010100013249 SspiN1_010100024527
 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100024537 SspiN1_010100003953 SspiN1_010100003418
Aromatic hydrocarbon degradation (via hydroxylation by dioxygenase)(NFUNC_0016)
必須A
RHDA
(NRULE_0048)
Ring-hydroxylating dioxygenase alpha subunitSspiN1_010100008220 SspiN1_010100003433 SspiN1_010100007230
RHDB
(NRULE_0049)
Ring-hydroxylating dioxygenase beta subunitSspiN1_010100036629 SspiN1_010100027819
CDDH
(NRULE_0056)
Cis-dihydrodiol dehydrogenase
任意 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100038044 SspiN1_010100028199 SspiN1_010100008225 SspiN1_010100005705
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100003433 SspiN1_010100038049 SspiN1_010100037354 SspiN1_010100024527 SspiN1_010100013249 SspiN1_010100008220 SspiN1_010100003423 SspiN1_010100007240 SspiN1_010100007230 SspiN1_010100007060
 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100003418 SspiN1_010100024537 SspiN1_010100003953
Arsenical resistance(NFUNC_0004)
必須A
ARSB1
(NRULE_0015)
Arsenical pump membrane protein
ARSC1
(NRULE_0017)
Arsenate reductase
B
ARSB1
(NRULE_0015)
Arsenical pump membrane protein
ARSC2
(NRULE_0018)
Arsenate reductase
C
ARSB1
(NRULE_0015)
Arsenical pump membrane protein
ARSC3
(NRULE_0019)
Arsenate reductase
D
ARSB2
(NRULE_0016)
Arsenite resistance protein ArsBSspiN1_010100030174
ARSC1
(NRULE_0017)
Arsenate reductase
E
ARSB2
(NRULE_0016)
Arsenite resistance protein ArsBSspiN1_010100030174
ARSC2
(NRULE_0018)
Arsenate reductase
F
ARSB2
(NRULE_0016)
Arsenite resistance protein ArsBSspiN1_010100030174
ARSC3
(NRULE_0019)
Arsenate reductase
任意 
ARSA
(NRULE_0014)
Arsenical pump-driving ATPaseSspiN1_010100013194
 
ARSD
(NRULE_0020)
Arsenical resistance operon trans-acting repressor ArsD
 
ARSH
(NRULE_0021)
ArsH protein
Artificial lacto-N-biose biosynthesis(NFUNC_0026)
必須A
SP
(NRULE_0109)
Sucrose phosphorylase
GALT
(NRULE_0110)
Galactose-1-phosphate uridylyltransferaseSspiN1_010100041500
GALE
(NRULE_0111)
UDP-glucose 4-epimeraseSspiN1_010100012839
LNBP
(NRULE_0112)
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase
Bacitracin resistance(NFUNC_0022)
必須A
UPPP
(NRULE_0097)
Undecaprenyl-diphosphataseSspiN1_010100005870
Benzoate degradation (via hydroxylation by dioxygenase)(NFUNC_0017)
必須A
BENA
(NRULE_0046)
Benzoate 1,2-dioxygenase alpha subunit
BENB
(NRULE_0047)
Benzoate 1,2-dioxygenase beta subunit
BEND
(NRULE_0082)
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
任意 
BENC
(NRULE_0055)
Benzoate 1,2-dioxygenase electron transfer component
 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100028199 SspiN1_010100008225 SspiN1_010100005705 SspiN1_010100038044
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100037354 SspiN1_010100013249 SspiN1_010100008220 SspiN1_010100007240 SspiN1_010100007230 SspiN1_010100007060 SspiN1_010100003423 SspiN1_010100003433 SspiN1_010100038049 SspiN1_010100024527
 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100024537 SspiN1_010100003418 SspiN1_010100003953
Beta-lactam antibiotic resistance(NFUNC_0033)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASspiN1_010100034029
B
BLAB
(NRULE_0123)
Metallo-beta-lactamase
C
BLAC
(NRULE_0124)
Beta-lactamase class C
D
BLAD
(NRULE_0125)
Beta-lactamase class D
Betaine biosynthesis (from choline)(NFUNC_0049)
必須A
BETA
(NRULE_0175)
Choline dehydrogenase
B
GBSB
(NRULE_0176)
Alcohol dehydrogenase
BETB
(NRULE_0177)
Betaine aldehyde dehydrogenaseSspiN1_010100019536
C
CHOX
(NRULE_0178)
Choline oxidaseSspiN1_010100019521
Betaine biosynthesis (from glycine)(NFUNC_0050)
必須A
GSMT
(NRULE_0179)
Glycine/sarcosine N-methyltransferase
SDMT
(NRULE_0180)
Dimethylglycine N-methyltransferase
B
GSDMT
(NRULE_0181)
Glycine/sarcosine/dimethylglycine N-methyltransferaseSspiN1_010100028469
Biotin biosynthesis(NFUNC_0051)
必須A
BIOF
(NRULE_0182)
8-amino-7-oxononanoate synthase
BIOA
(NRULE_0183)
Adenosylmethionine-8-amino-7-oxononanoate aminotransferaseSspiN1_010100017361
BIOD
(NRULE_0184)
ATP-dependent dethiobiotin synthetase BioDSspiN1_010100017371
BIOB
(NRULE_0185)
Biotin synthaseSspiN1_010100017356
Catechol degradation (beta-ketoadipate pathway)(NFUNC_0013)
必須A
CATA
(NRULE_0052)
Catechol 1,2-dioxygenase
CATB2
(NRULE_0053)
(Chloro)muconate cycloisomerase
CATC
(NRULE_0054)
Muconolactone isomerase
PCAD
(NRULE_0070)
3-oxoadipate enol-lactonaseSspiN1_010100004753 SspiN1_010100033004
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
B
CATA
(NRULE_0052)
Catechol 1,2-dioxygenase
CATC
(NRULE_0054)
Muconolactone isomerase
PCAD
(NRULE_0070)
3-oxoadipate enol-lactonaseSspiN1_010100004753 SspiN1_010100033004
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
CATB1
(NRULE_0386)
Muconate cycloisomerase
C
CATA
(NRULE_0052)
Catechol 1,2-dioxygenase
CATC
(NRULE_0054)
Muconolactone isomerase
PCAL
(NRULE_0071)
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
CATB1
(NRULE_0386)
Muconate cycloisomerase
D
CATA
(NRULE_0052)
Catechol 1,2-dioxygenase
CATB2
(NRULE_0053)
(Chloro)muconate cycloisomerase
CATC
(NRULE_0054)
Muconolactone isomerase
PCAL
(NRULE_0071)
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
Cephalosporin resistance(NFUNC_0048)
必須A
BLAC
(NRULE_0124)
Beta-lactamase class C
任意 
BLAA
(NRULE_0122)
Beta-lactamase class ASspiN1_010100034029
 
BLAB
(NRULE_0123)
Metallo-beta-lactamase
Chlorocatechol degradation (beta-ketoadipate pathway)(NFUNC_0104)
必須A
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
CLCA
(NRULE_0382)
Chlorocatechol 1,2-dioxygenase
CLCD
(NRULE_0383)
Dienelactone hydrolaseSspiN1_010100009473 SspiN1_010100007130 SspiN1_010100008580 SspiN1_010100011309 SspiN1_010100018426 SspiN1_010100019096 SspiN1_010100019361 SspiN1_010100020081 SspiN1_010100020374 SspiN1_010100040925
CLCE
(NRULE_0384)
Maleylacetate reductase
CLCB
(NRULE_0387)
Chloromuconate cycloisomerase
B
CATB2
(NRULE_0053)
(Chloro)muconate cycloisomerase
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
CLCA
(NRULE_0382)
Chlorocatechol 1,2-dioxygenase
CLCD
(NRULE_0383)
Dienelactone hydrolaseSspiN1_010100011309 SspiN1_010100040925 SspiN1_010100020374 SspiN1_010100020081 SspiN1_010100019361 SspiN1_010100019096 SspiN1_010100018426 SspiN1_010100007130 SspiN1_010100008580 SspiN1_010100009473
CLCE
(NRULE_0384)
Maleylacetate reductase
任意 
CLCF
(NRULE_0385)
Chloromuconolactone dehalogenase
Dibenzothiophene degradation (via desulfurization)(NFUNC_0029)
必須A
DSZA
(NRULE_0103)
Dibenzothiophene-5,5-dioxide monooxygenase
DSZB
(NRULE_0104)
2'-hydroxybiphenyl-2-sulfinate desulfinase
DSZC
(NRULE_0105)
Dibenzothiophene monooxygenase
任意 
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100027864 SspiN1_010100039744 SspiN1_010100037654 SspiN1_010100037434 SspiN1_010100010889 SspiN1_010100036699
Dihydroxy aromatic compounds degradation (via meta-cleavage pathway)(NFUNC_0011)
必須A
EDIO
(NRULE_0058)
extradiol dioxygenaseSspiN1_010100008998
METAH
(NRULE_0059)
meta-cleavage compound hydrolase
HPDH
(NRULE_0063)
2-hydroxypent-2,4-dienoate hydratase
HOA
(NRULE_0064)
4-hydroxy-2-oxovalerate aldolase
ACDH
(NRULE_0065)
Acetaldehyde dehydrogenase
B
EDIO
(NRULE_0058)
extradiol dioxygenaseSspiN1_010100008998
2HMSD
(NRULE_0060)
2-hydroxymuconic semialdehyde dehydrogenase
4OT
(NRULE_0061)
4-oxalocrotonate tautomerase
4OD
(NRULE_0062)
4-oxalocrotonate decarboxylase
HPDH
(NRULE_0063)
2-hydroxypent-2,4-dienoate hydratase
HOA
(NRULE_0064)
4-hydroxy-2-oxovalerate aldolase
ACDH
(NRULE_0065)
Acetaldehyde dehydrogenase
Ectoine biosynthesis(NFUNC_0056)
必須A
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseSspiN1_010100021358
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseSspiN1_010100021363
ECTC
(NRULE_0188)
L-ectoine synthaseSspiN1_010100021353
Folate biosynthesis(NFUNC_0044)
必須A
GLAT
(NRULE_0142)
Glutamine amidotransferaseSspiN1_010100013900 SspiN1_010100016231 SspiN1_010100022915 SspiN1_010100032954
DHPS
(NRULE_0144)
Dihydropteroate synthaseSspiN1_010100010289 SspiN1_010100007180 SspiN1_010100021123 SspiN1_010100023887
FOLM
(NRULE_0146)
Dihydrofolate reductase FolM
FOLB
(NRULE_0158)
Dihydroneopterin aldolaseSspiN1_010100021128
FOLK
(NRULE_0159)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseSspiN1_010100021133
FOLC
(NRULE_0160)
Bifunctional protein FolCSspiN1_010100015010
PABB
(NRULE_0161)
Para-aminobenzoate synthase component ISspiN1_010100022915 SspiN1_010100016231 SspiN1_010100041375
PABC
(NRULE_0162)
Aminodeoxychorismate lyase
B
GLAT
(NRULE_0142)
Glutamine amidotransferaseSspiN1_010100013900 SspiN1_010100022915 SspiN1_010100032954 SspiN1_010100016231
DHPS
(NRULE_0144)
Dihydropteroate synthaseSspiN1_010100007180 SspiN1_010100010289 SspiN1_010100023887 SspiN1_010100021123
FOLA
(NRULE_0147)
Dihydrofolate reductase
FOLB
(NRULE_0158)
Dihydroneopterin aldolaseSspiN1_010100021128
FOLK
(NRULE_0159)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseSspiN1_010100021133
FOLC
(NRULE_0160)
Bifunctional protein FolCSspiN1_010100015010
PABB
(NRULE_0161)
Para-aminobenzoate synthase component ISspiN1_010100016231 SspiN1_010100022915 SspiN1_010100041375
PABC
(NRULE_0162)
Aminodeoxychorismate lyase
C
GLAT
(NRULE_0142)
Glutamine amidotransferaseSspiN1_010100016231 SspiN1_010100032954 SspiN1_010100022915 SspiN1_010100013900
DHPS
(NRULE_0144)
Dihydropteroate synthaseSspiN1_010100021123 SspiN1_010100010289 SspiN1_010100007180 SspiN1_010100023887
DFR2
(NRULE_0148)
Dihydrofolate reductase type 2
FOLB
(NRULE_0158)
Dihydroneopterin aldolaseSspiN1_010100021128
FOLK
(NRULE_0159)
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseSspiN1_010100021133
FOLC
(NRULE_0160)
Bifunctional protein FolCSspiN1_010100015010
PABB
(NRULE_0161)
Para-aminobenzoate synthase component ISspiN1_010100016231 SspiN1_010100022915 SspiN1_010100041375
PABC
(NRULE_0162)
Aminodeoxychorismate lyase
GABA biosynthesis(NFUNC_0066)
必須A
GAD
(NRULE_0231)
Glutamate decarboxylaseSspiN1_010100035499 SspiN1_010100019621
Haloalkane degradation (conversion into hydroxyacid)(NFUNC_0010)
必須A
DHAA
(NRULE_0050)
Haloalkane dehalogenase
HAD
(NRULE_0051)
(S)-2-haloacid dehalogenaseSspiN1_010100031919 SspiN1_010100028779 SspiN1_010100007020
B
DHAA
(NRULE_0050)
Haloalkane dehalogenase
DEH
(NRULE_0075)
Haloacetate dehalogenase
Human milk oligosaccharides metabolism(NFUNC_0083)
必須A
LNBP
(NRULE_0112)
1,3-beta-galactosyl-N-acetylhexosamine phosphorylase
任意 
NAHK
(NRULE_0256)
N-acetylhexosamine 1-kinase
 
GALT
(NRULE_0110)
Galactose-1-phosphate uridylyltransferaseSspiN1_010100041500
 
GALE
(NRULE_0111)
UDP-glucose 4-epimeraseSspiN1_010100012839
Hydroxyectoine biosynthesis(NFUNC_0057)
必須A
ECTD
(NRULE_0189)
Ectoine hydroxylaseSspiN1_010100021348
任意 
ECTB
(NRULE_0186)
Diaminobutyrate--2-oxoglutarate transaminaseSspiN1_010100021358
 
ECTA
(NRULE_0187)
L-2,4-diaminobutyric acid acetyltransferaseSspiN1_010100021363
 
ECTC
(NRULE_0188)
L-ectoine synthaseSspiN1_010100021353
4-hydroxyphenylacetate degradation(NFUNC_0068)
必須A
HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
HPAC
(NRULE_0102)
4-hydroxyphenylacetate 3-monooxygenase reductase component
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
B
HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
HPAC
(NRULE_0102)
4-hydroxyphenylacetate 3-monooxygenase reductase component
HPAD2
(NRULE_0194)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
C
HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100037434 SspiN1_010100039744 SspiN1_010100037654 SspiN1_010100010889 SspiN1_010100027864 SspiN1_010100036699
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
D
HPAB1
(NRULE_0085)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100036699 SspiN1_010100027864 SspiN1_010100010889 SspiN1_010100037434 SspiN1_010100037654 SspiN1_010100039744
HPAD2
(NRULE_0194)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
E
HPAB2
(NRULE_0086)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100037434 SspiN1_010100010889 SspiN1_010100027864 SspiN1_010100036699 SspiN1_010100037654 SspiN1_010100039744
HPAD2
(NRULE_0194)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
F
HPAB2
(NRULE_0086)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100036699 SspiN1_010100010889 SspiN1_010100027864 SspiN1_010100037434 SspiN1_010100037654 SspiN1_010100039744
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
G
HPAB2
(NRULE_0086)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
HPAC
(NRULE_0102)
4-hydroxyphenylacetate 3-monooxygenase reductase component
HPAD2
(NRULE_0194)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
H
HPAB2
(NRULE_0086)
4-hydroxyphenylacetate 3-monooxygenase oxygenase component
HPAC
(NRULE_0102)
4-hydroxyphenylacetate 3-monooxygenase reductase component
HPAD1
(NRULE_0193)
Homoprotocatechuate 2,3-dioxygenase
HPAE
(NRULE_0195)
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
HPAF
(NRULE_0196)
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
HPAG
(NRULE_0197)
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate Delta-isomerase
HPAH
(NRULE_0198)
2-oxo-hepta-3-ene-1,7-dioate hydratase
HPAI
(NRULE_0199)
2,4-dihydroxyhept-2-ene-1,7-dioate aldolase
Macrolide antibiotic resistance(NFUNC_0045)
必須A
ERM
(NRULE_0164)
rRNA adenine N-6-methyltransferase
B
RLMA
(NRULE_0165)
23S rRNA (guanine-N(1))-methyltransferaseSspiN1_010100027544
C
MACA
(NRULE_0166)
Macrolide-specific efflux protein MacA
MACB
(NRULE_0167)
Macrolide export ATP-binding/permease protein MacB
D
ERE
(NRULE_0168)
Erythromycin esteraseSspiN1_010100041750 SspiN1_010100005905
E
MPH
(NRULE_0169)
Macrolide 2'-phosphotransferase
F
MGT
(NRULE_0170)
Macrolide glycosyltransferase
Metal-binding protein(NFUNC_0105)
必須A
MOP
(NRULE_0322)
Putative molybdenum-binding proteinSspiN1_010100021915 SspiN1_010100022765 SspiN1_010100021900
B
MODE
(NRULE_0323)
Putative molybdate-dependent transcriptional regulator
C
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinSspiN1_010100017626 SspiN1_010100021905
D
MNTR
(NRULE_0327)
DtxR family transcriptional regulator MntR
E
CUER
(NRULE_0328)
Copper-responsive transcriptional regulator CueR
F
SOXR
(NRULE_0329)
Redox-sensitive transcriptional activator SoxRSspiN1_010100003223
G
ZNTR
(NRULE_0330)
Zinc-responsive transcriptional regulator ZntR
H
NIKR
(NRULE_0331)
Nickel-responsive transcriptional regulator NikR
I
ISCR
(NRULE_0332)
Rrf2 family transcriptional regulator IscR
J
SMTA
(NRULE_0009)
Metallothionein
Molybdate transport (ABC transporter)(NFUNC_0097)
必須A
MODA
(NRULE_0324)
Molybdate ABC transporter substrate-binding proteinSspiN1_010100021905 SspiN1_010100017626
任意 
MODE
(NRULE_0323)
Putative molybdate-dependent transcriptional regulator
 
MODB
(NRULE_0325)
Molybdate ABC transporter permease proteinSspiN1_010100021910
 
MODC
(NRULE_0326)
Molybdate ABC transporter ATP-binding protein
Naphthalene degradation (via hydroxylation by dioxygenase)(NFUNC_0067)
必須A
RHDA
(NRULE_0048)
Ring-hydroxylating dioxygenase alpha subunitSspiN1_010100007230 SspiN1_010100008220 SspiN1_010100003433
RHDB
(NRULE_0049)
Ring-hydroxylating dioxygenase beta subunitSspiN1_010100036629 SspiN1_010100027819
CDDH
(NRULE_0056)
Cis-dihydrodiol dehydrogenase
EDIO
(NRULE_0058)
extradiol dioxygenaseSspiN1_010100008998
NAHD
(NRULE_0171)
2-hydroxychromene-2-carboxylate isomerase
NAHE
(NRULE_0172)
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
NAHF
(NRULE_0173)
Salicylaldehyde dehydrogenase
NAHG
(NRULE_0190)
Salicylate hydroxylase
B
RHDA
(NRULE_0048)
Ring-hydroxylating dioxygenase alpha subunitSspiN1_010100003433 SspiN1_010100008220 SspiN1_010100007230
RHDB
(NRULE_0049)
Ring-hydroxylating dioxygenase beta subunitSspiN1_010100036629 SspiN1_010100027819
CDDH
(NRULE_0056)
Cis-dihydrodiol dehydrogenase
EDIO
(NRULE_0058)
extradiol dioxygenaseSspiN1_010100008998
NAHD
(NRULE_0171)
2-hydroxychromene-2-carboxylate isomerase
NAHE
(NRULE_0172)
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
NAHF
(NRULE_0173)
Salicylaldehyde dehydrogenase
NAGG
(NRULE_0191)
Salicylate 5-hydroxylase alpha subunit
NAGH
(NRULE_0192)
Salicylate 5-hydroxylase beta subunit
任意 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100005705 SspiN1_010100008225 SspiN1_010100028199 SspiN1_010100038044
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100003423 SspiN1_010100013249 SspiN1_010100008220 SspiN1_010100007240 SspiN1_010100007230 SspiN1_010100007060 SspiN1_010100003433 SspiN1_010100024527 SspiN1_010100037354 SspiN1_010100038049
 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100024537 SspiN1_010100003953 SspiN1_010100003418
Nitrile hydratase(NFUNC_0002)
必須A
NHAA
(NRULE_0001)
Nitrile hydratase subunit alpha
NHAB
(NRULE_0002)
Nitrile hydratase subunit beta
任意 
P14K
(NRULE_0006)
Nitrile hydratase activator P14K
 
COBW
(NRULE_0007)
CobW/P47K family proteinSspiN1_010100005303 SspiN1_010100041530
(R)-pantothenate biosynthesis(NFUNC_0030)
必須A
PAND
(NRULE_0115)
Aspartate 1-decarboxylaseSspiN1_010100021168
PANB
(NRULE_0116)
3-methyl-2-oxobutanoate hydroxymethyltransferaseSspiN1_010100013565
PANE
(NRULE_0117)
2-dehydropantoate 2-reductaseSspiN1_010100012429
PANC
(NRULE_0118)
Pantothenate synthetaseSspiN1_010100021163
Penicillin resistance(NFUNC_0047)
必須A
BLAA
(NRULE_0122)
Beta-lactamase class ASspiN1_010100034029
B
BLAD
(NRULE_0125)
Beta-lactamase class D
任意 
BLAB
(NRULE_0123)
Metallo-beta-lactamase
Phenol degradation(NFUNC_0028)
必須A
MMA
(NRULE_0027)
Multicomponent monooxygenase alpha subunit
MMB
(NRULE_0028)
Multicomponent monooxygenase beta subunit
MMG1
(NRULE_0029)
Multicomponent monooxygenase gamma subunit
B
PHEA1
(NRULE_0083)
Aromatic ring hydroxylase
C
PHEA2
(NRULE_0084)
Aromatic ring hydroxylase
任意 
FDR2
(NRULE_0057)
Ferredoxin reductaseSspiN1_010100003418 SspiN1_010100024537 SspiN1_010100003953
 
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100028199 SspiN1_010100038044 SspiN1_010100008225 SspiN1_010100005705
 
MME
(NRULE_0033)
Multicomponent monooxygenase effector protein
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100038049 SspiN1_010100007230 SspiN1_010100007060 SspiN1_010100003433 SspiN1_010100007240 SspiN1_010100008220 SspiN1_010100013249 SspiN1_010100024527 SspiN1_010100003423 SspiN1_010100037354
 
FADR1
(NRULE_0101)
NADH-dependent flavin reductaseSspiN1_010100036699 SspiN1_010100027864 SspiN1_010100039744 SspiN1_010100037654 SspiN1_010100037434 SspiN1_010100010889
Protocatechuate degradation (beta-ketoadipate pathway)(NFUNC_0014)
必須A
PCAG
(NRULE_0066)
Protocatechuate 3,4-dioxygenase alpha subunitSspiN1_010100004763
PCAH
(NRULE_0067)
Protocatechuate 3,4-dioxygenase beta subunitSspiN1_010100004768
PCAB
(NRULE_0068)
3-carboxy-cis,cis-muconate cycloisomeraseSspiN1_010100004758
PCAC
(NRULE_0069)
4-carboxymuconolactone decarboxylaseSspiN1_010100004748
PCAD
(NRULE_0070)
3-oxoadipate enol-lactonaseSspiN1_010100004753 SspiN1_010100033004
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
B
PCAG
(NRULE_0066)
Protocatechuate 3,4-dioxygenase alpha subunitSspiN1_010100004763
PCAH
(NRULE_0067)
Protocatechuate 3,4-dioxygenase beta subunitSspiN1_010100004768
PCAB
(NRULE_0068)
3-carboxy-cis,cis-muconate cycloisomeraseSspiN1_010100004758
PCAL
(NRULE_0071)
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase
PCAI
(NRULE_0072)
3-oxoadipate CoA-transferase subunit ASspiN1_010100037389
PCAJ
(NRULE_0073)
3-oxoadipate CoA-transferase subunit B
PCAF
(NRULE_0074)
Beta-ketoadipyl-CoA thiolaseSspiN1_010100028869
Pyrroloquinoline quinone biosynthesis(NFUNC_0020)
必須A
PQQC
(NRULE_0092)
Pyrroloquinoline-quinone synthaseSspiN1_010100007100 SspiN1_010100018521
任意 
PQQA
(NRULE_0090)
Coenzyme PQQ synthesis protein A
 
PQQB
(NRULE_0091)
Coenzyme PQQ synthesis protein BSspiN1_010100018516 SspiN1_010100007110
 
PQQD
(NRULE_0093)
Coenzyme PQQ synthesis protein D
 
PQQE
(NRULE_0094)
Coenzyme PQQ synthesis protein ESspiN1_010100018531 SspiN1_010100007105
 
PQQF
(NRULE_0095)
Coenzyme PQQ synthesis protein F
Riboflavin biosynthesis(NFUNC_0058)
必須A
RIBB
(NRULE_0200)
3,4-dihydroxy-2-butanone 4-phosphate synthaseSspiN1_010100016516 SspiN1_010100037664 SspiN1_010100037449 SspiN1_010100036704 SspiN1_010100027859 SspiN1_010100026439
RIBA
(NRULE_0201)
GTP cyclohydrolase-2SspiN1_010100037664 SspiN1_010100037449 SspiN1_010100036704 SspiN1_010100027859 SspiN1_010100026439
RIBD
(NRULE_0202)
Riboflavin biosynthesis protein RibD
RIBH
(NRULE_0203)
6,7-dimethyl-8-ribityllumazine synthaseSspiN1_010100026434
RIBE
(NRULE_0204)
Riboflavin synthaseSspiN1_010100026444
任意 
RIBF
(NRULE_0205)
Riboflavin biosynthesis protein RibFSspiN1_010100002583
Streptomycin resistance(NFUNC_0054)
必須A
ANT6
(NRULE_0151)
Aminoglycoside 6-adenylyltransferase
B
ANT3
(NRULE_0154)
Streptomycin 3''-adenylyltransferase
C
APH6
(NRULE_0155)
Streptomycin 6-kinaseSspiN1_010100015100 SspiN1_010100006375
任意 
APH3
(NRULE_0156)
Aminoglycoside 3'-phosphotransferase
Toluene degradation (conversion into protocatechuate via p-cresol)(NFUNC_0007)
必須A
MMA
(NRULE_0027)
Multicomponent monooxygenase alpha subunit
MMB
(NRULE_0028)
Multicomponent monooxygenase beta subunit
FDR1
(NRULE_0032)
Oxygenase electron transfer componentSspiN1_010100028199 SspiN1_010100038044 SspiN1_010100005705 SspiN1_010100008225
MME
(NRULE_0033)
Multicomponent monooxygenase effector protein
PCHF
(NRULE_0035)
4-cresol dehydrogenase flavoprotein subunit
PCHC
(NRULE_0036)
4-cresol dehydrogenase cytochrome c subunit
PCHA
(NRULE_0037)
p-hydroxybenzaldehyde dehydrogenase
POBA
(NRULE_0038)
p-hydroxybenzoate hydroxylase
任意 
MMG1
(NRULE_0029)
Multicomponent monooxygenase gamma subunit
 
MMG2
(NRULE_0030)
Multicomponent monooxygenase gamma subunit
 
MMG3
(NRULE_0031)
Multicomponent monooxygenase gamma subunit
 
FDX1
(NRULE_0034)
Putative Rieske-type ferredoxinSspiN1_010100003433 SspiN1_010100003423 SspiN1_010100007060 SspiN1_010100007230 SspiN1_010100007240 SspiN1_010100008220 SspiN1_010100013249 SspiN1_010100024527 SspiN1_010100037354 SspiN1_010100038049
Trehalose biosynthesis (from maltose)(NFUNC_0034)
必須A
MAPA
(NRULE_0126)
Maltose phosphorylase
TREP
(NRULE_0127)
Alpha,alpha-trehalose phosphorylaseSspiN1_010100017411
B
TRES
(NRULE_0128)
Trehalose synthase
Trehalose biosynthesis (from NDP-glucose and glucose-6-phosphate)(NFUNC_0031)
必須A
TPS
(NRULE_0119)
Trehalose-phosphate synthaseSspiN1_010100021438
TPP
(NRULE_0120)
Trehalose-6-phosphate phosphataseSspiN1_010100021443 SspiN1_010100018236
Uptake of osmoprotectant(NFUNC_0061)
必須A
OPUAC
(NRULE_0213)
Osmoprotectant ABC transporter substrate-binding protein
OPUAB
(NRULE_0214)
Osmoprotectant ABC transporter permease protein
OPUAA
(NRULE_0215)
Osmoprotectant ABC transporter ATP-binding proteinSspiN1_010100026014
B
EHUB
(NRULE_0216)
Ectoine ABC transporter substrate-binding proteinSspiN1_010100000950 SspiN1_010100012144
EHUC
(NRULE_0217)
Ectoine ABC transporter permease proteinSspiN1_010100012139 SspiN1_010100000955
EHUD
(NRULE_0218)
Ectoine ABC transporter permease proteinSspiN1_010100000960 SspiN1_010100012134
EHUA
(NRULE_0219)
Ectoine ABC transporter ATP-binding proteinSspiN1_010100000965 SspiN1_010100012129
C
BCCT
(NRULE_0220)
BCCT family transporterSspiN1_010100033100 SspiN1_010100041240
D
PROP
(NRULE_0221)
Osmoprotectant transporter
E
OPUE
(NRULE_0222)
Sodium/proline symporter
F
TEAA
(NRULE_0223)
TRAP transporter substrate-binding protein TeaA
TEAB
(NRULE_0224)
TRAP transporter small transmembrane protein TeaB
TEAC
(NRULE_0225)
TRAP transporter large transmembrane protein TeaC
Vitamin B6 biosynthesis (PdxA/PdxJ pathway)(NFUNC_0060)
必須A
EPD
(NRULE_0208)
D-erythrose-4-phosphate dehydrogenase
PDXB
(NRULE_0209)
Erythronate-4-phosphate dehydrogenase
SERC
(NRULE_0210)
Phosphoserine aminotransferaseSspiN1_010100022130
PDXA
(NRULE_0211)
4-hydroxythreonine-4-phosphate dehydrogenase
PDXJ
(NRULE_0212)
Pyridoxine 5'-phosphate synthase
Vitamin B6 biosynthesis (PdxS/PdxT pathway)(NFUNC_0059)
必須A
PDXS
(NRULE_0206)
Pyridoxal biosynthesis lyase PdxSSspiN1_010100027444
PDXT
(NRULE_0207)
Glutamine amidotransferase subunit PdxTSspiN1_010100027424